anti-Anaphase Promoting Complex Subunit 15 (ANAPC15) Antikörper

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human ANAPC15 ANAPC15 25906 P60006
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Top anti-Anaphase Promoting Complex Subunit 15 Antikörper auf antikoerper-online.de

Showing 6 out of 8 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: ANAPC15 Sample Type: HT1080 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: C11orf51 Antibody [NBP1-84151] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY415516) Immunocytochemistry/Immunofluorescence: C11orf51 Antibody [NBP1-84151] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & vesicles. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   150 μL Anmelden zum Anzeigen 13 bis 16 Tage
$753.50
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Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$517.50
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   50 μL Anmelden zum Anzeigen 2 bis 3 Tage
$510.36
Details

Am meisten referenzierte anti-Anaphase Promoting Complex Subunit 15 Antikörper

  1. Human Polyclonal ANAPC15 Primary Antibody für ICC, IF - ABIN4285964 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen Anaphase Promoting Complex Subunit 15 Interaktionspartner

Human Anaphase Promoting Complex Subunit 15 (ANAPC15) Interaktionspartner

  1. cryo-EM structure of an APC (zeige APC Antikörper)/C-Cdh1 (zeige CDH1 Antikörper) complex with Apc1 (zeige SLC25A24 Antikörper)(WD40 (zeige DCAF12L2 Antikörper)) deleted showed that the mutant APC (zeige APC Antikörper)/C is locked into an inactive conformation in which the UbcH10 (zeige UBE2C Antikörper)-binding site of the catalytic module is inaccessible. Additionally, an EM density for Apc15 is not visible

  2. Anaphase promoting complex subunit 15(APC15) mediates the constant turnover of CDC20 (zeige CDC20 Antikörper) and mitotic checkpoint (zeige BUB3 Antikörper) protein complexes, allowing the spindle checkpoint assembly to respond to the attachment state of kinetochores.

  3. APC15 is required for anaphase-promoting complex/cyclosome-bound mitotic checkpoint (zeige BUB3 Antikörper) complex-dependent CDC20 (zeige CDC20 Antikörper) autoubiquitylation and degradation and for timely anaphase initiation.

Anaphase Promoting Complex Subunit 15 (ANAPC15) Antigen-Profil

Protein Überblick

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20.

Genbezeichner und Symbole assoziert mit ANAPC15

  • anaphase promoting complex subunit 15 (ANAPC15) Antikörper
  • APC15 Antikörper
  • C11orf51 Antikörper
  • C15H11orf51 Antikörper

Bezeichner auf Proteinebene für ANAPC15

anaphase-promoting complex subunit 15 , protein HSPC020 homolog

GENE ID SPEZIES
25906 Homo sapiens
505356 Bos taurus
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