anti-Amyloid beta (Abeta) Antikörper

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human Abeta Abeta 351 P05067
Anti-Ratte Abeta Abeta 54226 P08592
Anti-Maus Abeta Abeta 11820 P12023
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Top anti-beta Amyloid Antikörper auf antikoerper-online.de

Showing 10 out of 277 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of Beta Amyloid expression in HEK293T (A), Hela (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Maus Ziege Unkonjugiert ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Rind (Kuh) Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Beta Amyloid expression in mouse kidney (A), mouse heart (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Fruchtfliege Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
Details

Am meisten referenzierte anti-beta Amyloid Antikörper

  1. Human Monoclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 10 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody für ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Human beta Amyloid Primary Antibody für ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human beta Amyloid Primary Antibody für IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody für ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody für IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal beta Amyloid Primary Antibody für ELISA, WB - ABIN1573928 : Jia, Liu, Song, Pan, Chen, Cui, Wang: Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways. in The Journal of pharmacy and pharmacology 2012 (PubMed)

Weitere Antikörper gegen beta Amyloid Interaktionspartner

Human Amyloid beta (Abeta) Interaktionspartner

  1. This study applies methodologies on the initial stages of aggregation of a hexamer of Alzheimer's amyloid beta fragment 25-35 (ABETA (zeige APP Antikörper) 25-35) and finds that transitions within the hexameric aggregate are dominated by entropic barriers and speculates that especially the conformation entropy plays a major role in the formation of the fibril as a rate limiting factor.

  2. c-Abl is activated in AbetaOs exposed neurons and in Alzheimer's disease patient's brain, and the inhibition of activated c-Abl ameliorates cognitive deficits

  3. RelA (zeige NFkBP65 Antikörper), RelB (zeige RELB Antikörper) and c-Rel (zeige NFkBP65 Antikörper) can be activated by Abeta1-40, all of which mediate pro-inflammatory cytokine transcription and retinal pigment epithelium damage.

  4. specific balance between the concentrations of monomeric and fibrillar alpha-synuclein determines the outcome of the Abeta42 aggregation reaction

  5. Nuclear HSP70 (zeige HSP70 Antikörper) leads to enhancement of vaccinia H1-related phosphatase (VHR (zeige DUSP3 Antikörper)) activity via protein-protein interaction rather than its molecular chaperone (zeige HSP90AA1 Antikörper) activity, thereby suppressing excessive ERK (zeige EPHB2 Antikörper) activation. Downregulation of either VRK3 or HSP70 (zeige HSP70 Antikörper) rendered cells vulnerable to glutamate (zeige GRIN1 Antikörper)-induced apoptosis.

  6. The authors show that lipoproteins including brain (apoE (zeige APOE Antikörper)) and circulating (high-density lipoprotein, HDL (zeige HSD11B1 Antikörper)) synergize to facilitate beta-amyloid transport across bioengineered human cerebral vessels.

  7. The Network analyses identified APP (zeige APP Antikörper) expression in temporal cortex in patient with late-onset Alzheimer's disease.

  8. alpha-synuclein (Parkinson) and Abeta (zeige APP Antikörper) peptide (Alzheimer) no longer form Ca(2 (zeige CA2 Antikörper)+)-permeable pores in presence of drugs that target either cholesterol or ganglioside or both membrane lipids.

  9. APP (zeige APP Antikörper) processing is regulated throughout differentiation of cortical neurons and that amyloidogenic APP (zeige APP Antikörper) processing, as reflected by Abeta1-40/42, is associated with mature neuronal phenotypes.

  10. Authors measured cerebral morphological and neurochemical alterations using structural magnetic resonance imaging (MRI (zeige C7ORF49 Antikörper)) and proton magnetic resonance spectroscopy ((1)H-MRS) in an AD model of APP (zeige APP Antikörper)/PS1 (zeige PSEN1 Antikörper) transgenic mice.

Mouse (Murine) Amyloid beta (Abeta) Interaktionspartner

  1. Therefore, APP (zeige APP Antikörper) modulates Nav1.6 (zeige SCN8A Antikörper) sodium channels through a Go-coupled JNK (zeige MAPK8 Antikörper) pathway, which is dependent on phosphorylation of APP (zeige APP Antikörper) at Thr668.

  2. These findings suggest that in the absence of CLU (zeige CLU Antikörper), Abeta (zeige APP Antikörper) clearance shifts to perivascular drainage pathways, resulting in fewer parenchymal plaques but more CAA because of loss of CLU (zeige CLU Antikörper) chaperone activity, complicating the potential therapeutic targeting of CLU (zeige CLU Antikörper) for AD.

  3. Chronic Dyrk1 (zeige DYRK1A Antikörper) inhibition reversed cognitive deficits in Alzheimer's disease transgenic mice via reduction of APP (zeige APP Antikörper) and phosphorylated tau pathology.

  4. The results of the present study substantiate that cGMP has a role in the endocytic pathway of APP (zeige APP Antikörper) and suggest a scenario where the cyclic nucleotide enhances the production of Abeta (zeige APP Antikörper) by favoring the trafficking of APP (zeige APP Antikörper) from the cell cortex to the endolysosomal compartment.

  5. Study showed that the APP (zeige APP Antikörper) Osaka mutation has dual effects: it causes a loss-of-function of APP (zeige APP Antikörper) and gain-of-toxic-function of Abeta (zeige APP Antikörper), though the latter seems to come out only after the former causes GABAergic depletion. Also present OSK-KI mice as a mouse model to replicate the hereditary form of recessive familial Alzheimer's disease.

  6. Results show that the duration of UP state, which is a key feature of cortical synaptic integration occurring predominantly during slow-wave sleep, is significantly increased in the prefrontal cortex in the absence of APP (zeige APP Antikörper). This was accompanied by a specific reduction in the glutamine synthetase (zeige GLUL Antikörper) and tissue GABA content and sequential upregulation in the levels of GABA-B receptor expression.

  7. results support the hypothesis that the miR (zeige MLXIP Antikörper)-132/212 network, including Sirt1 (zeige SIRT1 Antikörper) and likely other target genes, contributes to abnormal Abeta (zeige APP Antikörper) metabolism and senile plaque deposition in AD.

  8. Activation of CaMKIV (zeige CAMK4 Antikörper) by soluble amyloid-beta1-42 impedes trafficking of axonal vesicles and impairs activity-dependent synaptogenesis

  9. Abpp (zeige APP Antikörper) /KPI(R13I) mutant mice were similarly deficient as Abpp (zeige APP Antikörper) knock out mice in regulating cerebral thrombosis in experimental models of carotid artery thrombosis and intracerebral hemorrhage.

  10. The cognitive function of APP (zeige APP Antikörper)/PS1 (zeige PSEN1 Antikörper) mice was impaired at 10months of age; moreover, the hypermetabolic state identified in various brain regions at 5months of age was also significantly decreased.

beta Amyloid (Abeta) Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Amyloid beta (Abeta) Antikörper

  • amyloid beta precursor protein (APP) Antikörper
  • amyloid beta precursor protein (app) Antikörper
  • amyloid beta precursor protein (App) Antikörper
  • amyloid beta (A4) precursor protein (App) Antikörper
  • aaa Antikörper
  • Abeta Antikörper
  • Abpp Antikörper
  • ad1 Antikörper
  • Adap Antikörper
  • Ag Antikörper
  • appi Antikörper
  • betaApp Antikörper
  • ctfgamma Antikörper
  • Cvap Antikörper
  • E030013M08Rik Antikörper
  • PN-II Antikörper
  • pn2 Antikörper

Bezeichner auf Proteinebene für anti-Amyloid beta (Abeta) Antikörper

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPEZIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
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