anti-Amyloid beta (Abeta) Antikörper

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Zusätzlich bieten wir Ihnen beta Amyloid Proteine (3) und beta Amyloid Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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Top anti-beta Amyloid Antikörper auf

Showing 10 out of 178 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg 5 bis 7 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of Beta Amyloid expression in HEK293T (A), Hela (B) whole cell lysates. 200 μL 13 bis 14 Tage
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL 13 bis 14 Tage
Human Maus Unkonjugiert ELISA, IF, WB Fluorescent microscopy image (appotome) of 6 months-old APP/PS1 mouse hypocampus and somatosensory cortex. Double staining: in blue, nuclei DAPI staining. In red, Amyloid plaques. Immunofluorescence slices with the anti-amyloid beta antibody from different mouse genotypes. Wild type (WT), APP/PS1 and APP KO. In red, amyloid plaques. 100 μg 6 bis 7 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of Beta Amyloid expression in mouse kidney (A), mouse heart (B) whole cell lysates. 200 μL 13 bis 14 Tage
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 0.1 mg 6 bis 8 Tage
Human Maus Unkonjugiert IHC, ELISA Abeta oligomer-specific antibody was adsorbed to Nunc-Immuno MaxiSorp plates (Nunc, Roskilde, Denmark) at 2 ug/ml in PBS. 1 ml of a 10 uM Aβ(1-42) sample containing a small fraction of Aβ-oligomers was separated using a superdex G75 (10/30) column. Aβ-fractions collected from the SEC were allowed to bind to OMAB plates for 20 minutes at 0°C. All fractions were analyzed and bound Aβ was detected using a polyclonal rabbit anti-Aβ antibody (ABIN249343) at a 1:1000 dilution followed by an anti-rabbit HRP-conjugated secondary antibody at a 1:5000 dilution (GE healthcare). ECBlue (Medicago, Uppsala, Sweden) was used as a substrate for HRP and the signal was detected by measuring the absorbance at 450 nm. Blocking solution and antibody-dilutions were made with 5% Non-fat dry milk in PBST and all washes were performed with PBS containing 0.1% Tween-20 (PBST). 10 µm of coronal sections from fresh-frozen transgenic mouse brain mutant (A) and wild type (B). Post-fixation in 4% formaldehyde solution, 5 min. OMAB antibody diluted 1:500, incubation at 4ºC ON. Mouse on mouse HRP-Polymer kit according to company instructions. Biocare Medical: BC-MM510 (Histolab) DAB substrate kit for peroxidase. Vector Laboratories: SK-4100 (ImmunKemi) Counterstained with Mayers HTX. 50 μg 6 bis 8 Tage
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Verfügbar
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using Amyloid-beta Polyclonal Antibody. 100 μL Verfügbar
Human Maus Unkonjugiert IHC 100 μg 2 bis 3 Tage

Am meisten referenzierte anti-beta Amyloid Antikörper

  1. Human Monoclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 20 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody für ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody für ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  5. Human beta Amyloid Primary Antibody für ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal beta Amyloid Primary Antibody für ELISA (Capture), IF - ABIN190335 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody für ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody für IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal beta Amyloid Primary Antibody für ELISA, WB - ABIN1573928 : Jia, Liu, Song, Pan, Chen, Cui, Wang: Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways. in The Journal of pharmacy and pharmacology 2012 (PubMed)

Weitere Antikörper gegen beta Amyloid Interaktionspartner

Human Amyloid beta (Abeta) Interaktionspartner

  1. We found that individuals with elevated beta-amyloid aggregation had a blunted cerebrovascular response compared to non-elevated individuals

  2. in cholinergic neurons from Drosophila, beta-amyloid (Abeta) peptides Abeta40 and Abeta42 both induce an increase in spontaneous activity.

  3. These data indicate that the sAbeta1-42 may play a dual role during inflammatory process, wherein, it may be involved in protecting the cells from inflammatory damage due to TNF-alpha.

  4. We observed that over-expression of PIEZO1 in HEK293 cells increased cell migration velocity ~10-fold, and both enantiomeric A-beta peptides and GsMTx4 independently inhibited migration, demonstrating involvement of PIEZO1 in cell motility.

  5. We found amyloid measures to be sensitive early on in predicting subsequent early tau deposition

  6. APP facilitate an early step in thrombus formation when amyloid beta (Abeta) peptides accumulate in cerebral vessel walls or atherosclerotic plaques.

  7. The differing patterns in cerebral amyloid angiopathy within individuals may relate to the relative tissue burdens of the two major forms of Abeta, with higher levels of Abeta40 promoting a more 'aggressive' form of CAA, and higher levels of Abeta42(3) favouring a greater plaque burden

  8. we provide a novel method to convert standardized uptake value ratios-levels into PET-Abeta phase estimates that can be easily translated into neuropathological phases of Abeta-deposition

  9. Influence of the familial Alzheimer's disease-associated T43I mutation on the transmembrane structure and gamma-secretase processing of the C99 peptide

  10. results may explain the role of hAChE-S in Abeta deposition and aggregation, as amyloidogenic hAChE-S beta-sheet species might seed Abeta aggregation.

  11. Prior work has shown that beta-amyloid and Apolipoprotein E epsilon4 combine to influence memory decline in nondemented older adults. This study indicate that increasing age may further exacerbate these effects.

  12. these results suggest an important role of the allosteric sodium binding site for GPR3 activity and open a possible avenue for the modulation of Abeta production in the Alzheimer's Disease.

  13. results uncover a mechanism by which PP2A Aalpha regulates Abeta protein stability and activity

  14. Solid-state NMR reveals a comprehensive view of the dynamics of the flexible, disordered N-terminal domain of amyloid-beta fibrils.

  15. This study showed that 24-month-old AppNL/NL mice, despite presenting an age dependent increase in insoluble amyloid-beta oligomers in the prefrontal cortex, they do not develop amyloid plaque deposition, reactive gliosis, or cognitive deficits.

  16. This study demonstrated that Progress of Brain Amyloid Deposition in Familial Alzheimer's Disease with Taiwan D678H APP Mutation.

  17. these data reveal an important role for APP in the amyloidogenic aspects of AD but challenge the idea that increased APP levels are solely responsible for increasing specific phosphorylated forms of tau or enhanced neuronal cell death in Down syndrome-associated AD pathogenesis.

  18. This study explores the mechanism of ABETA (1-40) fiber elongation. A Markov state model shows that the unfolded monomer is trapped at the end of the fiber in a set of interconverting antiparallel beta hairpin conformations.

  19. A novel lysosome-to-mitochondria signaling pathway disrupted by amyloid-beta oligomers.

  20. These findings suggest a role for TREM2 in the brain of HIV+ individuals may deserve more investigation as a biomarker for HIV-associated neurocognitive disorders and as a possible therapeutic

Mouse (Murine) Amyloid beta (Abeta) Interaktionspartner

  1. The findings demonstrate that chronic noise exposure exacerbated Alzheimer's disease-like neuropathology, possibly by disrupting Wnt signaling and triggering aberrant tau hyperphosphorylation and amyloid beta peptides in the prefrontal cortex and hippocampus.

  2. A novel lysosome-to-mitochondria signaling pathway disrupted by amyloid-beta oligomers.

  3. Together these data indicate that ONA induces APP expression and that gamma-secretase cleavage of APP releases AICD, which upregulates JNK3 leading to RGC death. This pathway may be a novel target for neuronal protection in optic neuropathies and other forms of neurotrauma.

  4. In addition to regulating aspects of neuronal metabolism, APP is an important regulator of whole body energy expenditure and glucose homeostasis under high fat feeding conditions.

  5. These findings indicate that under physiological conditions, expression of APP in cerebral vascular endothelium plays an important protective function by maintaining constitutive expression of eNOS .

  6. NRBF2 plays an important role in regulating degradation of APP-C-terminal fragments through modulating autophagy.

  7. These results provide evidence that both central circadian rhythms and local clock function influence Abeta dynamics and plaque formation.

  8. These data identified APP and APLP2 as modulators of normal myelination and demyelination/remyelination conditions.

  9. these findings suggest that endogenous Abeta is involved in memory forgetting in the normal brain.

  10. pterostilbene attenuated the neuroinflammatory response induced by Abeta1-42 in microglia through inhibiting the NLRP3/caspase-1 inflammasome pathway, indicating that pterostilbene might be an effective therapy for AD.

  11. Abeta40 and Abeta42 demonstrated distinct distribution kinetics in plasma and brain compartments, and insulin differentially modulated their distribution.

  12. APP/GBR complex formation links presynaptic GBR trafficking to Abeta formation.

  13. APP knockout increases synaptic GluA1, PSD-95 and synaptophysin expression and reduces drebrin expression.

  14. data indicate that Drp1 is a direct target of Cdk5, and Cdk5-mediated phosphorylation of Drp1 at Serine 579 regulates Abeta1-42 induced mitochondrial fission and neuronal toxicity.

  15. miR98 reduced the production of Abeta and improved oxidative stress and mitochondrial dysfunction through activation of the Notch signaling pathway by binding to HEY2 in Alzheimer's disease mice.

  16. Heme and Hb suppress immune activity of primary mouse astrocytes by reducing expression of several proinflammatory cytokines (e.g. RANTES (regulated on activation normal T cell expressed and secreted)) and the scavenger receptor CD36 and reducing internalization of Abeta(1-42) by astrocytes.

  17. extracellular cholesterol concentration in serum under conditions of Npc1 deficiency can influence intracellular cholesterol content/distribution and lysosomal efficacy, triggering the accumulation of toxic APP-cleaved products, eventually leading to cell death.

  18. Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.

  19. This study provides a novel mechanism underlying aggregation of Abeta peptides via BC1 induction of APP mRNA translation.

  20. This study uncovered two clear phases in the life of APP23 mice: developmental and aging. Development displays similarities to young carriers of familial Alzheimer's disease (AD) mutations. All gene expression differences between APP23 and control mice correlate with aging. Age-related expression changes appear exacerbated/accelerated in APP23 mice.

beta Amyloid (Abeta) Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Amyloid beta (Abeta) Antikörper

  • amyloid beta precursor protein (APP) Antikörper
  • amyloid beta precursor protein (app) Antikörper
  • amyloid beta precursor protein (App) Antikörper
  • amyloid beta (A4) precursor protein (App) Antikörper
  • aaa Antikörper
  • Abeta Antikörper
  • Abpp Antikörper
  • ad1 Antikörper
  • Adap Antikörper
  • Ag Antikörper
  • appi Antikörper
  • betaApp Antikörper
  • ctfgamma Antikörper
  • Cvap Antikörper
  • E030013M08Rik Antikörper
  • PN-II Antikörper
  • pn2 Antikörper

Bezeichner auf Proteinebene für anti-Amyloid beta (Abeta) Antikörper

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
Ausgewählte Anbieter für anti-beta Amyloid (Abeta) Antikörper
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