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NPEPPS encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. Zusätzlich bieten wir Ihnen Aminopeptidase Puromycin Sensitive Kits (9) und Aminopeptidase Puromycin Sensitive Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal NPEPPS Primary Antibody für ELISA, WB - ABIN408680
Karsten, Sang, Gehman, Chatterjee, Liu, Lawless, Sengupta, Berry, Pomakian, Oh, Schulz, Hui, Wiedau-Pazos, Vinters, Binder, Geschwind, Jackson: A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. in Neuron 2006
findings show that by promoting autophagic protein clearance, PSA helps protect against accumulation of aggregation-prone proteins and proteotoxicity
the purification and characterization of a puromycin-sensitive aminopeptidase from zebrafish
cytosolic peptidases(puromycin-sensitive aminopeptidase (PSA), aminopeptidase B (APB (zeige RNPEP Antikörper)) and pyroglutamyl-peptidase I (zeige PGPEP1 Antikörper) (PGI (zeige BGN Antikörper)) ) may be involved in colorectal carcinogenesis
Studies indicate the critical role of M1 aminopeptidases ERAP1 (zeige ERAP1 Antikörper), ERAP2 (zeige ERAP2 Antikörper) and NPEPPS in immune-mediated diseases.
MiR-614 inhibited cell invasion and proliferationa targeting PSA in lung cancer cells, PGCL3
Elevation of NPEPPS activity blocks accumulation of hyperphosphorylated TAU protein and slows down the progression of Alzheimer's disease.
ApPS (zeige CTSB Antikörper) Y394F exhibited a 3.3-fold lower affinity for RB-3014, a transition state inhibitor, indicating that Tyr394 is involved in transition state stabilization
PSA (zeige PLAG1 Antikörper) gene was downregulated in PC-3 (zeige PCSK1 Antikörper) cells that were treated with CoCl(2). PSA (zeige PLAG1 Antikörper) is involved in the proliferation, migration, and invasion of PC-3 (zeige PCSK1 Antikörper) cells, which are important determinants of metastasis, via a mechanism that involves MMP-9 (zeige MMP9 Antikörper) modulation.
Nucleocytoplasmic transfer of cyclin dependent kinase 5 (zeige CDK5 Antikörper) and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum
These data indicate that PSA may play a role in limiting MHC class I Ag presentation in dendritic cells in vivo but that it is not essential for generating most MHC class I-presented peptides or for stimulating CTL responses to several Ags (zeige GLA Antikörper).
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.
, lethal (3) 06226
, puromycin sensitive aminopeptidase
, puromycin-sensitive aminopeptidase
, aminopeptidase puromycin sensitive
, puromycin-sensitive aminopeptidase-like
, cytosol alanyl aminopeptidase
, metalloproteinase MP100