Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide Proteine (ADH1A)

ADH1A encodes a member of the alcohol dehydrogenase family. Zusätzlich bieten wir Ihnen ADH1A Antikörper (35) und ADH1A Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ADH1A 11522 P00329
Ratte ADH1A ADH1A 24172 P06757
ADH1A 124 P07327
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Top ADH1A Proteine auf

Showing 7 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
Wheat germ Human GST tag   10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Uromastyx hardwickii His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

ADH1A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , ,
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Am meisten referenzierte ADH1A Proteine

  1. Human ADH1A Protein expressed in Wheat germ - ABIN1305977 : Mutka, Green, Verderber, Richards, Looker, Chlipala, Rosenthal: ADH IB expression, but not ADH III, is decreased in human lung cancer. in PLoS ONE 2013 (PubMed)
    Show all 2 Pubmed References

Weitere Proteine zu Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) Interaktionspartnern

Mouse (Murine) Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) Interaktionspartner

  1. Overexpression of an ADH1 transgene protected against tunicamycin-induced cardiac dysfunction through attenuation of ER stress, oxidative stress, and PTEN-Akt (zeige AKT1 Proteine)-mTOR (zeige FRAP1 Proteine) regulated autophagy.

  2. Data indicate a potential change in aldehyde dehydrogenase (ALDH) activity of proliferating beta cells during pregnancy.

  3. This study demonistrated that adh1 knockout mice as possible rodent models for presymptomatic Parkinson's disease.

  4. Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

  5. Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase (zeige AKR1A1 Proteine)

  6. ADH1 functions as the primary enzyme responsible for efficient oxidative clearance of excess retinol, thus providing protection and increased survival during vitamin A toxicity

  7. Crbp1 (zeige RBP1 Proteine)-/- mice also exhibited increased metabolism of a dose of retinol into retinoic acid, and this increased metabolism was not observed in Crbp1 (zeige RBP1 Proteine)-/-/Adh1-/- mice

  8. Cellular expression of Adh1 in the GI tract was studied.

  9. After chronic ethanol consumption, the activity of the MEOS increases, with an associated rise in cytochrome P450, especially CYP2E1 (zeige CYP2E1 Proteine), most conclusively shown in alcohol dehydrogenase (zeige AKR1A1 Proteine) negative deer mice.

  10. Liver disease in the alcoholic is due not only to malnutrition but also to ethanol's hepatotoxicity linked to its metabolism by means of the alcohol dehydrogenase (zeige AKR1A1 Proteine) and CYP2E1 (zeige CYP2E1 Proteine) pathways and the resulting production of toxic acetaldehyde.

Human Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A) Interaktionspartner

  1. High ADH (zeige AVP Proteine) expression is associated with Prostate Cancer.

  2. Results suggest a potential role of alcohol dehydrogenase (ADH) class I as a marker for renal cell carcinoma (zeige MOK Proteine) (RCC (zeige XRCC1 Proteine)).

  3. Data indicate that the up-regulation of aldehyde dehydrogenase-1 (ALDH1) after neoadjuvant chemotherapy (NAC) predicts poor survival in locally advanced breast cancer.

  4. Unde-rexpression of the ADH1 gene, which influences the transformation of the extracellular matrix, plays a probable role in the etiology of uterine fibroid.

  5. high levels of ADH1 transcription are implicated in fluconazole resistance in C. albicans and that the mRNA expression levels of ADH1 are positively correlated with those of CDR1, CDR2 and FLU1.

  6. common ADH (zeige AVP Proteine) variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  7. High ADH1 is associated with endometrial cancer.

  8. ADH1A variation predisposes to personality traits and substance dependence

  9. GATA-2 (zeige GATA2 Proteine) and HNF-3beta (zeige FOXA2 Proteine) regulate the human alcohol dehydrogenase 1A (ADH1A) gene.

  10. The oxidative pathway of ethanol metabolism via ADH and ALDH does not play a role in pancreatic carcinogenesis.

ADH1A Protein Überblick

Protein Überblick

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Genbezeichner und Symbole assoziert mit ADH1A

  • alcohol dehydrogenase 1 (adh1)
  • alcohol dehydrogenase 1A (LOC744064)
  • alcohol dehydrogenase ADH1 (ADH1)
  • Alcohol dehydrogenase 1 (Dvir\Adh1)
  • alcohol dehydrogenase 1 (class I) (Adh1)
  • alcohol dehydrogenase 1A (class I), alpha polypeptide (ADH1A)
  • ADC1 Protein
  • Adh Protein
  • Adh-1 Protein
  • Adh-1-t Protein
  • Adh-1e Protein
  • Adh-1t Protein
  • Adh-3e Protein
  • ADH-AA Protein
  • ADH1 Protein
  • Adh1-e Protein
  • Adh1-t Protein
  • Adh1a Protein
  • Adh1c Protein
  • Adh1tl Protein
  • Adh3-e Protein
  • AI194826 Protein
  • Dvir\\Adh Protein
  • Dvir\\GJ18208 Protein
  • dvir_GLEANR_2771 Protein
  • GJ18208 Protein

Bezeichner auf Proteinebene für ADH1A

class I alcohol dehydrogenase, alpha subunit , Adh1-PA , Dvir\\Adh1-PA , Dvir\\GJ18208-PA , GJ18208-PA , alcohol dehydrogenase , alcohol dehydrogenase 1 , ADH-A2 , alcohol dehydrogenase 1 temporal, liver , alcohol dehydrogenase 1, complex , alcohol dehydrogenase 1, electrophoretic , alcohol dehydrogenase 3, electrophoretic , alcohol dehydrogenase A subunit , class I alcohol dehydrogenase , alcohol dehydrogenase (class I), alpha polypeptide , alcohol dehydrogenase 1C (class I), gamma polypeptide , ADH, alpha subunit , alcohol dehydrogenase 1 (class I), alpha polypeptide , alcohol dehydrogenase 1A , alcohol dehydrogenase subunit alpha , aldehyde reductase , alcohol dehydrogenase 1 (subunit A) , alchohol dehydrogenase 1A

496861 Xenopus (Silurana) tropicalis
744064 Pan troglodytes
854068 Saccharomyces cerevisiae S288c
6634390 Drosophila virilis
11522 Mus musculus
24172 Rattus norvegicus
124 Homo sapiens
280982 Bos taurus
100009283 Oryctolagus cuniculus
707682 Macaca mulatta
100172370 Pongo abelii
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