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alpha subunit of class I alcohol dehydrogenase\; metabolizes a wide variety of substrates including ethanol, hydroxysteroids and lipid peroxidation products [RGD, Feb 2006]..
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Overexpression of an ADH1 (zeige ADH1A Antikörper) transgene protected against tunicamycin-induced cardiac dysfunction through attenuation of ER stress, oxidative stress, and PTEN-Akt (zeige AKT1 Antikörper)-mTOR (zeige FRAP1 Antikörper) regulated autophagy.
Data indicate a potential change in aldehyde dehydrogenase (ALDH) activity of proliferating beta cells during pregnancy.
This study demonistrated that adh1 (zeige ADH1A Antikörper) knockout mice as possible rodent models for presymptomatic Parkinson's disease.
Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice
Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase (zeige AKR1A1 Antikörper)
ADH1 (zeige ADH1A Antikörper) functions as the primary enzyme responsible for efficient oxidative clearance of excess retinol, thus providing protection and increased survival during vitamin A toxicity
Crbp1 (zeige RBP1 Antikörper)-/- mice also exhibited increased metabolism of a dose of retinol into retinoic acid, and this increased metabolism was not observed in Crbp1 (zeige RBP1 Antikörper)-/-/Adh1 (zeige ADH1A Antikörper)-/- mice
Cellular expression of Adh1 (zeige ADH1A Antikörper) in the GI tract was studied.
After chronic ethanol consumption, the activity of the MEOS increases, with an associated rise in cytochrome P450 (zeige CYP Antikörper), especially CYP2E1 (zeige CYP2E1 Antikörper), most conclusively shown in alcohol dehydrogenase (zeige AKR1A1 Antikörper) negative deer mice.
Liver disease in the alcoholic is due not only to malnutrition but also to ethanol's hepatotoxicity linked to its metabolism by means of the alcohol dehydrogenase (zeige AKR1A1 Antikörper) and CYP2E1 (zeige CYP2E1 Antikörper) pathways and the resulting production of toxic acetaldehyde.
alpha subunit of class I alcohol dehydrogenase\; metabolizes a wide variety of substrates including ethanol, hydroxysteroids and lipid peroxidation products
, alcohol dehydrogenase 1
, alcohol dehydrogenase 1 temporal, liver
, alcohol dehydrogenase 1, complex
, alcohol dehydrogenase 1, electrophoretic
, alcohol dehydrogenase 3, electrophoretic
, alcohol dehydrogenase A subunit
, class I alcohol dehydrogenase
, alcohol dehydrogenase (class I), alpha polypeptide
, alcohol dehydrogenase 1C (class I), gamma polypeptide
, alcohol dehydrogenase 1B (class I), beta polypeptide
, beta polypeptide