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The protein encoded by AKR7A2 belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. Zusätzlich bieten wir Ihnen AKR7A2 Antikörper (80) und AKR7A2 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
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AKR7A2 physically interacts with CYGB.
induced expression in human monocytes following exposure to Aflatoxin B1
AKR7A2 contributes to protection against MG-induced toxicity.
structure and tissue-related expression of AFAR genes on chromosome 1
The human aldo-keto reductase AKR7A2 has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to gamma-Hydroxybutyrate in human brain
The human AFAR gene family maps to a genomic region in 1p36 of frequent hemizygous deletions in various human cancers.
Aflatoxin B(1) aldehyde reductase (AKR7A2) was confirmed to be only highly expressed in pancreatic cancer, not in normal adjacent pancreas and benign tumors.
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.
AFB1 aldehyde reductase 1
, AFB1-AR 1
, SSA reductase
, aflatoxin B1 aldehyde reductase member 2
, aflatoxin beta1 aldehyde reductase
, aldoketoreductase 7
, succinic semialdehyde reductase
, aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
, aldo-keto reductase family 7, member A2 L homeolog