Adenosine Monophosphate Deaminase 1 Proteine (AMPD1)

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Zusätzlich bieten wir Ihnen Adenosine Monophosphate Deaminase 1 Antikörper (92) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
AMPD1 270 P23109
AMPD1 229665  
AMPD1 25028 P10759
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
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Wheat germ Human GST tag 10 μg 11 bis 12 Tage
$340.00
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
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Hefe Ratte His tag   1 mg 60 bis 71 Tage
$4,185.50
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AMPD1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Adenosine Monophosphate Deaminase 1 (AMPD1) Interaktionspartnern

Rabbit Adenosine Monophosphate Deaminase 1 (AMPD1) Interaktionspartner

  1. Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase.

Human Adenosine Monophosphate Deaminase 1 (AMPD1) Interaktionspartner

  1. T allele of AMPD1 gene C34T polymorphism may be correlated with LVEF, LVEDD and SBP, which plays a protective role in the cardiac functions and blood pressure in cardiovascular disease patients.

  2. The metabolic-chronotropic response is decreased in skeletal muscle MAD deficiency, suggesting a biological mechanism by which AMPD1 gene exerts cardiac effect

  3. Variations in AMPD1, CPT2, and PGYM genes are not associated with the onset, susceptibility, or severity of chronic fatigue syndrome.

  4. Common polymorphism of the AMPD1 gene (C34T) is strongly associated with essential hypertension.

  5. AMPD1 could have a profound influence on cholinergic neurotransmission and sleep; further studies are mandatory

  6. AMPD1 34C>T variant is associated with higher infection susceptibility to community acquired pneumonia but not to ventilator associated pneumonia in sepsis pateints

  7. Mutational variants in AMPD1 contribute to autism risk in Han Chinese population, via mitochondria dysfunction and cell necrosis.

  8. The best response to creatine in terms of physical performance was presented by AMPD1 CC genotype.

  9. The present study demonstrated a positive effect of C34T AMPD1 gene polymorphism in aortic stiffness and in inflammatory status in a high risk population of CAD subjects.

  10. Our other studies on the metabolic impact of AMPD1 C34T mutation revealed decrease in AMPD activity.

  11. Alpinists show significantly higher frequencies of T allele compared to controls.

  12. AMPD1 gene polymorphism C34T can be considered as a marker of liability to the high-speed and strength muscular activity.

  13. In a study of a Spanish and 2 North African cohorts, frequency of the AMPD1 C34T mutation was lower in Berbers compared with the Alpujarra cohort. The GDF8 K153R substitution showed little variability among the three cohorts.

  14. There was a lower frequency of the AMPD1 exon 2 T34 allele in elite Polish power-oriented athletes. The data suggested that the C allele may help athletes to attain elite status in power-oriented sports.

  15. The researchers found evidence that the T allele polymorphism of the AMPD1 gene is associated with negative factor in athletic performance

  16. AMPD1 gene mutations are associated with obesity and diabetes in Polish patients with cardiovascular diseases.

  17. some physico-chemical properties of AMP-deaminase isolated from cardiac muscle of a 10-year-old boy heterozygote for this mutation

  18. A G468T AMPD1 mutant allele contributes to the high incidence of myoadenylate deaminase deficiency in the Caucasian population.

  19. Significantly higher frequency of mutation among donors with healthy hearts used for transplantation. Lower frequency in dysfunctional donor hearts. Frequency of C34T mutation in chronic heart failure was not different. (Review)

  20. The AMPD1 C34T polymorphism influences transplant-free cardiovascular survival in the setting of ischemic left ventricular dysfunction.

Pig (Porcine) Adenosine Monophosphate Deaminase 1 (AMPD1) Interaktionspartner

  1. Two novel single nucleotide polymorphisms in the AMPD1 promoter region are associated with carcass traits.

  2. molecular cloning: the distribution of genotypes among Min pig, Yorkshire and Duroc are extremely significantly different

  3. The deduced amino acid sequence of AMPD1 contains an AMP deaminase signature sequence (SLSTDDP). RT-PCR analyses showed that AMPD1 was expressed specifically in skeletal muscle.

Cow (Bovine) Adenosine Monophosphate Deaminase 1 (AMPD1) Interaktionspartner

  1. Our results indicate that the deletion mutation in the AMPD1 gene is associated with production traits, and may be used for marker-assisted selection in beef cattle breeding programs.

  2. These results suggest that the 18-bp deletion mutation in AMPD1 may influence the carcass traits in Qinchuan cattle.

Mouse (Murine) Adenosine Monophosphate Deaminase 1 (AMPD1) Interaktionspartner

  1. AMPD1 is an adenosine monophosphate deaminase that catalyzes the deamination of AMP to IMP. An elevated AMP level and almost complete lack of IMP was detected in the skeletal muscle of E18.5 Ampd1(tm1a/tm1a) mice.

  2. AMPD1 deficiency activates AMPK/Akt/mTORC1/p70 S6 kinase axis in skeletal muscle after high fat diet challenge, but not in normal chow diet. These changes may contribute to improve insulin resistance.

  3. Disruption of the AMPD1 gene leads to a less severe state of insulin resistance, improved glucose tolerance and enhanced insulin clearance in mice fed a high-fat diet. Data suggest that AMPD may be a new drug target for reversing insulin resistance.

  4. AMPD1 deficiency is acquired prior to overt muscle inflammation and is responsible, at least in part, for the muscle weakness that occurs in the mouse model of myositis.

Adenosine Monophosphate Deaminase 1 (AMPD1) Protein Überblick

Protein Überblick

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Genbezeichner und Symbole assoziert mit AMPD1

  • adenosine monophosphate deaminase 1 (AMPD1)
  • N-acetyl-anhydromuranmyl-L-alanine amidase (ampD1)
  • N-acetylmuramoyl-L-alanine amidase (ampD1)
  • Negative regulator of beta-lactamase expression (ampD1)
  • adenosine monophosphate deaminase 1 (ampd1)
  • adenosine monophosphate deaminase 1 (Ampd1)
  • adenosine monophosphate deaminase 1 (isoform M) (ampd1)
  • AI553520 Protein
  • Ampd-1 Protein
  • Ampd01 Protein
  • ampd1 Protein
  • MAD Protein
  • MADA Protein
  • RATAMPD01 Protein
  • zgc:77905 Protein

Bezeichner auf Proteinebene für AMPD1

N-acetyl-anhydromuranmyl-L-alanine amidase , N-acetylmuramoyl-L-alanine amidase , Negative regulator of beta-lactamase expression , adenosine monophosphate deaminase 1 , AMP deaminase 1-like , adenosine monophosphate deaminase 1 (isoform M) , AMP deaminase 1 , AMPD , adenosine monophosphate deaminase-1 (muscle) , myoadenylate deaminase , skeletal muscle AMPD , Ampd

GENE ID SPEZIES
100065374 Equus caballus
2766844 Yersinia pestis biovar Microtus str. 91001
4607045 Azoarcus sp. BH72
7815531 Rickettsia africae ESF-5
100196648 Salmo salar
100414418 Callithrix jacchus
100445019 Pongo abelii
100344490 Oryctolagus cuniculus
100540618 Meleagris gallopavo
100552392 Anolis carolinensis
100590300 Nomascus leucogenys
270 Homo sapiens
606901 Canis lupus familiaris
100101472 Sus scrofa
512748 Bos taurus
229665 Mus musculus
25028 Rattus norvegicus
457144 Pan troglodytes
772125 Gallus gallus
393867 Danio rerio
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