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ACOT13 encodes a member of the thioesterase superfamily. Zusätzlich bieten wir Ihnen Acyl-CoA Thioesterase 13 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.
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THEM2 protein from zebrafish (fTHEM2) was expressed in Escherichia coli and purified by Ni-affinity and gel-filtration chromatography. fTHEM2 crystals were obtained using the sitting-drop vapour-diffusion method with PEG 10 (zeige PEG10 Antikörper) 000 as precipitant.
Markers in DYX2 (zeige KIAA0319 Antikörper) genes KIAA0319 (zeige KIAA0319 Antikörper) and FAM65B (zeige FAM65B Antikörper) were associated with cortical thickness in the left developing orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 (zeige KIAA0319 Antikörper) and ACOT13 were suggestively associated with overall fractional anisotropy and left pars (zeige EPRS Antikörper) opercularis cortical thickness, respectively.
study failed to show any association of THEM2 SNPs with developmental dyslexia in an Indian population.
The results of this study confirmed that both FOXP2 (zeige FOXP2 Antikörper) and KIAA0319 (zeige KIAA0319 Antikörper)/TTRAP (zeige TDP2 Antikörper)/THEM2 genes play an important role in human language development, but probably through different cerebral pathways.
analysis of human thioesterase superfamily member 2 crystal structure
Yeast two-hybrid screening using libraries prepared from mouse liver and embryo identified Them2 (thioesterase superfamily member 2) and the homeodomain transcription factor Pax3 (paired box gene 3 (zeige PAX3 Antikörper)), respectively, as PC-TP (zeige PCTP Antikörper)-interacting proteins.
The physiological role of hTHEM2 involves catalysis of the hydrolysis of cytosolic medium-to-long-chain acyl-CoA (zeige GNPAT Antikörper) thioesters.
These findings reveal a primary role for Them2 in promoting mitochondrial oxidation of fatty acids and glucose in the liver.
PC-TP (zeige PCTP Antikörper)-THEM2 complex reduces phosphorylation and stability of IRS2 (zeige IRS2 Antikörper) and increases stability of the TSC1 (zeige TSC1 Antikörper)-TSC2 (zeige TSC2 Antikörper) complex
Them2 functions in brown adipose tissue to suppress adaptive increases in energy expenditure.
This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.
acyl-CoA thioesterase 13
, acyl-coenzyme A thioesterase 13
, thioesterase superfamily member 2
, hypothalamus protein HT012