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Controls several aspects of neuronal morphogenesis\; essential for optic lobe development, EcR-B1 expression in larval brains, mushroom body remodeling, dorsal neuron morphogenesis and motoneuron axon guidance.
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Human Monoclonal Actbeta Primary Antibody für IHC (p), ELISA - ABIN2477269
Adebajo, Eastmond: Hepatotoxicity to several nonsteroidal anti-inflammatory drugs with diclofenac induced histological changes. in Clinical rheumatology 1992
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The authors find that both arms of the TFGb signaling pathways specifically instruct the pale photoreceptor subset in R8. The Activin arm utilizes the three ligands dActb, Daw, and Myo non-redundantly to activate Babo and downstream dSmad2 in R8, while the BMP arm signals by way of Dpp and Gbb to Tkv and Mad.
a conserved role for activin in enhancing adipokinetic hormone/glucagon signaling and glycemic control, is reported.
Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction
These data reveal how insulin signaling can regulate aging through control of Activin signaling that in turn controls autophagy, representing a potentially conserved molecular basis for longevity assurance
These results suggest that the Activin signaling pathway is required for producing the proper number of neurons to enable normal connection of incoming photoreceptor axons to their targets.
Controls several aspects of neuronal morphogenesis\; essential for optic lobe development, EcR-B1 expression in larval brains, mushroom body remodeling, dorsal neuron morphogenesis and motoneuron axon guidance. Ligands Actbeta and daw act redundantly through the Activin receptor Babo and its transcriptional mediator Smad2 (Smox), to regulate neuroblast numbers and proliferation rates in the developing larval brain.
, activin 102F
, activin beta