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The protein encoded by ACRBP is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. Zusätzlich bieten wir Ihnen Acrosin Binding Protein Kits (10) und Acrosin Binding Protein Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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ACRBP can be used as a molecular marker for spermatogenesis and sexual maturity in horses.
Down regulation of OY-TES-1 increased expression of apoptosis-regulated protein caspase-3 (zeige CASP3 Antikörper), and decreased expression of cell cycle-regulated protein cyclin E (zeige CCNE1 Antikörper), migration/invasion-regulated proteins MMP2 (zeige MMP2 Antikörper) and MMP9 (zeige MMP9 Antikörper).
OY-TES-1 downregulation in liver cancer cells caused 2 opposite effects on cell proliferation: promotion by upregulating CCND2 (zeige CCND2 Antikörper) and CDCA3 (zeige CDCA3 Antikörper), and inhibition by CD9 (zeige CD9 Antikörper) upregulation and NANOG (zeige NANOG Antikörper) downregulation. OY-TES-1 may play multiple roles in liver cancer.
OY-TES-1 was expressed in ovarian cancer (OC) tissues with a high proportion, and some of OC tissues presented OY-TES-1 expression in high level vs OC adjacent tissues.
OY-TES-1 is frequently expressed in colorectal carcinoma and is able to induce humoral immune response spontaneously in CRC (zeige CALR Antikörper) patients.
The down-regulation of OY-TES-1 expression in bone marrow-derived mesenchymal stem cells caused cell growth inhibition, cell cycle arrest, apoptosis induction and migration ability attenuation.
High ACRBP expression correlated with reduced survival time and faster relapse among ovarian cancer patients.
We showed identification of HLA-A24 (zeige CD164 Antikörper)-binding OY-TES-1 peptide, TES (zeige TES Antikörper)(401-409) (KTPFVSPLL) recognized by CD8 (zeige CD8A Antikörper) T-cells.
Data show that sperm protein 32 (sp32) expression was higher and significantly higher in capacitated and post-acrosomal reaction sperms than in frozen-thawed sperms and fresh semen, respectively.
ACRBP-null male mice showed a severely reduced fertility, because of malformation of the acrosome.
Two forms of Acrbp mRNA-wild-type Acrbp-W and variant Acrbp-V5 mRNAs-were generated by alternative splicing of Acrbp in the mouse.
Data suggest that the fertility defect in PCSK4 (proprotein convertase subtilisin/kexin type 4 (zeige PCSK4 Antikörper)) knockout mice is due, in part, to altered processing/proteolysis of ACRBP as well as structural abnormalities in sperm heads and acrosomes.
The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon.
acrosin binding protein
, proacrosin binding protein sp32
, acrosin-binding protein-like
, acrosin-binding protein
, cancer/testis antigen 23
, cancer/testis antigen OY-TES-1
, proacrosin binding protein
, proacrosin-binding protein sp32
, Acrosin-binding protein
, proacrosin-binding protein (sp32)