anti-Acetyl-CoA Acetyltransferase 2 (ACAT2) Antikörper

The product of ACAT2 is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. Zusätzlich bieten wir Ihnen ACAT2 Kits (30) und ACAT2 Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ACAT2 39 Q9BWD1
ACAT2 110460 Q8CAY6
ACAT2 308100 Q5XI22
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Top anti-ACAT2 Antikörper auf antikoerper-online.de

Showing 10 out of 106 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Maus Unkonjugiert FACS, IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ACAT2 Antibody Titration: </b>1.0ug/ml<br><b>Positive Control: </b>K562 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ACAT2 Antibody Titration: </b>2.0ug/ml<br><b>Positive Control: </b>K562 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Hund Maus Unkonjugiert FACS, IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: ACAT2 Antibody [NBP1-89525] - Staining of human testis shows strong cytoplasmic positivity in leydig cells. Immunocytochemistry/ Immunofluorescence: ACAT2 Antibody [NBP1-89525] - Staining of human cell line A-431 shows positivity in cytoplasm & mitochondria. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Maus Unkonjugiert FACS, IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Maus Unkonjugiert FACS, IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Maus Unkonjugiert FACS, IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: ACAT2 Antibody [NBP1-89526] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: ACAT2 Antibody [NBP1-89526] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in leydig cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human HepG2 Cells; Lane2: Porcine Liver Tissue; Lane3: Mouse Liver Tissue. Figure. Western Blot; Sample: Recombinant ACAT2, Human. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details

ACAT2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)


Rat (Rattus)
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Am meisten referenzierte anti-ACAT2 Antikörper

  1. Human Polyclonal ACAT2 Primary Antibody für IHC, IHC (p) - ABIN4277554 : Go, Srivastava, Hernandez-Ono, Gang, Smith, Booth, Ginsberg, Mani: The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. in Cell metabolism 2014 (PubMed)

  2. Human Polyclonal ACAT2 Primary Antibody für ICC, IF - ABIN4277555 : Martinez-Outschoorn, Lin, Whitaker-Menezes, Howell, Sotgia, Lisanti: Ketone body utilization drives tumor growth and metastasis. in Cell cycle (Georgetown, Tex.) 2012 (PubMed)

Weitere Antikörper gegen ACAT2 Interaktionspartner

Human Acetyl-CoA Acetyltransferase 2 (ACAT2) Interaktionspartner

  1. Lipid-induced stabilization of ACAT2 ameliorates lipotoxicity from excessive cholesterol and fatty acid. Cysteine ubiquitylation of ACAT2 constitutes an important mechanism for sensing lipid-overload-induced ROS and fine-tuning lip (zeige ROS1 Antikörper)id homeostasis.

  2. data demonstrate that the ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters (CE/SE), and suggest that the excretion of lipoproteins containing the ACAT2-catalyzed CS/SE may avoid cytotoxicity

  3. results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion

  4. Low ACAT2 expression is associated with clear cell renal cell carcinoma (zeige MOK Antikörper).

  5. results show that the enzymatic activity of mutant Glu(14)Gly is approximately two times higher than wildtype, and that this increase is primarily due to the increased expression and/or stability of the mutant ACAT2 protein

  6. TG-interacting factor 1 (Tgif1 (zeige TGIF1 Antikörper)) is an important repressor of SOAT2 (zeige SOAT2 Antikörper) gene expression.

  7. Results show that DLAT (zeige DLAT Antikörper) and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD (zeige PGD Antikörper) protein.

  8. CDX2 (zeige CDX2 Antikörper), a known positive regulator of hepatocyte differentiation, was regulated by miR (zeige MLXIP Antikörper)-181d and directly activated SOAT2 (zeige SOAT2 Antikörper) gene expression.

  9. Reduced ACAT2 is associated with impaired butyrate oxidation in ulcerative colitis.

  10. HNF4alpha positively regulates ACAT2 gene expression at mRNA level. Overexpression of HNF4alpha increased ACAT2 expression, whereas knockdown of HNF4alpha decreased ACAT2 expression.

Mouse (Murine) Acetyl-CoA Acetyltransferase 2 (ACAT2) Interaktionspartner

  1. lipid-induced stabilization of ACAT2 (zeige SOAT2 Antikörper) ameliorates lipotoxicity from excessive cholesterol and fatty acid. This unconventional cysteine ubiquitylation of ACAT2 (zeige SOAT2 Antikörper) constitutes an important mechanism for sensing lipid-overload-induced ROS (zeige ROS1 Antikörper) and fine-tuning lipid homeostasis.

  2. These studies demonstrate that SOAT2 is a negative regulator of LXR-stimulated fecal neutral sterol loss in mice.

  3. Hepatic knockdown of SOAT2 (zeige SOAT2 Antikörper) in apoB100 (zeige APOB Antikörper)-only, LDLr (zeige LDLR Antikörper)(-/-) mice resulted in remodeling of aortic atherosclerotic lesions into a stable phenotype, suggesting SOAT2 (zeige SOAT2 Antikörper) is a viable target for the treatment of atherosclerosis.

  4. Intestine-specific MTP (zeige LAPTM4A Antikörper) and global ACAT2 (zeige SOAT2 Antikörper) deficiency lowers acute cholesterol absorption with chylomicrons and HDLs (zeige CSF1R Antikörper)

  5. SOAT2 (zeige SOAT2 Antikörper) causes hepatic cholesterol to be swiftly mobilized and packaged onto nascent lipoproteins that feed cholesterol into the TICE pathway for fecal excretion.

  6. effect the loss of SOAT2 (zeige SOAT2 Antikörper) function has on tissue esterified cholesterol sequestration in lysosomal acid lipase (zeige LIPA Antikörper)-deficient mice in a model of cholesteryl ester storage disease

  7. ACAT2 (zeige SOAT2 Antikörper) seems to be a hepatic player affecting the cholesterol fluxes fated to VLDL or to HDL (zeige HSD11B1 Antikörper), the latter via up-regulation of ABCA1 (zeige ABCA1 Antikörper)

  8. Aortic atherosclerosis development was significantly lower in SOAT2 (zeige SOAT2 Antikörper) knock-out mice.

  9. ACAT2 increases cholesterol absorption efficiency by providing cholesterol esters for chylomicron transport, but 1 copy of the Acat2 gene, providing approximately 50% of ACAT2 mRNA and enzyme activity, was as effective as 2 copies in promoting cholesterol absorption.

  10. handling of sterols by the intestine involves both G5G8 and ACAT2 but that an additional factor (possibly Niemann-Pick C1-like 1) may be key in determining absorption efficiency

Arabidopsis thaliana Acetyl-CoA Acetyltransferase 2 (ACAT2) Interaktionspartner

  1. The AACT2-derived acetoacetyl CoA pool generates isoprenoids that are required for normal growth and development. AACT2 is essential and cannot be replaced by AACT1. AACT1 and AACT2 exhibit differential spatial and temporal expression patterns.

Pig (Porcine) Acetyl-CoA Acetyltransferase 2 (ACAT2) Interaktionspartner

  1. ACAT2 might contribute more to metabolic processes than ACAA2 (zeige ACAA2 Antikörper) in swine.

ACAT2 Antigen-Profil

Protein Überblick

This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Genbezeichner und Symbole assoziert mit ACAT2

  • acetyl-CoA acetyltransferase 2 (ACAT2) Antikörper
  • sterol O-acyltransferase 2 (SOAT2) Antikörper
  • acetyl-Coenzyme A acyltransferase 2 (CNA05060) Antikörper
  • acetyl-CoA acetyltransferase 2 (acat2) Antikörper
  • acetyl-Coenzyme A acetyltransferase 2 (Acat2) Antikörper
  • sterol O-acyltransferase 2 (Soat2) Antikörper
  • acetyl-CoA acetyltransferase 2 (Acat2) Antikörper
  • acetyl-CoA acetyltransferase 2 S homeolog (acat2.S) Antikörper
  • acetoacetyl-CoA thiolase 2 (ACAT2) Antikörper
  • Ab2-076 Antikörper
  • ACACT2 Antikörper
  • ACAT2 Antikörper
  • Acat3 Antikörper
  • acetoacetyl-CoA thiolase 2 Antikörper
  • ARGP2 Antikörper
  • AW742799 Antikörper
  • D15Wsu97e Antikörper
  • EMB1276 Antikörper
  • EMBRYO DEFECTIVE 1276 Antikörper
  • fb10a06 Antikörper
  • fb53f08 Antikörper
  • MIF21.12 Antikörper
  • MIF21_12 Antikörper
  • Tcp-1x Antikörper
  • Tcp1-rs1 Antikörper
  • wu:fb10a06 Antikörper
  • wu:fb53f08 Antikörper

Bezeichner auf Proteinebene für ACAT2

acetoacetyl Coenzyme A thiolase , acetyl-CoA acetyltransferase, cytosolic , acetyl-CoA transferase-like protein , cytosolic acetoacetyl-CoA thiolase , ACAT-2 , acyl Co-A: cholesterol acyltransferase 2 , acyl coenzyme A:cholesterol acyltransferase 2 , acyl-CoA:cholesterol acyltransferase 2 , acyl-coenzyme A:cholesterol acyltransferase 2 , cholesterol acyltransferase 2 , acetyl-Coenzyme A acyltransferase 2 , etID39354.20 , t-complex protein 1, related sequence 1 , acyl-CoA:cholesterol acyltransferase , acetyl-Coenzyme A acetyltransferase 2 , acetyl-Coenzyme A acetyltransferase 3 , acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) , acetyl-CoA acetyltransferase 2 , acetyl-CoA acetyltransferase, cytosolic-like

GENE ID SPEZIES
39 Homo sapiens
8435 Homo sapiens
3253349 Cryptococcus neoformans var. neoformans JEC21
30643 Danio rerio
110460 Mus musculus
223920 Mus musculus
308100 Rattus norvegicus
394562 Xenopus (Silurana) tropicalis
398120 Xenopus laevis
421587 Gallus gallus
484063 Canis lupus familiaris
497249 Monodelphis domestica
512044 Bos taurus
834876 Arabidopsis thaliana
100172365 Pongo abelii
100410799 Callithrix jacchus
100477493 Ailuropoda melanoleuca
100152303 Sus scrofa
100340500 Oryctolagus cuniculus
100714379 Cavia porcellus
101111975 Ovis aries musimon
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