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The membrane-associated protein encoded by ABCA6 is a member of the superfamily of ATP-binding cassette (ABC) transporters.
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Human Polyclonal ABCA6 Primary Antibody für ELISA - ABIN449692
Kaminski, Wenzel, Piehler, Langmann, Schmitz: ABCA6, a novel a subclass ABC transporter. in Biochemical and biophysical research communications 2001
A rare missense variant in ABCA6 (rs77542162, p.Cys1359Arg, frequency 0.034), found in a Dutch population, is predicted to be deleterious with respect to blood cholesterol levels.
Results suggest a possible role for multidrug resistance genes ABCA10 (zeige ABCA10 Antikörper) and ABCA6 in follicular lymphoma survival and add to the evidence that genetic variation in CD46 (zeige CD46 Antikörper) and IL8 (zeige IL8 Antikörper) may have prognostic implications follicular lymphoma.
These data provide evidence for an essential role of FoxO (zeige FOXO3 Antikörper) proteins in the transcription of ABCA6 in human vascular endothelial cells.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.
ATP-binding cassette sub-family A member 6
, ATP-binding cassette, sub-family A (ABC1), member 6
, ATP-binding cassette, sub-family A, member 6
, ATP-binding cassette sub-family A member 6-like
, ABC transporter ABCA6
, ATP-binding cassette A6
, ATP-binding cassette transporter sub-family A member 6