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The protein encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. Zusätzlich bieten wir Ihnen ARFGAP3 Antikörper (79) und ARFGAP3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
ADP-ribosylation factor GTPase activating protein 1
, ADP-ribosylation factor GTPase-activating protein 3
, ARF GAP 3
, ADP-ribosylation factor GTPase activating protein 3
, ADP ribosylation factor GTPase activating protein 3 S homeolog