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arfgap2 encodes a zinc-finger-containing GTPase-activating protein for ADP ribosylation factor 1 (ARF1), a small GTPase that plays a role in coatomer-mediated vesicular trafficking. Zusätzlich bieten wir Ihnen arfgap2 Kits (12) und arfgap2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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This gene encodes a zinc-finger-containing GTPase-activating protein for ADP ribosylation factor 1 (ARF1), a small GTPase that plays a role in coatomer-mediated vesicular trafficking. This gene product stimulates the hydrolysis of ARF1-bound GTP, which may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. It may regulate the retrograde transport from the Golgi complex to the endoplasmic reticulum. Expression of this gene has been shown to be controlled by inhibitor of DNA binding 1 (Id1). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 6.
ADP-ribosylation factor GTPase activating protein 2
, zinc finger protein 289, ID1 regulated
, ADP-ribosylation factor GTPase-activating protein 2
, ARF GAP 2
, GTPase-activating protein ZNF289
, zinc finger protein 289
, ADP-ribosylation factor GTPase-activating protein 2-like