(ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
custom-made
ABCG8
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
ABCG8
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
ABCG8
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
ABCG8
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
ATP binding cassette subfamily G member 8 (ABCG8) Proteine ATP-binding cassette sub-family G member 8 (PTRG_02054) Proteine ABC transporter G family protein (abcG8) Proteine ATP-binding cassette, sub-family G (WHITE), member 8 (abcg8) Proteine ATP binding cassette subfamily G member 8 (Abcg8) Proteine 1300003C16Rik Proteine AI114946 Proteine DDBDRAFT_0167690 Proteine DDBDRAFT_0191232 Proteine DDB_0167690 Proteine DDB_0191232 Proteine GBD4 Proteine sterolin-2 Proteine STSL Proteine zgc:172358 Proteine