anti-Transglutaminase 2 (TGM2) Antikörper

Bezeichnung:
anti-Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Antikörper (TGM2)
Auf www.antikoerper-online.de finden Sie aktuell 301 Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Transglutaminase 2 Kits (40) und Transglutaminase 2 Proteine (29) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 385 Transglutaminase 2 Produkte verfügbar.
Synonyme:
fc12b04, G-ALPHA-h, GNAH, G[a]h, TG2, TGase2, TgaseII, TGC, TGL2, TGM2, tTG, tTGas, wu:fc12b04, zgc:101081, zgc:136700

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anti-Human Transglutaminase 2 Antikörper:

anti-Rat (Rattus) Transglutaminase 2 Antikörper:

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Am meisten referenzierte anti-Transglutaminase 2 Antikörper

  1. Human Polyclonal Transglutaminase 2 Primary Antibody für IHC (p), IP - ABIN181299 : Greenberg, Birckbichler, Rice: Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992 (PubMed)
    Zeige alle 2 Referenzen für 181299

  2. Human Polyclonal Transglutaminase 2 Primary Antibody für ELISA, WB - ABIN253171 : Verma, Wang, Manavathi, Fok, Mann, Kumar, Mehta: Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. in Cancer research 2006 (PubMed)

  3. Human Polyclonal Transglutaminase 2 Primary Antibody für ICC, IF - ABIN4362059 : Faria, Henriques, Matos, Daha, Pestana, Seelen: Combined C4d and CD3 immunostaining predicts immunoglobulin (Ig)A nephropathy progression. in Clinical and experimental immunology 2015 (PubMed)

  4. Human Polyclonal Transglutaminase 2 Primary Antibody für EIA, WB - ABIN360168 : Parsons, Yosipovitch, Sheehan, Sangüeza, Greenberg, Sane: Transglutaminases: the missing link in nephrogenic systemic fibrosis. in The American Journal of dermatopathology 2007 (PubMed)

  5. Cow (Bovine) Polyclonal Transglutaminase 2 Primary Antibody für IHC, WB - ABIN2782978 : Verma, Guha, Wang, Fok, Koul, Abbruzzese, Mehta: Tissue transglutaminase regulates focal adhesion kinase/AKT activation by modulating PTEN expression in pancreatic cancer cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

  6. Cow (Bovine) Polyclonal Transglutaminase 2 Primary Antibody für WB - ABIN2782979 : Li, Bagchi, Bagchi: Identification of a signaling pathway involving progesterone receptor, calcitonin, and tissue tranglutaminase in Ishikawa endometrial cells. in Endocrinology 2006 (PubMed)

  7. Dog (Canine) Monoclonal Transglutaminase 2 Primary Antibody für Func, IF - ABIN180313 : Birckbichler, Upchurch, Patterson, Conway: A monoclonal antibody to cellular transglutaminase. in Hybridoma 1985 (PubMed)

Weitere Antikörper gegen Transglutaminase 2 Interaktionspartner

Human Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Interaktionspartner

  1. High transglutaminase 2 expression is associated with colorectal cancer.

  2. GTP binding (zeige RND2 Antikörper), but not transamidase activity, is required for TG2-dependent cancer stem cell invasion, migration and tumour formation. However, transamidase site-specific inhibitors reduce cancer stem cell survival.

  3. these findings ascribe a novel function for ALDH1A3 (zeige ALDH1A3 Antikörper) in an aggressive glioma stem cells phenotype via the up-regulation of tissue transglutaminase

  4. Data show that carboxyl-terminus of Hsp70-interacting protein (CHIP) promotes polyubiquitination of transglutaminase 2 (TG2) and its subsequent proteasomal degradation.

  5. No clear evidence for an association of tTGA or EMA (zeige ETFA Antikörper) seropositivity with incident coronary heart disease outcomes, suggesting that tTG autoimmunity is unlikely to be the biological link between coeliac disease and CHD (zeige CHDH Antikörper).

  6. the TG2 enzymatic activity was negligibly affected by bexarotene treatment. It is important to control TG2 overexpression since its upregulation is correlated with tumor transformation and drug resistance. Bexarotene also showed in vivo tumoricidal effects in a GBM xenograft mouse model. Therefore, we suggest bexarotene as a more beneficial differentiation agent than ATRA for GBM.

  7. Thus it can be concluded that human transglutaminases differ in harboring damaging variants and TGM2 is under purifying selection suggesting that it may have so far not revealed physiological functions.

  8. mechanical load-induced TGM2 expression and enzyme activity is involved in the progression of the calcification of ligamentum flavum.

  9. interconnected network of TG2/NF-kappaB (zeige NFKB1 Antikörper) and IL6 (zeige IL6 Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling with autophagy regulation in MCL (zeige FH Antikörper) cells.

  10. TGM2 expression was not significantly correlated with ovarian cancer antineoplastic drug resistance.

Cow (Bovine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Interaktionspartner

  1. TG2 contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (zeige AKT1 Antikörper) signaling, likely via its serotonylation.

  2. An important role for TG2, mediated by intracellular calcium fluxes and HIF1A (zeige HIF1A Antikörper), in hypoxia-induced pulmonary artery smooth muscle cells proliferation.

  3. externalized GTP (zeige AK3 Antikörper)-bound TG2 serves as a molecular switch for differentiation of chondrocytes to a hypertrophic, calcifying phenotype in a manner that does not require either TG2 transamidation activity or fibronectin (zeige FN1 Antikörper) binding

Mouse (Murine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Interaktionspartner

  1. data suggest that the anti-angiogenic mechanism of the celiac disease-specific autoantibodies involves extracellular TG2 and inhibited endothelial cell mobility

  2. Kidney fibrosis in aging may represent a natural outcome of upregulated endostatin (zeige COL18A1 Antikörper) (EST (zeige MAP3K8 Antikörper)) and transglutaminase 2 (TG2), but more likely it appears to be a result of cumulative stresses occurring on the background of synergistically acting geronic (aging) proteins, EST (zeige MAP3K8 Antikörper) and TG2.

  3. findings support the potential pathophysiological relevance of TRX (zeige TXN Antikörper) in celiac disease and establish the Cys (zeige DNAJC5 Antikörper)(370)-Cys (zeige DNAJC5 Antikörper)(371) disulfide bond of TG2 as one of clearest examples of an allosteric disulfide bond in mammals.

  4. TG2 controls the formation of VEGF165-heparan sulfate proteoglycan complexes

  5. TG2 is a novel inhibitor of adipogenesis.

  6. LPS (zeige TLR4 Antikörper)-induced TG2 was involved in the mechanism of pinocytosis and phagocytosis in microglia.

  7. Inhibition of tissue transglutaminase resulted in a reduced rate of compaction compared to controls during early remodeling (up to 2 days). In contrast, inhibition of lysyl oxidase (zeige LOX Antikörper) did not alter the early compaction.

  8. TG2-deficient mice exhibited hyper inflammatory responses after being challenged with monosodium urate crystals.

  9. Data presented in this study show that TG2 plays a key role in cellular dynamics and consequently influences the energetic metabolism.

  10. TG2 functions as a critical signal for allergic lung responses.

Transglutaminase 2 (TGM2) Antigen-Profil

Beschreibung des Gens

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Transglutaminase 2 (TGM2)

  • transglutaminase 2 (TGM2) Antikörper
  • transglutaminase 2, C polypeptide A (tgm2a) Antikörper
  • transglutaminase 2, C polypeptide (Tgm2) Antikörper
  • transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2) Antikörper
  • transglutaminase 2b (tgm2b) Antikörper
  • transglutaminase 2 (LOC100352148) Antikörper
  • fc12b04 Antikörper
  • G-ALPHA-h Antikörper
  • GNAH Antikörper
  • G[a]h Antikörper
  • TG2 Antikörper
  • TGase2 Antikörper
  • TgaseII Antikörper
  • TGC Antikörper
  • TGL2 Antikörper
  • TGM2 Antikörper
  • tTG Antikörper
  • tTGas Antikörper
  • wu:fc12b04 Antikörper
  • zgc:101081 Antikörper
  • zgc:136700 Antikörper

Bezeichner auf Proteinebene für TGM2

C polypeptide, protein-glutamine-gamma-glutamyltransferase , TG(C) , TGase C , TGase H , TGase-2 , TGase-H , protein-glutamine gamma-glutamyltransferase 2 , protein-glutamine-gamma-glutamyltransferase , tissue transglutaminase , transglutaminase C , transglutaminase H , transglutaminase-2 , TG2c , transglutaminase 2 , tissue-type transglutaminase , transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) , TGC , C polypeptide , TG C

GENE ID SPEZIES
7052 Homo sapiens
447909 Danio rerio
56083 Rattus norvegicus
469937 Pan troglodytes
281528 Bos taurus
323856 Danio rerio
396432 Gallus gallus
100127492 Sus scrofa
485867 Canis lupus familiaris
100352148 Oryctolagus cuniculus
21817 Mus musculus
100379228 Cavia porcellus
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