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anti-PTK2B (PTK2B) Antikörper

Bezeichnung:
anti-PTK2B Protein tyrosine Kinase 2 beta Antikörper (PTK2B)
Auf www.antikoerper-online.de finden Sie aktuell 243 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PTK2B Kits (20) und PTK2B Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 292 PTK2B Produkte verfügbar.
Synonyme:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk

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Am meisten referenzierte anti-PTK2B Antikörper

  1. Human Polyclonal PTK2B Primary Antibody für IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. in The Journal of clinical investigation 2004 (PubMed)
    Zeige alle 5 Referenzen für ABIN196952

  2. Human Monoclonal PTK2B Primary Antibody für IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. in Experimental hematology 2004 (PubMed)
    Zeige alle 3 Referenzen für ABIN1724705

  3. Human Polyclonal PTK2B Primary Antibody für IHC, ELISA - ABIN1532112 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. in Nature 1995 (PubMed)
    Zeige alle 2 Referenzen für ABIN1532112

  4. Human Polyclonal PTK2B Primary Antibody für ELISA, WB - ABIN1533144 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. in Genomics 1997 (PubMed)
    Zeige alle 2 Referenzen für ABIN1533144

  5. Human Polyclonal PTK2B Primary Antibody für IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Zeige alle 2 Referenzen für ABIN197440

  6. Human Polyclonal PTK2B Primary Antibody für IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. in Bone 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PTK2B Primary Antibody für WB - ABIN2779800 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. in American journal of physiology. Cell physiology 2004 (PubMed)

Weitere Antikörper gegen PTK2B Interaktionspartner

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. A cell-culture study using an inhibitor of estrogen receptors and an in vivo experiment with ovariectomized mice suggested that the estrogenic activity of 8-PN contributed to recovery from disuse muscle atrophy through activation of an Akt (zeige AKT1 Antikörper) phosphorylation pathway. These data strongly suggest that 8-PN is a naturally occurring compound that could be used as a nutritional supplement to aid recovery from disuse muscle atroph

  2. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt (zeige AKT1 Antikörper) indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  3. Data show that Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) and MAPK (zeige MAPK1 Antikörper) pathways were activated in ovine pulmonary adenocarcinoma (OPA) lung and envelope (Env (zeige ERVW-1 Antikörper)) of Jaagsiekte sheep retrovirus (JSRV) transfected NIH 3T3 cells.

  4. Results suggest that SC79 compound activates Akt (zeige AKT1 Antikörper)-Nrf2 (zeige NFE2L2 Antikörper) signaling to protect osteoblasts from dexamethasone (Dex).

  5. In conclusion, we have identified that ARL15 acts as an insulin (zeige INS Antikörper)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1 (zeige IRS1 Antikörper)/PDPK1 (zeige PDPK1 Antikörper)/AKT (zeige AKT1 Antikörper) insulin (zeige INS Antikörper) pathway by interacting with its GAP ASAP2 (zeige ASAP2 Antikörper) and activating PDPK1 (zeige PDPK1 Antikörper). This research may provide new insights into GTPase (zeige RACGAP1 Antikörper)-mediated insulin (zeige INS Antikörper) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (zeige INS Antikörper) sensitizati

  6. Taken together, our findings imply that KLF15 possesses potential anti-hypertrophic and anti-fibrotic functions, possibly via regulation of cell death pathways and the inhibition of Akt/mTOR axis. KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases.

  7. Menin (zeige MEN1 Antikörper) binds on the promoter of Inhbb (zeige INHBB Antikörper) gene where it favours the recruitment of Ezh2 (zeige EZH2 Antikörper) via an indirect mechanism involving Akt (zeige AKT1 Antikörper)-phosphorylation.

  8. A role of AKT (zeige AKT1 Antikörper) in the regulatory T cell differentiation process. TGF-beta (zeige TGFB1 Antikörper) induces the phosphorylation of Akt (zeige AKT1 Antikörper) in CD4 (zeige CD4 Antikörper)+ T cells.

  9. 4-PBA reverses autophagic dysfunction and improves insulin (zeige INS Antikörper) sensitivity in adipose tissue of obese mice via Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling partly, which could be regarded as novel opportunities for treatment of insulin (zeige INS Antikörper) resistance.

  10. These studies reveal a novel mechanism in which CYP2J2 (zeige CYP2J2 Antikörper) and epoxyeicosatrienoic acids enhanced Akt1 (zeige AKT1 Antikörper) nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (zeige PIK3CA Antikörper)-Akt/PKB (zeige AKT1 Antikörper) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  2. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  3. Studies suggest that PYK2 is a common downstream effector of ErbB (zeige EGFR Antikörper) and IL8 (zeige IL8 Antikörper) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  4. Pyk2 is a key downstream signaling molecules of CCR7 (zeige CCR7 Antikörper) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  5. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  6. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (zeige LPXN Antikörper).

  7. Src (zeige SRC Antikörper) has a role in priming Pyk2 (but not FAK (zeige PTK2 Antikörper)) phosphorylation and subsequent activation downstream of integrins

  8. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  9. FAK (zeige PTK2 Antikörper) and PYK2 functioned redundantly to promote the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway by phosphorylating GSK3beta (zeige GSK3b Antikörper)(Y216) to reinforce pathway output-beta-catenin (zeige CTNNB1 Antikörper) accumulation and intestinal tumorigenesis.

  10. This study identified Pyk2 as a cellular component required for the intracellular trafficking of HPV16 during infection.

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B Antigen-Profil

Beschreibung des Gens

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Antikörper
  • thymoma viral proto-oncogene 1 (Akt1) Antikörper
  • protein tyrosine kinase 2 beta (PTK2B) Antikörper
  • protein tyrosine kinase 2 beta (Ptk2b) Antikörper
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) Antikörper
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) Antikörper
  • Akt Antikörper
  • CADTK Antikörper
  • CAKB Antikörper
  • CAKbeta Antikörper
  • E430023O05Rik Antikörper
  • FADK2 Antikörper
  • FAK2 Antikörper
  • PKB Antikörper
  • PKB/Akt Antikörper
  • PKBalpha Antikörper
  • PTK Antikörper
  • Pyk2 Antikörper
  • Rac Antikörper
  • Raftk Antikörper

Bezeichner auf Proteinebene für PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPEZIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-PTK2B (PTK2B) Antikörper
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