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anti-PTK2B (PTK2B) Antikörper

Bezeichnung:
anti-PTK2B Protein tyrosine Kinase 2 beta Antikörper (PTK2B)
Auf www.antikoerper-online.de finden Sie aktuell 242 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PTK2B Kits (19) und PTK2B Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 289 PTK2B Produkte verfügbar.
Synonyme:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk

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Am meisten referenzierte anti-PTK2B Antikörper

  1. Human Polyclonal PTK2B Primary Antibody für IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. in The Journal of clinical investigation 2004 (PubMed)
    Zeige alle 5 Referenzen für ABIN196952

  2. Human Monoclonal PTK2B Primary Antibody für IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. in Experimental hematology 2004 (PubMed)
    Zeige alle 3 Referenzen für ABIN1724705

  3. Human Polyclonal PTK2B Primary Antibody für IHC, ELISA - ABIN1532112 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. in Nature 1995 (PubMed)
    Zeige alle 2 Referenzen für ABIN1532112

  4. Human Polyclonal PTK2B Primary Antibody für IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Zeige alle 2 Referenzen für ABIN197440

  5. Human Polyclonal PTK2B Primary Antibody für ELISA, WB - ABIN1533144 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. in Genomics 1997 (PubMed)
    Zeige alle 2 Referenzen für ABIN1533144

  6. Human Polyclonal PTK2B Primary Antibody für IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. in Bone 2015 (PubMed)

  7. Chicken Polyclonal PTK2B Primary Antibody für WB - ABIN2779801 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. in American journal of physiology. Cell physiology 2004 (PubMed)

Weitere Antikörper gegen PTK2B Interaktionspartner

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (zeige AKT1 Antikörper)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (zeige AKT1 Antikörper) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.

  2. At fertilization, Pyk2 and p-Pyk2 were detected predominantly in sperm heads and the oocyte cytoplasm. Upon formation of male and female pronuclei, Pyk2 and its activated form accumulate in the two pronuclei. Pyk2 was in blastomere nuclei and the pre-blastula cytoplasm. Pyk2 and its activated form then localized to the perinuclear regions, where blastula cells come into contact with each other.

  3. the activation of ERK5 (zeige MAPK7 Antikörper)-AKT (zeige AKT1 Antikörper)-FoxO3a (zeige FOXO3 Antikörper) signaling pathways by fluid shear stress resulted in a decreased expression of FasL (zeige FASL Antikörper) and Bim (zeige BCL2L11 Antikörper) and an inhibition of caspase-3 (zeige CASP3 Antikörper) activation, which exerts a protective effect that prevents osteoblasts from apoptosis.

  4. Only when suboptimal doses of Akt (zeige AKT1 Antikörper)-Pdpk1 (zeige PDPK1 Antikörper) interaction inhibitor NSC156529 were used an additive effect with Notch (zeige NOTCH1 Antikörper) inhibition was seen. We conclude that the Akt (zeige AKT1 Antikörper) pathway inhibitor NSC156529 is potentially useful as single treatment for liver tumors with hyperactivated Akt (zeige AKT1 Antikörper) signaling.

  5. BAY 1125976 is a potent and highly selective allosteric AKT1 (zeige AKT1 Antikörper)/2 inhibitor.

  6. These findings indicated that VPA's neuroprotective effect in the MPP(+)-model of Parkinson's disease is associated with GSK3beta (zeige GSK3b Antikörper) phosphorylation via Akt (zeige AKT1 Antikörper) and ERK (zeige EPHB2 Antikörper) activation in the mitochondrial intrinsic apoptotic pathway.

  7. PLIO treatment inhibited nuclear factorkappaB (NFkappaB) nuclear translocation in B16F10 cells. In addition, PLIO treatment inhibited the phosphorylation of c-Jun (zeige JUN Antikörper) Nterminal kinases and AKT (zeige AKT1 Antikörper)

  8. this study shows that Irbesartan can ameliorate hyperlipidemia and liver steatosis by upregulating Akt (zeige AKT1 Antikörper) signaling pathway and inducing liver autophagy

  9. BDNF (zeige BDNF Antikörper)-overexpression may not only facilitate the recovery of locomotor function via AKT (zeige AKT1 Antikörper) pathway, but also contributed simultaneously to thermal hyperalgesia after spinal cord injury

  10. Data suggest that expression, processing, and activation of (that is, signal transduction via) Notch1 (neurogenic locus notch homolog protein 1 (zeige NOTCH1 Antikörper)), Pten (phosphatase and tensin homolog (zeige PTEN Antikörper)), and Akt1 (thymoma viral proto-oncogene 1) are involved in oogenesis; oogenesis proceeds via both recruitment of primordial follicles and proliferation of granulosa cells.

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. Studies suggest that PYK2 is a common downstream effector of ErbB (zeige EGFR Antikörper) and IL8 (zeige IL8 Antikörper) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  2. Pyk2 is a key downstream signaling molecules of CCR7 (zeige CCR7 Antikörper) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  3. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  4. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (zeige LPXN Antikörper).

  5. Src (zeige SRC Antikörper) has a role in priming Pyk2 (but not FAK (zeige PTK2 Antikörper)) phosphorylation and subsequent activation downstream of integrins

  6. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  7. FAK (zeige PTK2 Antikörper) and PYK2 functioned redundantly to promote the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway by phosphorylating GSK3beta (zeige GSK3b Antikörper)(Y216) to reinforce pathway output-beta-catenin (zeige CTNNB1 Antikörper) accumulation and intestinal tumorigenesis.

  8. This study identified Pyk2 as a cellular component required for the intracellular trafficking of HPV16 during infection.

  9. These results suggest that melatonin exerts anti-migratory and anti-invasive effects on glioma cells in response to hypoxia via reactive oxygen species-alphavbeta3 integrin-FAK (zeige PTK2 Antikörper)/Pyk2 signaling pathways.

  10. data suggest a novel role for FAK (zeige PTK2 Antikörper) in GPVI (zeige GP6 Antikörper)-dependent ROS (zeige ROS1 Antikörper) formation and platelet activation and elucidate a proximal signaling role for FAK (zeige PTK2 Antikörper) within the GPVI (zeige GP6 Antikörper) pathway.

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Interaktionspartner

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B Antigen-Profil

Beschreibung des Gens

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) Antikörper
  • thymoma viral proto-oncogene 1 (Akt1) Antikörper
  • protein tyrosine kinase 2 beta (PTK2B) Antikörper
  • protein tyrosine kinase 2 beta (Ptk2b) Antikörper
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) Antikörper
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) Antikörper
  • Akt Antikörper
  • CADTK Antikörper
  • CAKB Antikörper
  • CAKbeta Antikörper
  • E430023O05Rik Antikörper
  • FADK2 Antikörper
  • FAK2 Antikörper
  • PKB Antikörper
  • PKB/Akt Antikörper
  • PKBalpha Antikörper
  • PTK Antikörper
  • Pyk2 Antikörper
  • Rac Antikörper
  • Raftk Antikörper

Bezeichner auf Proteinebene für PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPEZIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-PTK2B (PTK2B) Antikörper
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