CSK Proteine (CSK)

C-Src tyrosine Kinase Proteine (CSK)
Auf www.antikoerper-online.de finden Sie aktuell 25 C-Src tyrosine Kinase (CSK) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CSK Antikörper (201) und CSK Kits (16) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 258 CSK Produkte verfügbar.
alle Proteine anzeigen Gen GeneID UniProt
CSK 1445 P41240
CSK 12988 P41241
CSK 315707 P32577

Weitere Synonyme anzeigen

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Am meisten referenzierte CSK Proteine

  1. Mouse (Murine) CSK Protein expressed in Baculovirus infected Insect Cells - ABIN2008380 : Bräuninger, Holtrich, Strebhardt, Rübsamen-Waigmann: Isolation and characterization of a human gene that encodes a new subclass of protein tyrosine kinases. in Gene 1992 (PubMed)

  2. Human CSK Protein expressed in Wheat germ - ABIN1350517 : Jo, Park, Lee, Ahn, Kim, Park, Choi: SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes. in PLoS ONE 2014 (PubMed)

Weitere Proteine zu CSK Interaktionspartnern

Human C-Src tyrosine Kinase (CSK) Interaktionspartner

  1. H2O2-induced Csk translocation to the plasma membrane leads to phosphorylation of Src at the tyrosine 530 residue resulting in a reduction of ERK1/2 phosphorylation.

  2. Data suggest that as a natural inhibitor of c-Src kinase, naringin could be an effective candidate for the treatment of melanoma.

  3. deregulation of the Pragmin-Csk axis may induce aberrant cell migration that contributes to tumor invasion and metastasis

  4. Our results do not support association between PTPN22 (zeige PTPN22 Proteine)/CSK and Henoch-Schonlein purpura

  5. Results identify CSK downregulation as a principal driver of SRC (zeige SRC Proteine) activation and castration resistance.

  6. Variant rs1378942 near CSK was nominally associated with systolic blood pressure in a Chinese population.

  7. CSK is the kinase responsible for C-terminal phosphorylation of SRC (zeige SRC Proteine), but not BRK (zeige PTK6 Proteine).

  8. Data indicate that the potent c-Src (zeige SRC Proteine) inhibitors pyrazolo[3,4-d]pyrimidines showed in vivo activity in neuroblastoma (zeige ARHGEF16 Proteine) xenograft model.

  9. Haemophilus ducreyi LspA1 protein inhibits phagocytosis by activation of host CSK.

  10. In Chinese children, no association of CSK rs1378942, MTHFR (zeige MTHFR Proteine) rs1801133, CYP17A1 (zeige CYP17A1 Proteine) rs1004467, STK39 (zeige STK39 Proteine) rs3754777 and FGF5 (zeige FGF5 Proteine) rs16998073 with BP/risk of hypertension.

Mouse (Murine) C-Src tyrosine Kinase (CSK) Interaktionspartner

  1. Csk is a causative gene in the 15q24 locus and regulates blood pressure through Src (zeige SRC Proteine), and these findings provide a novel therapeutic target for the treatment of hypertension

  2. Csk plays an important role, not only in basal signaling, but also in setting the T cell antigen receptor signaling threshold and affinity recognition.

  3. SHIP1 (zeige INPP5D Proteine) and Csk are part of the PSTPIP2 (zeige PSTPIP2 Proteine)-dependent inhibitory network that prevents the development of autoinflammatory disease.

  4. If Cbp enhances the interaction between c-Src and FAK, Cbp could promote c-Src function when lipid rafts are disrupted.

  5. Suggest critical role of Cav1 in modulating cSrc activation, gap junction remodeling, and ventricular arrhythmias.

  6. Differentiation of embryonic stem cells is driven by c-Src (zeige SRC Proteine) is antagonized by c-Yes (zeige YES1 Proteine).

  7. critical role in preventing TCR signaling

  8. It was concluded that c-Src (zeige SRC Proteine) and NADPH oxidase (zeige NOX1 Proteine) components are necessary for redox-mediated production of TNF-alpha (zeige TNF Proteine) following liver ischemia-reperfusion and that hepatocytes play an important role in this process.

  9. Data indicate that chemical rescue of c-Src provided a tool to dissect the spatiotemporal mechanism of activation of the Rap1 guanine exchange factor, C3G, one of the identified potential c-Src substrates that plays a role in focal adhesion signaling.

  10. The Csk pathway appears to be a critical signaling cascade regulating social learning and memory

Cow (Bovine) C-Src tyrosine Kinase (CSK) Interaktionspartner

  1. Dok-4 (zeige DOK4 Proteine) has a role as an anchoring molecule for the tyrosine kinase (zeige TYRO3 Proteine) c-Src (zeige SRC Proteine), and in turn as a regulator of TNF-alpha (zeige TNF Proteine)-mediated ROS (zeige ROS1 Proteine) production and NF-kappaB (zeige NFKB1 Proteine) activation

  2. Src (zeige SRC Proteine) family tyrosine kinases play a central role of arginase and inducible nitric oxide synthase (zeige NOS2 Proteine) in pulmonary artery endothelium.

  3. Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells.

CSK Protein Überblick

Protein Überblick

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).

Alternative names and synonyms associated with CSK

  • c-src tyrosine kinase (CSK)
  • c-src tyrosine kinase (Csk)
  • AW212630 Protein

Bezeichner auf Proteinebene für C-Src tyrosine Kinase Proteine (CSK)

C-Src kinase , protein-tyrosine kinase CYL , tyrosine-protein kinase CSK , p50CSK , protein-tyrosine kinase MPK-2 , C-SRC kinase , protein-tyrosine kinase (CSK) , protein kinase , src kinase

1445 Homo sapiens
12988 Mus musculus
315707 Rattus norvegicus
487649 Canis lupus familiaris
509246 Bos taurus
396396 Gallus gallus
100154110 Sus scrofa
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