CSK Protein (AA 1-450) (GST tag)
(1 reference)Kurzübersicht für CSK Protein (AA 1-450) (GST tag) (ABIN1350517)
Target
Alle CSK Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
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Proteineigenschaft
- AA 1-450
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Aufreinigungstag / Konjugat
- Dieses CSK Protein ist gelabelt mit GST tag.
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Verwendungszweck
- CSK (Human) Recombinant Protein (P01)
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Sequenz
- MSAIQAAWPS GTECIAKYNF HGTAEQDLPF CKGDVLTIVA VTKDPNWYKA KNKVGREGII PANYVQKREG VKAGTKLSLM PWFHGKITRE QAERLLYPPE TGLFLVREST NYPGDYTLCV SCDGKVEHYR IMYHASKLSI DEEVYFENLM QLVEHYTSDA DGLCTRLIKP KVMEGTVAAQ DEFYRSGWAL NMKELKLLQT IGKGEFGDVM LGDYRGNKVA VKCIKNDATA QAFLAEASVM TQLRHSNLVQ LLGVIVEEKG GLYIVTEYMA KGSLVDYLRS RGRSVLGGDC LLKFSLDVCE AMEYLEGNNF VHRDLAARNV LVSEDNVAKV SDFGLTKEAS STQDTGKLPV KWTAPEALRE KKFSTKSDVW SFGILLWEIY SFGRVPYPRI PLKDVVPRVE KGYKMDAPDG CPPAVYEVMK NCWHLDAAMR PSFLQLREQL EHIKTHELHL
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Produktmerkmale
- Human CSK full-length ORF ( NP_004374.1, 1 a.a. - 450 a.a.) recombinant protein with GST-tag at N-terminal.
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Aufreinigung
- in vitro wheat germ expression system
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C-Src tyrosine Kinase (CSK) (AA 1-450) protein (His tag)
CSK Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS
C-Src tyrosine Kinase (CSK) (Active) protein (GST tag,His tag)CSK Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
C-Src tyrosine Kinase (CSK) (Active) protein (GST tag)CSK Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
C-Src tyrosine Kinase (CSK) proteinCSK Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
C-Src tyrosine Kinase (CSK) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)CSK Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Best use within three months from the date of receipt of this protein.
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: "SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91582, (2014) (PubMed).
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- CSK (C-Src tyrosine Kinase (CSK))
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Andere Bezeichnung
- CSK
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Hintergrund
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Full Gene Name: c-src tyrosine kinase
Synonyms: MGC117393 -
Gen-ID
- 1445
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NCBI Accession
- NM_004383
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Pathways
- T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
Target
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