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anti-SHC3 (SHC3) Antikörper

Bezeichnung:
anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 Antikörper (SHC3)
Auf www.antikoerper-online.de finden Sie aktuell 56 SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SHC3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 67 SHC3 Produkte verfügbar.
Synonyme:
N-Shc, NSHC, Rai, ShcC

Meistgesuchte Reaktivitäten zu anti-SHC3 (SHC3) Antikörper

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anti-Human SHC3 Antikörper:

anti-Rat (Rattus) SHC3 Antikörper:

anti-Mouse (Murine) SHC3 Antikörper:

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Am meisten referenzierte anti-SHC3 Antikörper

  1. Human Polyclonal SHC3 Primary Antibody für WB - ABIN2801960 : Liu, Meakin: ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 4 Referenzen für ABIN2801960

  2. Human Monoclonal SHC3 Primary Antibody für IF, IP - ABIN968082 : Conti, Sipione, Magrassi, Bonfanti, Rigamonti, Pettirossi, Peschanski, Haddad, Pelicci, Milanesi, Pelicci, Cattaneo: Shc signaling in differentiating neural progenitor cells. in Nature neuroscience 2001 (PubMed)
    Zeige alle 3 Referenzen für ABIN968082

  3. Human Polyclonal SHC3 Primary Antibody für IHC, ELISA - ABIN1535370 : Nakamura, Sanokawa, Sasaki, Ayusawa, Oishi, Mori: N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway. in Oncogene 1996 (PubMed)
    Zeige alle 2 Referenzen für ABIN1535370

  4. Human Polyclonal SHC3 Primary Antibody für WB - ABIN2786992 : Villanacci, Bassotti, Ortensi, Fisogni, Cathomas, Maurer, Galletti, Salerni, Pelicci: Expression of the Rai (Shc C) adaptor protein in the human enteric nervous system. in Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2008 (PubMed)

Weitere Antikörper gegen SHC3 Interaktionspartner

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Interaktionspartner

  1. High SHC3 expression is associated with glioblastoma.

  2. Rai (ShcC/N-Shc), a member of the family of Shc (zeige SHC1 Antikörper)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.

  3. Polymorphism in RAI (zeige RNH1 Antikörper) and CD3EAP (zeige CD3EAP Antikörper) are associated with outcome of myeloma patients treated with high dose treatment.

  4. amplification of SHC3 and EDG3 (zeige S1PR3 Antikörper) genes suggests that the two proteins co-operate and are important for ependymomas in vivo.

  5. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (zeige SHC1 Antikörper).

  6. ALK (zeige ALK Antikörper)-ShcC signal activation, possibly caused by co-amplification with the N-myc (zeige MYCN Antikörper) gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK (zeige ALK Antikörper) kinase.

  7. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret (zeige RET Antikörper) to the phosphatidylinositol 3-kinase/Akt (zeige AKT1 Antikörper) signaling pathway.

  8. ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (zeige ARHGEF16 Antikörper) cells

  9. The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells.

  10. data suggest that RAI (ShcC/H-Shc (zeige SHC1 Antikörper))is a critical substrate for RET (zeige RET Antikörper) oncoproteins in thyroid carcinomas

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Interaktionspartner

  1. Rai (ShcC/N-Shc), a member of the family of Shc (zeige SHC1 Antikörper)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.

  2. Rai interferes with the TCR signaling cascade one of the earliest steps--recruitment of the initiating kinase ZAP-70 (zeige ZAP70 Antikörper) to the phosphorylated subunit of the TCR/CD3 (zeige CD3E Antikörper) complex.

  3. TrkB (zeige NTRK2 Antikörper)-mediated ERK1/2 (zeige MAPK1/3 Antikörper) activation is impaired in huntingtin (zeige HTT Antikörper) knock-in striatal cells involves reduced p52 (zeige GTF2H4 Antikörper)/p46 (zeige POLDIP3 Antikörper) Shc (zeige SHC1 Antikörper) expression

  4. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (zeige SHC1 Antikörper).

  5. binds the Trk (zeige NTRK1 Antikörper) receptors in a phosphotyrosine-dependent manner via their N-terminal phosphotyrosine binding domain

  6. Rai has a functional neuroprotective role in brain injury, with possible implications in the treatment of stroke

  7. ShcC mediates TrkB (zeige NTRK2 Antikörper)-Ras/MAPK (zeige MAPK1 Antikörper) signaling & regulates NMDA receptor function in the hippocampus via interaction with phosphotyrosines on the receptor subunits. It serves as a modulator of hippocampal synaptic plasticity underlying learning & memory.

  8. ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (zeige ARHGEF16 Antikörper) cells

  9. Expressed in T and B cells; loss of Rai results in breaking of immunological tolerance and development of systemic autoimmunity.

  10. study reports co-localization of adaptor proteins nShc & Grb10 (zeige GRB10 Antikörper), with Kv1.3 (zeige KCNA3 Antikörper) channel in the olfactory bulb neural lamina; BDNF (zeige BDNF Antikörper)-induced current suppression of the Kv1.3 (zeige KCNA3 Antikörper) channel was prevented by both nShc and Grb10 (zeige GRB10 Antikörper)

SHC3 Antigen-Profil

Beschreibung des Gens

may be involved in brain-derived neurotrophic factor signalling during retinal development

Alternative names and synonyms associated with SHC3

  • SHC (Src homology 2 domain containing) transforming protein 3 (SHC3) Antikörper
  • SHC (Src homology 2 domain containing) transforming protein 3 (Shc3) Antikörper
  • src homology 2 domain-containing transforming protein C3 (Shc3) Antikörper
  • N-Shc Antikörper
  • NSHC Antikörper
  • Rai Antikörper
  • ShcC Antikörper

Bezeichner auf Proteinebene für SHC3

SH2 domain protein C3 , SHC-transforming protein 3 , SHC-transforming protein C , neuronal Shc , protein Rai , src homology 2 domain-containing transforming protein C3 , src homology 2 domain-containing-transforming protein C3 , N-Shc

GENE ID SPEZIES
100061926 Equus caballus
53358 Homo sapiens
114858 Rattus norvegicus
476352 Canis lupus familiaris
20418 Mus musculus
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