anti-AXL (AXL) Antikörper

anti-AXL Receptor tyrosine Kinase Antikörper (AXL)
Auf finden Sie aktuell 295 AXL Receptor tyrosine Kinase (AXL) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen AXL Kits (30) und AXL Proteine (20) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 362 AXL Produkte verfügbar.
AI323647, Ark, JTK11, Tyro7, Ufo

Meistgesuchte Reaktivitäten zu anti-AXL (AXL) Antikörper

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anti-Human AXL Antikörper:

anti-Mouse (Murine) AXL Antikörper:

anti-Rat (Rattus) AXL Antikörper:

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Am meisten referenzierte anti-AXL Antikörper

  1. Human Polyclonal AXL Primary Antibody für FACS, IHC (p) - ABIN391878 : Lee, Strunk, Spritz: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. in Oncogene 1993 (PubMed)
    Zeige alle 4 Referenzen für 391878

  2. Human Polyclonal AXL Primary Antibody für EIA, WB - ABIN359786 : Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: A novel putative tyrosine kinase receptor with oncogenic potential. in Oncogene 1991 (PubMed)
    Zeige alle 4 Referenzen für 359786

  3. Human Polyclonal AXL Primary Antibody für EIA, WB - ABIN359784 : OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. in Molecular and cellular biology 1991 (PubMed)
    Zeige alle 4 Referenzen für 359784

  4. Human Polyclonal AXL Primary Antibody für FACS, IHC (p) - ABIN391876 : Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: Putative tyrosine kinases expressed in K-562 human leukemia cells. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Zeige alle 4 Referenzen für 391876

  5. Human Monoclonal AXL Primary Antibody für FACS - ABIN4895642 : Zheng, Hedl, Abraham: TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  6. Human Monoclonal AXL Primary Antibody für FACS - ABIN4895644 : Yumoto, Eber, Wang, Cackowski, Decker, Lee, Nobre, Aguirre-Ghiso, Jung, Taichman: Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow. in Scientific reports 2016 (PubMed)

  7. Mouse (Murine) Monoclonal AXL Primary Antibody für FACS - ABIN4899408 : Fujimori, Grabiec, Kaur, Bell, Fujino, Cook, Svedberg, MacDonald, Maciewicz, Singh, Hussell: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. in Mucosal immunology 2015 (PubMed)

Weitere Antikörper gegen AXL Interaktionspartner

Human AXL Receptor tyrosine Kinase (AXL) Interaktionspartner

  1. we identify PROS1 (zeige PROS1 Antikörper) as a driver of Oral Squamous Cell Carcinoma tumor growth and a modulator of AXL expression

  2. Studies indicate that aberrant AXL receptor tyrosine kinase (AXL) signaling and development of an epithelial-to-mesenchymal transition (EMT (zeige ITK Antikörper)) phenotype underlie resistance of anaplastic lymphoma kinase (ALK (zeige ALK Antikörper) F1174L)-driven neuroblastoma (zeige ARHGEF16 Antikörper) (NB) cells to TAE684 and its derivatives.

  3. Studied axl kinase as a negative regulator of an alveolar epithelial cell phenotype; results found that inhibition of Axl kinase could form epithelial adhesion structure and augment surfactant protein production via the MET of human lung multi-potent cells.

  4. AXL is efficiently and sequentially cleaved by alpha- and gamma-secretases in various types of cancer cell lines. The AXL intracellular domain cleavage product translocates into the nucleus via a nuclear localization sequence that harbored a basic HRRKK motif.

  5. a relationship between AXL and the cellular response to DNA damage whereby abrogation of AXL signaling leads to accumulation of the DNA-damage markers gammaH2AX (zeige H2AFX Antikörper), 53BP1 (zeige TP53BP1 Antikörper), and RAD51 (zeige RAD51 Antikörper).

  6. Small molecule and antibody inhibitors of AXL and MER (zeige MERTK Antikörper) have recently been described, and some of these have already entered clinical trials. The optimal design of treatment strategies to maximize the clinical benefit of these AXL and MER (zeige MERTK Antikörper) targeting agents are discussed in relation to the different cancer types and the types of resistance encountered.

  7. our results demonstrate that AR can promote melanoma metastasis via altering the miRNA-539-3p/USP13 (zeige USP13 Antikörper)/MITF (zeige MITF Antikörper)/AXL signal and targeting this newly identified signal with AR degradation enhancer ASC (zeige PYCARD Antikörper)-J9 may help us to better suppress the melanoma metastasis.

  8. AXL can be an effective therapeutic target in combination with targeted therapy such as PARP (zeige COL11A2 Antikörper) inhibitors in several different malignancies.

  9. AXL/TAZ (zeige TAZ Antikörper)/YAP (zeige YAP1 Antikörper) expression is associated with poor prognosis in male breast cancer patients.

  10. High AXL expression is associated with Paclitaxel resistance in breast Cancers.

Mouse (Murine) AXL Receptor tyrosine Kinase (AXL) Interaktionspartner

  1. Both Axl+/- and Axl-/- suckling mice supported the replication of Zika virus.

  2. reciprocal activation of Axl and Mer (zeige ERH Antikörper) receptor tyrosine kinases has a major impact on the outcome of renal inflammation.

  3. Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.

  4. Axl, Mertk (zeige MERTK Antikörper) and Tyro3 (zeige TYRO3 Antikörper) receptors are not required for Zika virus entry and infection.

  5. Axl plays an essential role in the regulation of NK cell development as well as natural killer effector function.

  6. Matrix metalloproteases ADAM10 (zeige ADAM10 Antikörper) and TACE (ADAM17 (zeige ADAM17 Antikörper)) cleave AXL receptor tyrosine kinase (Axl) in lupus-prone leukocytes.

  7. Gas6 (zeige GAS6 Antikörper)/Axl and Akt (zeige AKT1 Antikörper)/FoxO1a (zeige FOXO1 Antikörper) were involved in protective effects of testosterone on VSMCs senescence and collagen synthesis.

  8. Axl allows specific identification of airway macrophages, and that its expression is critical for macrophage functional compartmentalization in the airspaces or lung interstitium.

  9. results establish TAM (zeige CCNA1 Antikörper) receptors as both controllers of microglial physiology and potential targets for therapeutic intervention in central nervous system disease

  10. These results suggest that TAM (zeige CCNA1 Antikörper) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.

Cow (Bovine) AXL Receptor tyrosine Kinase (AXL) Interaktionspartner

  1. activation of receptor tyrosine kinase (zeige RET Antikörper) Axl inhibits the osteogenic differentiation of vascular pericytes.

AXL Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with AXL

  • AXL receptor tyrosine kinase (AXL) Antikörper
  • AXL receptor tyrosine kinase (Axl) Antikörper
  • Axl receptor tyrosine kinase (Axl) Antikörper
  • AI323647 Antikörper
  • Ark Antikörper
  • JTK11 Antikörper
  • Tyro7 Antikörper
  • Ufo Antikörper

Bezeichner auf Proteinebene für AXL

AXL oncogene , AXL transforming sequence/gene , tyrosine-protein kinase receptor UFO , adhesion-related kinase , ufo oncogene homolog

100064907 Equus caballus
558 Homo sapiens
26362 Mus musculus
308444 Rattus norvegicus
484490 Canis lupus familiaris
100144875 Sus scrofa
516598 Bos taurus
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