Hepatitis A Virus Cellular Receptor 2 Proteine (HAVCR2)

Auf www.antikoerper-online.de finden Sie aktuell 41 Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Proteine von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Hepatitis A Virus Cellular Receptor 2 Antikörper (216) und Hepatitis A Virus Cellular Receptor 2 Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 279 Hepatitis A Virus Cellular Receptor 2 Produkte verfügbar.
HAVcr-2, HAVCR2, KIM-3, MGC140131, TIM-3, tim3, TIMD-3, Timd3
alle Proteine anzeigen Gen GeneID UniProt
HAVCR2 84868 Q8TDQ0
HAVCR2 171285 Q8VIM0
HAVCR2 363578  

Hepatitis A Virus Cellular Receptor 2 Proteine (HAVCR2) nach Spezies

Weitere Proteine zu Hepatitis A Virus Cellular Receptor 2 Interaktionspartnern

Cow (Bovine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. The Tim-3/Gal-9 (zeige LGALS9 Proteine) pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.

Human Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. Tim3/Gal-9 (zeige LGALS9 Proteine) alleviates the inflammation of TAO patients via suppressing Akt (zeige AKT1 Proteine)/NF-kappaB (zeige NFKB1 Proteine) signaling pathway.

  2. this study shows that severe aplastic anemia untreated patients have lower TIM-3 expression on NK cells and CD56dim NK subsets compared with normal controls, and are correlated with the severity of pancytopenia of SAA (zeige SAA1 Proteine)

  3. We conclude that Tim-3 is a biomarker of dysfunctional plasmacytoid dendritic cells

  4. The present study defines the minimal TIM-3 promoter region and demonstrates its interaction with c-Jun (zeige JUN Proteine) during TIM-3 transcription in CD4 (zeige CD4 Proteine)(+) T cells.

  5. Our findings establish intratumoral Tim-3(+)PD1 (zeige PDCD1 Proteine)(+)CD8 (zeige CD8A Proteine)(+) T cells as critical mediators of an aggressive phenotype in RCC (zeige XRCC1 Proteine).

  6. Osteosarcoma patients with higher Tim-3 had relatively lower survival. Multivariate analyses for overall survival revealed that high serum soluble Tim-3 level was an independent prognostic factor for osteosarcoma

  7. urther analyses revealed that the levels of Tim-3 on CD4 (zeige CD4 Proteine)+ T cells and CD8 (zeige CD8A Proteine)+ T cells exhibited different expression patterns in terms of localization depending on pathological category of prostate cancer and metastasis. Immunohistochemical analysis revealed that positive staining of Tim-3 in prostate cancer but little or no staining of Tim-3 was observed in benign prostate hyperplasia epithelium.

  8. this review discusses the recent findings on Tim-3, the role it plays in regulating immune responses in different cell types and the rationale for targeting Tim-3 for effective cancer immunotherapy

  9. The -1516G > T, -574G > T and +4259T > G SNPs within TIM-3 gene might play an important role as a genetic risk factor in the pathogenesis of ET.

  10. this study shows that that Tim-3 expression defines a subpopulation of PD-1 (zeige PDCD1 Proteine)+ exhausted NY-ESO-1 (zeige CTAG1B Proteine)-specific CD8 (zeige CD8A Proteine)+ T cell and PD-1 (zeige PDCD1 Proteine)+Tim-3+ CD8 (zeige CD8A Proteine)+ T cells represented the largest subset of NY-ESO-1 (zeige CTAG1B Proteine)-specific CD8 (zeige CD8A Proteine)+ T cells in gastric cancer patients

Mouse (Murine) Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Interaktionspartner

  1. demonstrated that both IL-10 (zeige IL10 Proteine) and TGF-beta (zeige TGFB1 Proteine) upregulated TIM-3 surface expression on dendritic cells via a common signaling pathway that involved sequential activation of c-Src (zeige SRC Proteine) and Bruton's tyrosine kinase (zeige BTK Proteine)

  2. Methylation level of the TIM-3 promoter gradually decreased after each round of T-cell polarization, and this decrease was inversely correlated with TIM-3 expression.

  3. in mice, TIM-3 is not essential for development of HDM (zeige HDAC3 Proteine)-induced acute or chronic allergic airway inflammation, although it appears to be involved in reduced lymphocyte recruitment during HDM (zeige HDAC3 Proteine)-induced chronic allergic airway inflammation.

  4. Authors found that a CD8 (zeige CD8A Proteine)(+) T-cell population with age-associated exhaustion was distinguishable by its expression of Tim-3.

  5. TIM4 (zeige TIMD4 Proteine) binds TIM3 on the surface of polarized Th1 (zeige HAND1 Proteine) cells to induce Th1 (zeige HAND1 Proteine) cell apoptosis, which may contribute to the development of Th2-dominant immune disorders.

  6. The Gal-9 (zeige LGALS9 Proteine)/Tim-3 signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.

  7. TIM-3 expression by NK cells and gamma/delta T cells is similar in the peripheral and decidual immune cells from pregnant mice.

  8. Tim-3 acts at a receptor-proximal point to enhance Lyn (zeige LYN Proteine) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI (zeige FCER1A Proteine) ligation.

  9. Our data indicate that Tim-3 expression on NK cells is regulated by T-bet, and that Tim-3 levels correlate with advanced stages of gastric cancer

  10. TIM-3 plays a role in regulating the uterine natural killer cells and contributes to the maintenance of tolerance at the feto-maternal interface.

Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Alternative names and synonyms associated with Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

  • hepatitis A virus cellular receptor 2 (HAVCR2)
  • hepatitis A virus cellular receptor 2 (Havcr2)
  • HAVcr-2 Protein
  • HAVCR2 Protein
  • KIM-3 Protein
  • MGC140131 Protein
  • TIM-3 Protein
  • tim3 Protein
  • TIMD-3 Protein
  • Timd3 Protein

Bezeichner auf Proteinebene für HAVCR2

hepatitis A virus cellular receptor 2 , T cell immunoglobulin mucin 3 , T cell immunoglobulin mucin-3 , T-cell immunoglobulin and mucin domain-containing protein 3 , T-cell membrane protein 3 , kidney injury molecule-3 , HAVcr-2 , T-cell immunoglobulin and mucin domain containing 3 , TIMD-3 , hepatitis A virus cellular receptor 2 homolog , TIM-3

462219 Pan troglodytes
768047 Bos taurus
84868 Homo sapiens
171285 Mus musculus
363578 Rattus norvegicus
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