8-Oxoguanine DNA Glycosylase (OGG1) protein (HIS)

Name: 8-Oxoguanine DNA Glycosylase (OGG1)

Synonyme: HMMH, MUTM, OGH1, HOGG1, OGG1, ogg1, 8-OXOGUANINE-DNA GLYCOSYLASE 1, F8K7.14, F8K7_14, 19.m02329, Tb04.1H19.930

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN667178

Produktbeschreibung

Produktmerkmale: OGG1, 1-345aa, Human, His tag, E.coli

Format: Liquid

Beschreibung: OGG1, also known as 8-oxoguanine glycosylase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS). It has a beta lyase activity that nicks DNA 3' to the lesion. Recombinant human OGG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: HMMH, HOGG1, MUTM, OGH1, AP lyase, 8-oxoguanine DNA glycosylase 1. NCBI no.: AAH00657

Molekulargewicht: 41.2 kDa(368aa), confirmed by MALDI-TOF

Anwendungen

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Reinheit: > 90% by SDS - PAGE

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) Containing 100 mM NaCl, 40% Glycerol

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

8-Oxoguanine DNA Glycosylase (OGG1) protein (HIS)