WIF1 Protein (AA 29-379) (His tag)

Produktnummer ABIN622178

Dieses Recombinant WIF1-Protein wird in not_set produziert.

Kurzübersicht für WIF1 Protein (AA 29-379) (His tag) (ABIN622178)

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Protein-Typ: Recombinant

Spezies: Human

Wirt: Bitte anfragen

Reinheit: > 80.0 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 29-379

Aufreinigungstag / Konjugat: Dieses WIF1 Protein ist gelabelt mit His tag.

Sequenz: ADLGPPQEES LYLWIDAHQA RVLIGFEEDI LIVSEGKMAP FTHDFRKAQQ RMPAIPVNIH SMNFTWQAAG QAEYFYEFLS LRSLDKGIMA DPTVNVPLLG TVPHKASVVQ VGFPCLGKQD GVAAFEVDVI VMNSEGNTIL KTPQNAIFFK TCQQAECPGG CRNGGFCNER RICECPDGFH GPHCEKALCT PRCMNGGLCV TPGFCICPPG FYGVNCDKAN CSTTCFNGGT CFYPGKCICP PGLEGEQCEI SKCPQPCRNG GKCIGKSKCK CSKGYQGDLC SKPVCEPGCG AHGTCHEPNK CQCQEGWHGR HCNKRYEASL IHALRPAGAQ LRQHTPSLKK AEERRDPPES NYIWSGRLVP RG

Produktmerkmale: Recombinant Human WNT Inhibitory Factor 1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The WIF1 protein solution contains 1X PBS pH 7.4, 10% glycerol and 1mM PMSF.

Lagerung: 4 °C

Antigendetails

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Andere Bezeichnung: WNT Inhibitory Factor 1

Hintergrund: WIF1 produced in Hi-5 cells is a single, glycosylated polypeptide chain containing 369 AA (29-379 AA) and having a molecular mass of 40.5 kDa, (48 kDa on SDS-PAGE). WIF1 is fused to 16 AA His Tag at C-Terminus and purified by proprietary chromatographic techniques. Introduction: WIF1 binds to wnt proteins and inhibits their activities. WIF1 plays a role in mesoderm segmentation. WNT proteins are extracellular signaling molecules that take part in the control of embryonic development and cancer. WIF1 protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. WIF1 takes part in mesoderm segmentation. WIF1 protein is found to be present in fish, amphibia and mammals. WIF1 is a recurrent target in human salivary gland oncogenesis. Downregulation of WIF1 takes part in the development and progression of pleomorphic adenomas. WIF1 is a tumor suppressor, specifically in nonfunctioning pituitary tumors. Synonyms: WIF1, WIF-1, Wnt inhibitory factor 1.

Pathways: WNT Signalweg, Positive Regulation of fat Cell Differentiation