A synthetic peptide for use as a blocking control in assays to test for specificity of H2 AFY2 antibody, Alternative Names: H2AFY2 control peptide, H2AFY2 antibody Blocking Peptide, Anti-H2AFY2 Blocking Peptide, H2A Histone Y2 Blocking Peptide, macroH2A2 Blocking Peptide, H2AF, HAF-2, HAF 2, HAF-2 Blocking Peptide, HAF 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
H2AFY2
(H2A Histone Family, Member Y2 (H2AFY2))
Hintergrund
H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.