anti-PAK2 (PAK2) Antikörper

anti-P21-Activated Kinase 2 Antikörper (PAK2)
Auf finden Sie aktuell 184 P21-Activated Kinase 2 (PAK2) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PAK2 Proteine (14) und PAK2 Kits (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 225 PAK2 Produkte verfügbar.
5330420P17Rik, A130002K10Rik, AI836325, cb422, D16Ertd269e, gamma-PAK, kinase, mKIAA4182, PAK-2, pak2, Pak3, PAK65, PAKgamma, PAKI, si:dz198m22.1, wu:fb71h01, zgc:91798

Meistgesuchte Reaktivitäten zu anti-PAK2 (PAK2) Antikörper

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anti-Human PAK2 Antikörper:

anti-Mouse (Murine) PAK2 Antikörper:

anti-Rat (Rattus) PAK2 Antikörper:

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Am meisten referenzierte anti-PAK2 Antikörper

  1. Human Polyclonal PAK2 Primary Antibody für IHC (p), WB - ABIN2476049 : Rudel, Bokoch: Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. in Science (New York, N.Y.) 1997 (PubMed)
    Zeige alle 3 Referenzen für 2476049

  2. Human Monoclonal PAK2 Primary Antibody für ICC, IHC - ABIN969338 : Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: A novel role for p21-activated protein kinase 2 in T cell activation. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Zeige alle 2 Referenzen für 969338

  3. Human Polyclonal PAK2 Primary Antibody für EIA, IHC (p) - ABIN360318 : Benner, Dennis, Masaracchia: Activation of an S6/H4 kinase (PAK 65) from human placenta by intramolecular and intermolecular autophosphorylation. in The Journal of biological chemistry 1995 (PubMed)
    Zeige alle 2 Referenzen für 360318

  4. Human Polyclonal PAK2 Primary Antibody für IHC (p), WB - ABIN318772 : Roig, Traugh: Cytostatic p21 G protein-activated protein kinase gamma-PAK. in Vitamins and hormones 2001 (PubMed)
    Zeige alle 2 Referenzen für 318772

  5. Human Polyclonal PAK2 Primary Antibody für IHC (p), WB - ABIN392433 : Martin, Bollag, McCormick, Abo: A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. in The EMBO journal 1995 (PubMed)
    Zeige alle 2 Referenzen für 392433

  6. Human Polyclonal PAK2 Primary Antibody für IP, WB - ABIN253074 : Qu, Misaghi, Izrael-Tomasevic, Newton, Gilmour, Lamkanfi, Louie, Kayagaki, Liu, Kömüves, Cupp, Arnott, Monack, Dixit: Phosphorylation of NLRC4 is critical for inflammasome activation. in Nature 2012 (PubMed)

  7. Human Polyclonal PAK2 Primary Antibody für IHC, ELISA - ABIN1532071 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

Weitere Antikörper gegen PAK2 Interaktionspartner

Zebrafish P21-Activated Kinase 2 (PAK2) Interaktionspartner

  1. EphrinB ligands B2a and B3b, the Ephb4a (zeige EPHB4 Antikörper) receptor and the Pak2a kinase are required for the development of pharyngeal pouches and the segmentation of the posterior facial skeleton.

  2. Essential in vivo role for betaPix (zeige ARHGEF7 Antikörper) and Pak2a during embryonic development and a previously unrecognized pathway specifically involved in cerebrovascular stabilization. [BetaPix (zeige ARHGEF7 Antikörper) AND Pak2a]

  3. Data provide evidence for a critical function of Pak2 in vascular integrity and demonstrate a severe disease phenotype resulting from loss of Pak2 function.

Human P21-Activated Kinase 2 (PAK2) Interaktionspartner

  1. We found that overexpression of miR (zeige MLXIP Antikörper)-137 inhibited the proliferation of melanoma cells, which could be phenocopied by knockdown of PAK2 using siRNAs.

  2. PAK2 is a direct effector of TSC1 (zeige TSC1 Antikörper)-TSC2 (zeige TSC2 Antikörper)-RHEB (zeige RHEB Antikörper) signaling and a new target for rational drug therapy in TSC (zeige SLC12A3 Antikörper).

  3. Nef exploits PAK2 in a stepwise mechanism in which its kinase activity cooperates with an adaptor function for the exocyst complex to inhibit host cell actin dynamics.

  4. Cytoplasmic Pak2 may promote cell proliferation in normal endometrium during menstrual cycle.

  5. Further analyses show that HDAC6 (zeige HDAC6 Antikörper) may promote growth of GBM cells through inhibition of SMAD2 (zeige SMAD2 Antikörper) phosphorylation to downregulate p21 (zeige CDKN1A Antikörper)

  6. Pak1 (zeige PAK1 Antikörper) and Pak2 counteract centrosome separation in a kinase-dependent manner.

  7. Findings indicate that repression of microRNA miR (zeige MLXIP Antikörper)-134 and consequent up-regulation of p21-activated kinase 2 (Pak2) might contribute to paclitaxel resistance.

  8. Inhibition of PAK activation at late G2-phase centrosomes caused by Rac1 inactivation coincides with impeded activation of Aurora A (zeige AURKA Antikörper) and the CyclinB (zeige CCNB1 Antikörper)/Cdk1 (zeige CDK1 Antikörper) complex and delayed mitotic entry.

  9. Data show that group I p21 (zeige CDKN1A Antikörper)-activated kinases (Paks) Pak1 (zeige PAK1 Antikörper) and Pak2 were much more abundant than Pak3 in meningioma.

  10. Results identified Pak2 as a possibly important mediator of ovarian cancer cell migration on extracellular matrix.

Mouse (Murine) P21-Activated Kinase 2 (PAK2) Interaktionspartner

  1. These results identify Pak1 (zeige PAK1 Antikörper) and Pak2 as redundant regulators of myoblast differentiation in vitro and in vivo and as components of the promyogenic Ncad (zeige CDH2 Antikörper)/Cdo (zeige CDO1 Antikörper)/Cdc42 (zeige CDC42 Antikörper) signaling pathway.

  2. PAK-mediated phosphorylation of PKD1 at Ser203 triggers its membrane dissociation and subsequent entry into the nucleus, thereby regulating the phosphorylation of PKD1 nuclear targets, including class IIa histone deacetylases.

  3. Data indicate that resveratrol treatment inhibits neuronal glucose uptake via P21-activated kinase 2 (PAK2).

  4. Mechanistic insights into the role of Pak2 in hematopoietic stem cells migration and homing.

  5. Pak2 disruption decreased the survival and proliferation of multicytokine stimulated immature progenitors.

  6. The data suggest that Pak2 controls thymic Natural Killer T-cell development by providing a signal that links Egr2 (zeige EGR2 Antikörper) to induce PLZF (zeige ZBTB16 Antikörper), in part by regulating signaling lymphocyte activation molecule (zeige SLAMF1 Antikörper) 6 expression.

  7. In adult endothelial cells, Pak2 depletion leads to severe apoptosis and acute angiogenesis defects, and in adult mice, endothelial Pak2 deletion leads to increased vascular permeability.

  8. Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance

  9. Failure to induce proper actin cytoskeletal remodeling impaired PLCgamma1 and Erk1/2 signaling in the absence of Pak2, uncovering the critical function of Pak2 as an essential regulator that governs the actin cytoskeleton-dependent signaling

  10. thrombin (zeige F2 Antikörper) induces monocyte/macrophage migration via PAR1 (zeige F2R Antikörper)-Galpha12 (zeige GNA12 Antikörper)-dependent Pyk2 (zeige PTK2B Antikörper)-mediated Gab1 (zeige GAB1 Antikörper) and p115 RhoGEF (zeige ARHGEF1 Antikörper) interactions, leading to Rac1- and RhoA (zeige RHOA Antikörper)-targeted Pak2 activation.

Cow (Bovine) P21-Activated Kinase 2 (PAK2) Interaktionspartner

  1. Basement membrane proteins promote PAK2 Ser (zeige SIGLEC1 Antikörper)-20 phosphorylation through enhanced eNOS (zeige NOS3 Antikörper) activation and NO production.

PAK2 Antigen-Profil

Beschreibung des Gens

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Alternative names and synonyms associated with PAK2

  • p21 (CDKN1A)-activated kinase 2a (pak2a) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 2 (pak2) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 2 (Pak2) Antikörper
  • 5330420P17Rik Antikörper
  • A130002K10Rik Antikörper
  • AI836325 Antikörper
  • cb422 Antikörper
  • D16Ertd269e Antikörper
  • gamma-PAK Antikörper
  • kinase Antikörper
  • mKIAA4182 Antikörper
  • PAK-2 Antikörper
  • pak2 Antikörper
  • Pak3 Antikörper
  • PAK65 Antikörper
  • PAKgamma Antikörper
  • PAKI Antikörper
  • si:dz198m22.1 Antikörper
  • wu:fb71h01 Antikörper
  • zgc:91798 Antikörper

Bezeichner auf Proteinebene für PAK2

p21 (CDKN1A)-activated kinase 2 , p21-activated kinase 2 , redhead , rhd , serine/threonine-protein kinase PAK 2 , p21 activated kinase 2 , PAK-2 , S6/H4 kinase , gamma-PAK , p58 , p21-activated kinase I , p21-activated protein kinase I

266749 Danio rerio
399090 Xenopus laevis
460965 Pan troglodytes
5062 Homo sapiens
224105 Mus musculus
29432 Rattus norvegicus
513673 Bos taurus
612814 Canis lupus familiaris
424860 Gallus gallus
100009535 Oryctolagus cuniculus
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