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Navigieren Sie durch unsere anti-MAP2K2 (MAP2K2) Antikörper

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 2 Antikörper (MAP2K2)
Auf www.antikoerper-online.de finden Sie aktuell 255 Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP2K2 Proteine (18) und MAP2K2 Kits (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 300 MAP2K2 Produkte verfügbar.
Synonyme:
AA589381, ATMKK2, CFC4, F27B13.50, F27B13_50, MAP KINASE KINASE 1, MAP kinase kinase 2, MAPKK2, MEK2, MK1, MK2, MKK2, PRKMK2

Meistgesuchte Reaktivitäten zu anti-MAP2K2 (MAP2K2) Antikörper

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Am meisten referenzierte anti-MAP2K2 Antikörper

  1. Human Polyclonal MAP2K2 Primary Antibody für IHC (p), WB - ABIN1881526 : Burroughs, Oh, Barrett, DiAugustine et al.: Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ... in Molecular cancer research : MCR 2003 (PubMed)
    Zeige alle 5 Referenzen für ABIN1881526

  2. Chicken Monoclonal MAP2K2 Primary Antibody für IHC (f), IF - ABIN967845 : Crews, Alessandrini, Erikson: The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. in Science (New York, N.Y.) 1992 (PubMed)
    Zeige alle 5 Referenzen für ABIN967845

  3. Human Polyclonal MAP2K2 Primary Antibody für IHC (p), WB - ABIN197106 : Alessi, Saito, Campbell, Cohen, Sithanandam, Rapp, Ashworth, Marshall, Cowley: Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. in The EMBO journal 1994 (PubMed)
    Zeige alle 2 Referenzen für ABIN197106

  4. Human Polyclonal MAP2K2 Primary Antibody für IHC, ELISA - ABIN1531905 : Rosen, Ginty, Weber, Greenberg: Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. in Neuron 1994 (PubMed)
    Zeige alle 2 Referenzen für ABIN1531905

  5. Human Polyclonal MAP2K2 Primary Antibody für EIA, IHC (p) - ABIN360373 : Tran, Maurer, Nagamine: Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2. in Molecular and cellular biology 2003 (PubMed)
    Zeige alle 2 Referenzen für ABIN360373

  6. Chicken Polyclonal MAP2K2 Primary Antibody für IHC, WB - ABIN2783573 : Adjei, Cohen, Franklin, Morris, Wilson, Molina, Hanson, Gore, Chow, Leong, Maloney, Gordon, Simmons, Marlow, Litwiler, Brown, Poch, Kane, Haney, Eckhardt: Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)

Weitere Antikörper gegen MAP2K2 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Interaktionspartner

  1. Data show that mitogen-activated protein kinase (zeige MAPK1 Antikörper) kinases MEK1 (zeige MAP2K1 Antikörper)/2 inhibitor pimasertib (MEKI) sensitized the cells to apoptosis through its ability to promote a G1 cell cycle arrest.

  2. the purpose of this paper was to investigate MAPK (zeige MAPK1 Antikörper) downstream signalling molecules in Natural killer cell phenotypes from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.

  3. at clinically relevant concentrations, cDDP binds to and inhibits MEK1 (zeige MAP2K1 Antikörper)/2 and both the binding and inhibitory activity are related to its interaction with Cu bound to MEK1 (zeige MAP2K1 Antikörper)/2

  4. Endocytosis separates EGF (zeige EGF Antikörper) receptors from endogenous fluorescently labeled HRas (zeige HRAS Antikörper) and diminishes receptor signaling to MAP kinases in endosomes.

  5. MEK1 (zeige MAP2K1 Antikörper) levels are upregulated at transcriptional level whereas MEK2 levels are downregulated at posttranslational level.

  6. MEK1/2 inhibitor trametinib showed similar PFS and a response rate as docetaxel in patients with previously treated KRAS-mutant-positive non-small cell lung carcinoma.

  7. We report on a fourth familial case with transmission of CFC (zeige PTPN11 Antikörper) syndrome from father to son due to a novel heterozygous sequence change c.376A>G (p.N126D) in exon 3 of MEK2 gene.

  8. MK2 (zeige KCNA2 Antikörper) attenuates dendritic cell-mediated Th1 (zeige TH1L Antikörper) differentiation and autoimmune encephalomyelitis.

  9. We documented three novel mutations in the BRAF (zeige BRAF Antikörper) gene in cardio-facio-cutaneous syndrome patients and correlated clinical findings with causative mutations in the BRAF (zeige BRAF Antikörper) or MEK1 (zeige MAP2K1 Antikörper)/MEK2 genes

  10. CCR7 (zeige CCR7 Antikörper) can also promote survival of mDCs through a novel MEK1 (zeige MAP2K1 Antikörper)/2-ERK1/2 (zeige MAPK1/3 Antikörper)-AMPK (zeige PRKAA1 Antikörper) signaling axis.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Interaktionspartner

  1. MEK1 (zeige MAP2K1 Antikörper) and MEK2 can substitute for each other but a minimum amount of MEK (zeige MDK Antikörper) is critical for placenta development and embryo survival

  2. MK2 (zeige KCNA2 Antikörper)/3 cascade plays a strategic role in controlling synaptic plasticity and cognition.

  3. MK2 (zeige KCNA2 Antikörper) attenuates dendritic cell-mediated Th1 (zeige HAND1 Antikörper) differentiation and autoimmune encephalomyelitis.

  4. analysis of p38 (zeige CRK Antikörper)-MK2 (zeige KCNA2 Antikörper)-activated Rsk (zeige RPS6KA1 Antikörper) signaling in toll (zeige TLR4 Antikörper)-like receptor-stimulated dendritic cells

  5. both MEK1 (zeige MAP2K1 Antikörper) and MEK2 have crucial roles in the integration of mesenchymal and epithelial signals essential for the development of the entire respiratory tract

  6. MK2 (zeige KCNA2 Antikörper) is responsible for resistance of p53 (zeige TP53 Antikörper)-deficient tumors to cisplatin

  7. MK2 (zeige KCNA2 Antikörper) plays a critical role in the development of apoptosis.

  8. rapamycin treatment led to an increased MKP1 (zeige DUSP1 Antikörper) expression in BMDM from WT but failed to do so in BMDMs lacking the AKT1 (zeige AKT1 Antikörper) isoform or MEK1 (zeige MAP2K1 Antikörper) and MEK2.

  9. review focuses on the role of the MEK1 (zeige MAP2K1 Antikörper) and MEK2 kinases in the development of extraembryonic tissues and in the formation of the placenta

  10. AT(2)R-mediated eNOS (zeige NOS3 Antikörper) NO production and vasorelaxation through a MEK (zeige MDK Antikörper) pathway are enhanced in aortas from db/db (zeige LEPR Antikörper) mice.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Interaktionspartner

  1. the AtMKK2-AtMPK10 (zeige MAPK10 Antikörper) MAPK (zeige MAPK1 Antikörper) module regulates leaf venation complexity by altering polar auxin transport efficiency

  2. Treatment of Arabidopsis with a membrane rigidifier, DMSO, causes MPK4 (zeige MAPK4 Antikörper) activation concomitantly with MEKK1 (zeige MAP3K1 Antikörper) and MKK2 phosphorylation.

  3. Ca(2 (zeige CA2 Antikörper)+) signaling occurred upstream of the MEKK1 (zeige MAP3K1 Antikörper)-MKK2 pathway. MEKK1 (zeige MAP3K1 Antikörper) was phosphorylated by calcium/calmodulin (zeige CALM Antikörper)-regulated receptor-like kinase (CRLK1), which suggested that CRLK1 is one of candidates located upstream of MEKK1 (zeige MAP3K1 Antikörper).

  4. Data indicate that MEKK2 (zeige MAP3K2 Antikörper) is required for the mekk1 (zeige MAP3K1 Antikörper), mkk1 (zeige MAP2K1 Antikörper) mkk2, and mpk4 (zeige MAPK4 Antikörper) autoimmune phenotypes.

  5. Data suggest that the MEKK1 (zeige MAP3K1 Antikörper)-MKK1 (zeige MAP2K1 Antikörper)/MKK2-MPK4 (zeige MAPK4 Antikörper) kinase cascade negatively regulates MEKK2 (zeige MAP3K2 Antikörper) and activation of MEKK2 (zeige MAP3K2 Antikörper) triggers SUMM2-mediated immune responses.

  6. Data indicate that MKK2 plays a role in abiotic stress tolerance and plant disease resistance.

  7. double loss-of-function mutant (mkk1 (zeige MAP2K1 Antikörper)/2) of MKK1 (zeige MAP2K1 Antikörper) and MKK2 is shown to have marked phenotypes in development and disease

  8. Activation of MPK4 (zeige MAPK4 Antikörper) by flg22 is impaired in the mkk1 (zeige MAP2K1 Antikörper) mkk2 double mutants, suggesting that MKK1 (zeige MAP2K1 Antikörper) and MKK2 function together with MPK4 (zeige MAPK4 Antikörper) and MEKK1 (zeige MAP3K1 Antikörper) in a MAP kinase (zeige MAPK1 Antikörper) cascade to negatively regulate innate immune responses in plants.

MAP2K2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

Alternative names and synonyms associated with MAP2K2

  • mitogen activated protein kinase kinase 2 (Map2k2) Antikörper
  • mitogen-activated protein kinase kinase 2 (MAP2K2) Antikörper
  • mitogen-activated protein kinase kinase 2 (Map2k2) Antikörper
  • mitogen-activated protein kinase kinase 2 (MKK2) Antikörper
  • AA589381 Antikörper
  • ATMKK2 Antikörper
  • CFC4 Antikörper
  • F27B13.50 Antikörper
  • F27B13_50 Antikörper
  • MAP KINASE KINASE 1 Antikörper
  • MAP kinase kinase 2 Antikörper
  • MAPKK2 Antikörper
  • MEK2 Antikörper
  • MK1 Antikörper
  • MK2 Antikörper
  • MKK2 Antikörper
  • PRKMK2 Antikörper

Bezeichner auf Proteinebene für MAP2K2

ERK activator kinase 2 , MAP kinase kinase 2 , MAPK/ERK kinase 2 , MAPKK 2 , MEK 2 , MEK2 , dual specificity mitogen-activated protein kinase kinase 2 , mitogen-activated protein kinase kinase 2, p45 , MAP kinase/Erk kinase , mitogen activated protein kinase kinase 2 , protein kinase, mitogen activated, kinase 2, p45 , dual specificity mitogen activated protein kinase kinase 2 , mitogen-activated protein kinase kinase type 2

GENE ID SPEZIES
58960 Rattus norvegicus
5605 Homo sapiens
26396 Mus musculus
611939 Canis lupus familiaris
396349 Gallus gallus
510434 Bos taurus
829103 Arabidopsis thaliana
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