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anti-Human BCL2 Antikörper:
anti-Rat (Rattus) BCL2 Antikörper:
anti-Mouse (Murine) BCL2 Antikörper:
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Human Polyclonal BCL2 Primary Antibody für ELISA, WB - ABIN3042814
Zong, Li, Lin, Hou, Ma: Lipoxin A4 pretreatment mitigates skeletal muscle ischemia-reperfusion injury in rats. in American journal of translational research 2017
Show all 79 Pubmed References
Human Monoclonal BCL2 Primary Antibody für ICC, IHC (fro) - ABIN3044481
Jiang, Li, Zhou, Wang, Zhang, Wang: Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways. in International journal of molecular medicine 2014
Show all 91 Pubmed References
Human Polyclonal BCL2 Primary Antibody für IF, IHC (p) - ABIN388095
Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010
Show all 19 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IHC (fro), FACS - ABIN967312
Batistatou, Merry, Korsmeyer, Greene: Bcl-2 affects survival but not neuronal differentiation of PC12 cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1993
Show all 13 Pubmed References
Mouse (Murine) Monoclonal BCL2 Primary Antibody für FM, IHC (fro) - ABIN967441
Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991
Show all 10 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IHC (f), IHC (fro) - ABIN967322
Krajewski, Tanaka, Takayama, Schibler, Fenton, Reed: Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. in Cancer research 1993
Show all 7 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IHC (f), IHC (fro) - ABIN967321
Pezzella, Jones, Ralfkiaer, Ersbøll, Gatter, Mason: Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma. in British journal of cancer 1992
Show all 7 Pubmed References
Human Polyclonal BCL2 Primary Antibody für IF (p), IHC (p) - ABIN707156
Wang, Ma, Su: NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. in Biological trace element research 2013
Show all 6 Pubmed References
Dog (Canine) Polyclonal BCL2 Primary Antibody für IHC, IHC (p) - ABIN4283360
Chopra, Ray, Dwivedi, Tiwari, Singh, Singh, Kushwaha, Jahan, Pandey, Gupta, Chaturvedi, Pant, Ray, Gupta: Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line. in Biomaterials 2016
Show all 6 Pubmed References
Human Monoclonal BCL2 Primary Antibody für IP, IHC - ABIN222984
Cordiali-Fei, Ardigo, Mastroianni, Giuliani, D Agosto, Bordignon, Trento, Vento, Berardesca: Serum cytokines and biohumoral immunological characterization of psoriatic patients in long term etanercept treatment. in International journal of immunopathology and pharmacology 2008
Show all 6 Pubmed References
These findings uncover a novel mechanism through which mitochondrial PKM2 phosphorylates Bcl2 and inhibits apoptosis directly.
Study reveals a previously unrecognized synergism between ETV6 (zeige ETV6 Antikörper)/RUNX1 (zeige RUNX1 Antikörper) and BCL2 impacting on malignant disease and autoimmunity.
beta-asarone changed the cellular morphology, inhibited cell proliferation, and enhanced the expression of P53 (zeige TP53 Antikörper), LC3 (zeige MAP1LC3A Antikörper)-II/I, Beclin-1 (zeige BECN1 Antikörper), AMPK (zeige PRKAA1 Antikörper), and pAMPK while inhibiting the expression of P62 (zeige GTF2H1 Antikörper), Bcl-2, mTOR (zeige FRAP1 Antikörper), and pmTOR in glioma cells.
anti-apoptotic molecules BclxL (zeige BCL2L1 Antikörper) and Bcl-2 and the pro-apoptotic factors BAD and BID (zeige BID Antikörper) cooperate to promote migration of triple-negative breast cancer cells stimulated with cl-CD95L (zeige FASL Antikörper).
CD38, BCL-2, PD-1 (zeige PDCD1 Antikörper), and PD-1L expression in nodal peripheral T-cell lymphoma
high Ki67 (zeige MKI67 Antikörper)/BCL2 index significantly correlated with advanced stage, recurrence, intestinal type, high histologic grade, and lymphatic and perineural invasion in gastric adenocarcinoma
These data strongly suggest that concurrent BCL2 and HDAC (zeige HDAC3 Antikörper) inhibition may offer synergy in the treatment of patients with advanced CTCL (zeige TSPYL2 Antikörper). By using combination therapies and correlating response to gene expression in this way, we hope to achieve more effective and personalized treatments for CTCL (zeige TSPYL2 Antikörper).
In melanoma cells lacking the G-quadruplex-forming sequence in the mRNA of the apoptosis inhibitor Bcl-2, the protein level of Bcl-2 remains virtually unchanged. Consequently, sensitivity to an inducer of apoptosis is not reduced.
This is the first study evaluating the potential relationship between BCL2 and BAX (zeige BAX Antikörper) gene polymorphisms and RRD (zeige DHRS4 Antikörper) in a Greek population, showing a significant association between BAX (zeige BAX Antikörper) rs4645878 polymorphism and RRD (zeige DHRS4 Antikörper) susceptibility. This finding suggests that an apoptotic mechanism is implicated in the pathogenesis of RRD (zeige DHRS4 Antikörper)
Th17 cells are resistant to glucocorticoid-induced apoptosis and cytokine suppression, at least in part due to high levels of BCL-2. These findings support a role of Th17 cells in glucocorticoid-resistant inflammatory conditions such as certain endotypes of asthma.
Acute ethanol exposure induced autophagy-mediated heart toxicity and injury mainly through the ROS (zeige ROS1 Antikörper)-JNK (zeige MAPK8 Antikörper)-Bcl-2 signaling pathway.
E2 protects skeletal myoblasts against apoptosis induced by H2 O2 modulating p53 (zeige TP53 Antikörper) and FoxO (zeige FOXO3 Antikörper) transcription factors and then their target genes Bcl-2, Bim (zeige BCL2L11 Antikörper), Puma (zeige BBC3 Antikörper), PERP (zeige PERP Antikörper), and MDM2 (zeige MDM2 Antikörper), without affecting Noxa (zeige PMAIP1 Antikörper) gene.
Bcl-2 expression has a significant impact on the mineralogical content of enamel crystals of tooth structure
The results suggest that CARP (zeige ANKRD1 Antikörper) can protect against hypoxia-reperfusion induced cardiomyocyte apoptosis, possibly through increasing anti-apoptosis Bcl2 gene expression.
This study provides evidence from transgenic mouse models that Crebbp (zeige CREBBP Antikörper) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.
an essential role for the binding of BCL2 to BIM (zeige BCL2L11 Antikörper) in the survival of noncycling NK cells.
LIGHT signalling pathway combined with IFN-gamma (zeige IFNG Antikörper) induces beta cells apoptosis via an NF-kappaB (zeige NFKB1 Antikörper)/Bcl2-dependent mitochondrial pathway.
Bcl-2 was highly expressed in tubulointerstitial infiltrates in (NZB x NZW)F1 (NZB/NZW) lupus-prone mice.
These results suggest a role for mitochondrial p53 (zeige TP53 Antikörper) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (zeige BAX Antikörper) and Bcl2.
Zebrafish gene expressions of P53 (zeige TP53 Antikörper), Bcl-2, Bax (zeige BAX Antikörper) and caspase-3 (zeige CASP3 Antikörper) were elevated after exposure with microcystin-LR under different ambient temperatures.
Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (zeige S1PR1 Antikörper), and ICAM1 (zeige ICAM1 Antikörper) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.
Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (zeige COX2 Antikörper) and bcl2, but increased p53 (zeige TP53 Antikörper) expression.
Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (zeige NOTCH1 Antikörper) and fish bcl-2, indicating synergy between the Notch (zeige NOTCH1 Antikörper) pathway and the bcl2-mediated antiapoptotic pathway.
Over-expression of STC-1 (zeige STC1 Antikörper) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (zeige CASP3 Antikörper) production in the damaged cells. Findings from this study suggest that STC-1 (zeige STC1 Antikörper) plays a protective role in intestinal cells through an antioxidant mechanism.
BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (zeige BAX Antikörper) expression.
G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.
role of vascular endothelial growth factor receptor-1 (zeige FLT1 Antikörper) in Bcl-2 expression
apoptosis-inducing factor (zeige AIFM1 Antikörper) was expressed in luminal alveolar cells and, in concert with a change in bax (zeige BAX Antikörper) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
mRNA expression of Bax (zeige BAX Antikörper), Bcl-2, caspase-3 (zeige CASP3 Antikörper) and-7 cannot be used as a reliable apoptosis detection method.
These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.
bcl-2 and bax (zeige BAX Antikörper) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (zeige BAX Antikörper)]
excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (zeige CASP3 Antikörper) expression as well as low Bcl-2 expression.
These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (zeige BAX Antikörper) ratio through a mechanism involving protein kinase C (zeige PKC Antikörper).
Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (zeige BAX Antikörper) and decreasing expression of bcl2.
Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (zeige BAX Antikörper).
Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (zeige TP53 Antikörper) and decrease in the antiapoptotic BCl2 proteins.
Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (zeige CASP3 Antikörper).
Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
apoptosis regulator Bcl-2
, protein phosphatase 1, regulatory subunit 50
, B cell lymphoma 2 associated oncogene
, B-cell leukemia/lymphoma 2
, Bcl2-like protein
, BCL2B-cell CLL/lymphoma 2
, B-cell lymphoma protein 2
, B-cell CLL/lymphoma 2
, LOW QUALITY PROTEIN: apoptosis regulator Bcl-2
, Apoptosis regulator Bcl-2