anti-BCL2 (BCL2) Antikörper

Bezeichnung:
anti-B-Cell CLL/lymphoma 2 Antikörper (BCL2)
Auf www.antikoerper-online.de finden Sie aktuell 1098 B-Cell CLL/lymphoma 2 (BCL2) Antikörper von 40 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BCL2 Kits (91) und BCL2 Proteine (28) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1250 BCL2 Produkte verfügbar.
Synonyme:
AW986256, BCL-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, PPP1R50

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Am meisten referenzierte anti-BCL2 Antikörper

  1. Human Polyclonal BCL2 Primary Antibody für IF, IHC (p) - ABIN388095 : Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010 (PubMed)
    Zeige alle 19 Referenzen für 388095

  2. Human Polyclonal BCL2 Primary Antibody für IF (p), IHC (p) - ABIN707156 : Wang, Ma, Su: NF-?B pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. in Biological trace element research 2013 (PubMed)
    Zeige alle 6 Referenzen für 707156

  3. Human Monoclonal BCL2 Primary Antibody für FACS, IHC (fro) - ABIN118990 : Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991 (PubMed)
    Zeige alle 4 Referenzen für 118990

  4. Human Monoclonal BCL2 Primary Antibody für FACS, WB - ABIN1105506 : Gallatin, Weissman, Butcher: A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Zeige alle 2 Referenzen für 1105506

  5. Human Monoclonal BCL2 Primary Antibody für IHC (fro), IF - ABIN1105504 : Ngan, Chen-Levy, Weiss, Warnke, Cleary: Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. in The New England journal of medicine 1988 (PubMed)
    Zeige alle 2 Referenzen für 1105504

  6. Human Monoclonal BCL2 Primary Antibody für FACS - ABIN1105508 : Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: Resistance to Fas-mediated apoptosis in human lung fibroblast. in The European respiratory journal 2002 (PubMed)
    Zeige alle 2 Referenzen für 1105508

  7. Mouse (Murine) Polyclonal BCL2 Primary Antibody für IF (cc), IF (p) - ABIN683428 : Yan, Yuan, Gao, Huang, Ma, Gao, Zhang, Guo, Chen: Overexpression of Human E46K Mutant ?-Synuclein Impairs Macroautophagy via Inactivation of JNK1-Bcl-2 Pathway. in Molecular neurobiology 2014 (PubMed)

  8. Human Polyclonal BCL2 Primary Antibody für WB - ABIN657744 : Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. in Cancer cell 2010 (PubMed)

  9. Human Polyclonal BCL2 Primary Antibody für IHC, WB - ABIN2792106 : Chen, Valencia, Zhong, McColl, Roderick, Bootman, Berridge, Conway, Holmes, Mignery, Velez, Distelhorst: Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. in The Journal of cell biology 2004 (PubMed)

  10. Human Polyclonal BCL2 Primary Antibody für EIA, IHC (p) - ABIN356812 : Liu, Zhou, Li, Sun, Lin, Lang, He, Cao, Yan, Wang, Lu, Han, Cao, Zhang, Zeng: Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. in Cancer research 2008 (PubMed)

Weitere Antikörper gegen BCL2 Interaktionspartner

Mouse (Murine) B-Cell CLL/lymphoma 2 (BCL2) Interaktionspartner

  1. This study provides evidence from transgenic mouse models that Crebbp (zeige CREBBP Antikörper) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.

  2. an essential role for the binding of BCL2 to BIM (zeige BCL2L11 Antikörper) in the survival of noncycling NK cells.

  3. LIGHT signalling pathway combined with IFN-gamma (zeige IFNG Antikörper) induces beta cells apoptosis via an NF-kappaB (zeige NFKB1 Antikörper)/Bcl2-dependent mitochondrial pathway.

  4. Bcl-2 was highly expressed in tubulointerstitial infiltrates in (NZB x NZW)F1 (NZB/NZW) lupus-prone mice.

  5. The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes

  6. the augmentation of endogenous MTA1 (zeige MTA1 Antikörper) expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (zeige ESR1 Antikörper) and BCL2 pathways.

  7. Interestingly, SKPs showed higher protein levels of Bcl-2, Nrf2 (zeige NFE2L2 Antikörper), and HO-1 (zeige HMOX1 Antikörper) than FBs (zeige FBS Antikörper). SKPs exert a beneficial effect on resisting UVB-induced apoptosis, which may be associated with Bcl-2 and Nrf2 (zeige NFE2L2 Antikörper) upregulation.

  8. Bcl-2 is an essential regulator in the survival of doublecortin (zeige DCX Antikörper)-expressing immature neurons.

  9. Results show that the deletion of BCL-2, on its own or in concert with MCL-1 (zeige MCL1 Antikörper), does not affect platelet production or platelet lifespan.

  10. the expression changes observed within the BCL2 family did not depend on STAT3 (zeige STAT3 Antikörper) signalling, in line with its initiating role early in the process, but rather appear to result from relief of repression by STAT5 (zeige STAT5A Antikörper).

Guinea Pig B-Cell CLL/lymphoma 2 (BCL2) Interaktionspartner

  1. bcl-2 and bax (zeige BAX Antikörper) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (zeige BAX Antikörper)]

Human B-Cell CLL/lymphoma 2 (BCL2) Interaktionspartner

  1. MYC (zeige MYC Antikörper) and BCL2 genetic alterations were profiled using next-generation sequencing and high-resolution single nucleotide polymorphism array in 347 de novo diffuse large B-cell lymphoma cases.

  2. findings suggest that expression of cFLIPL regulates the basal interaction of Bcl-2 with Beclin-1 (zeige BECN1 Antikörper) and substantiates p53 (zeige TP53 Antikörper) dependent ubiquitination of Beclin-1 (zeige BECN1 Antikörper) during autophagic stress to determine the fate of cell death or survival.

  3. Our findings suggest that RACK1 (zeige GNB2L1 Antikörper) promotes proliferation and radioresistance in ESCC cells by activating the AKT (zeige AKT1 Antikörper) pathway, upregulating Bcl-2 expression and downregulating protein levels of Bim (zeige BCL2L11 Antikörper). Our study fills in gaps in the field of RACK1 (zeige GNB2L1 Antikörper) and radiation resistance and may provide new possibilities for improving strategies of radiotherapy in esophageal cancer.

  4. Western blot analysis and quantitative real-time polymerase chain reaction demonstrated reduced expression of pri-miR (zeige MLXIP Antikörper)-211, miR (zeige MLXIP Antikörper)-211, TRPM1 (zeige TRPM1 Antikörper), and MLANA (zeige MLANA Antikörper) levels, after Bcl-2 overexpression, associated with increased expression of well-known miR (zeige MLXIP Antikörper)-211 target genes.

  5. this study elucidated mechanisms of BCL2 overexpression and association of this survival pathway with the BCR (zeige BCR Antikörper)/BTK (zeige BTK Antikörper) signaling pathway in MCL (zeige FH Antikörper), and revealed the role of BTK (zeige BTK Antikörper) in noncanonical NF-kappaB (zeige NFKB1 Antikörper) activation, which also promotes cancer cell survival.

  6. Follicular lymphoma with MYC (zeige MYC Antikörper) and BCL2 translocations, so-called double-hit follicular lymphoma (DH-FL), is part of the spectrum of double-hit high-grade lymphoma.

  7. we propose that the existing controversy reflects the diversity of links between Bcl-2 proteins and Ca(2 (zeige CA2 Antikörper)+) signaling, as certainly not all targets or mechanisms will be operative in every cell type and every condition.

  8. Overview of the pleiotropic functions of BCL2 mediated by its physical binding interaction with other proteins and the various ways BCL2 mutations would affect the normal function of the cell leading to the development of diffuse large B-cell lymphomas (review).

  9. Diffuse large B-cell lymphoma with concurrent high MYC (zeige MYC Antikörper) and BCL2 expression shows evidence of active B-cell receptor signaling

  10. Case Reports: BCL2 gene translocations are a recurrent feature of a distinct subset of histiocytic sarcomas that are associated with follicular lymphoma.

Cow (Bovine) B-Cell CLL/lymphoma 2 (BCL2) Interaktionspartner

  1. Over-expression of STC-1 (zeige STC1 Antikörper) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (zeige CASP3 Antikörper) production in the damaged cells. Findings from this study suggest that STC-1 (zeige STC1 Antikörper) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (zeige BAX Antikörper) expression.

  3. G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.

  4. role of vascular endothelial growth factor receptor-1 (zeige FLT1 Antikörper) in Bcl-2 expression

  5. apoptosis-inducing factor (zeige AIFM1 Antikörper) was expressed in luminal alveolar cells and, in concert with a change in bax (zeige BAX Antikörper) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  6. mRNA expression of Bax (zeige BAX Antikörper), Bcl-2, caspase-3 (zeige CASP3 Antikörper) and-7 cannot be used as a reliable apoptosis detection method.

  7. These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.

Rabbit B-Cell CLL/lymphoma 2 (BCL2) Interaktionspartner

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (zeige CASP3 Antikörper) expression as well as low Bcl-2 expression.

  2. These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (zeige BAX Antikörper) ratio through a mechanism involving protein kinase C (zeige PKC Antikörper).

  3. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (zeige BAX Antikörper) and decreasing expression of bcl2.

  4. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (zeige BAX Antikörper).

  5. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (zeige TP53 Antikörper) and decrease in the antiapoptotic BCl2 proteins.

  6. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (zeige CASP3 Antikörper).

  7. Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.

Zebrafish B-Cell CLL/lymphoma 2 (BCL2) Interaktionspartner

  1. These results suggest a role for mitochondrial p53 (zeige TP53 Antikörper) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (zeige BAX Antikörper) and Bcl2.

  2. Zebrafish gene expressions of P53 (zeige TP53 Antikörper), Bcl-2, Bax (zeige BAX Antikörper) and caspase-3 (zeige CASP3 Antikörper) were elevated after exposure with microcystin-LR under different ambient temperatures.

  3. Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (zeige S1PR1 Antikörper), and ICAM1 (zeige ICAM1 Antikörper) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.

  4. Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (zeige COX2 Antikörper) and bcl2, but increased p53 (zeige TP53 Antikörper) expression.

  5. Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (zeige NOTCH1 Antikörper) and fish bcl-2, indicating synergy between the Notch (zeige NOTCH1 Antikörper) pathway and the bcl2-mediated antiapoptotic pathway.

BCL2 Antigen-Profil

Beschreibung des Gens

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Alternative names and synonyms associated with BCL2

  • B-cell CLL/lymphoma 2 (BCL2) Antikörper
  • B-cell CLL/lymphoma 2 (Bcl2) Antikörper
  • B-cell CLL/lymphoma 2 (LOC100224888) Antikörper
  • B cell leukemia/lymphoma 2 (Bcl2) Antikörper
  • B-cell leukemia/lymphoma 2 (bcl2) Antikörper
  • B-cell leukemia/lymphoma 2-like (LOC100359045) Antikörper
  • B-cell CLL/lymphoma 2 protein (BCL-2) Antikörper
  • AW986256 Antikörper
  • BCL-2 Antikörper
  • Bcl2 Antikörper
  • C430015F12Rik Antikörper
  • D630044D05Rik Antikörper
  • D830018M01Rik Antikörper
  • PPP1R50 Antikörper

Bezeichner auf Proteinebene für BCL2

apoptosis regulator Bcl-2 , protein phosphatase 1, regulatory subunit 50 , B cell lymphoma 2 associated oncogene , B-cell leukemia/lymphoma 2 , Bcl2-like protein , PCKBCL2 , BCL2B-cell CLL/lymphoma 2 , B-cell lymphoma protein 2 , Bcl2 , zBlp2 , B-cell CLL/lymphoma 2

GENE ID SPEZIES
596 Homo sapiens
24224 Rattus norvegicus
396282 Gallus gallus
493934 Felis catus
738409 Pan troglodytes
100224888 Taeniopygia guttata
100049703 Sus scrofa
12043 Mus musculus
570772 Danio rerio
403416 Canis lupus familiaris
281020 Bos taurus
100733337 Cavia porcellus
100359045 Oryctolagus cuniculus
100009447 Oryctolagus cuniculus
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