Oncostatin M Receptor Proteine (OSMR)

Bezeichnung:
Oncostatin M Receptor Proteine (OSMR)
Auf www.antikoerper-online.de finden Sie aktuell 20 Oncostatin M Receptor (OSMR) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Oncostatin M Receptor Antikörper (93) und Oncostatin M Receptor Kits (30) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 155 Oncostatin M Receptor Produkte verfügbar.
Synonyme:
OSMRB, PLCA1
alle Proteine anzeigen Gen GeneID UniProt
OSMR 9180 Q99650
OSMR 18414 O70458
OSMR 310132 Q65Z14

Weitere Synonyme anzeigen

Oncostatin M Receptor Proteine (OSMR) nach Spezies

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Am meisten referenzierte Oncostatin M Receptor Proteine

  1. Human Oncostatin M Receptor Protein expressed in Human Cells - ABIN2004128 : Mosley, De Imus, Friend, Boiani, Thoma, Park, Cosman: Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. in The Journal of biological chemistry 1997 (PubMed)
    Zeige alle 2 Referenzen für 2004128

  2. Mouse (Murine) Oncostatin M Receptor Protein expressed in Human Cells - ABIN2007899 : Radtke, Hermanns, Haan, Schmitz-Van De Leur, Gascan, Heinrich, Behrmann: Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 2 Referenzen für 2007899

Weitere Proteine zu Oncostatin M Receptor Interaktionspartnern

Human Oncostatin M Receptor (OSMR) Interaktionspartner

  1. OSM and OSMR are highly expressed in inflammatory bowel disease intestinal mucosa compared to control mucosa. Intestinal stromal cells express abundant OSMR.

  2. OSM:OSMR interactions are able to induce EMT (zeige ITK Proteine), increased cancer stem cell-like properties and enhanced lung colonisation in SCC (zeige CYP11A1 Proteine) cells

  3. the RET (zeige RET Proteine) p.S891A mutation combined with OSMR p.G513D may underlie a novel phenotype manifesting as familial medullary thyroid carcinoma and cutaneous amyloidosis

  4. this study offers new findings on the molecular genetics and disease relevance of mutations in OSMR in Familial primary localized cutaneous amyloidosis.

  5. Oncostatin M (zeige OSM Proteine) and interleukin-31 (zeige IL31 Proteine): Cytokines, receptors, signal transduction and physiology.

  6. primary localized cutaneous amyloidosis has a missense mutation in oncostatin M receptor beta

  7. The interleukin IL-31 (zeige IL31 Proteine)/IL-31receptor axis contributes to tumor growth in human follicular lymphoma.

  8. oncostatin M (zeige OSM Proteine) is a cytokine possessing vigorous antiviral and immunostimulatory properties which is released by APC (zeige APC Proteine) upon interaction with CD40L (zeige CD40LG Proteine) present on activated CD4 (zeige CD4 Proteine)+ T cells.

  9. The disease severity of rheumatoid arthritis and systemic lupus erythematosus can be partially affected by the OSMR promoter polymorphisms.

  10. We conclude that an OSMR/TGM2 (zeige TGM2 Proteine)/integrin-alpha5beta1/fibronectin (zeige FN1 Proteine) pathway is of biological significance in cervical squamous cell carcinoma

Mouse (Murine) Oncostatin M Receptor (OSMR) Interaktionspartner

  1. Osmr expression in healthy mouse colon tissue was detected in endothelial and stromal cells. In agreement with observations of increased OSMR expression in inflamed colon tissue, the number of cells expressing Osmr was markedly increased in the lamina propria of mice with colitis.

  2. Oncostatin M (zeige OSM Proteine) and interleukin-31 (zeige IL31 Proteine): Cytokines, receptors, signal transduction and physiology.

  3. In astrocytes but not microglia, phosphorylation of STAT1 (zeige STAT1 Proteine) and STAT3 (zeige STAT3 Proteine) occurred in response to OSM (zeige OSM Proteine), whereas both microglia and astrocytes responded to hyper-IL-6 (IL-6 (zeige IL6 Proteine) linked to the soluble IL-6 (zeige IL6 Proteine) receptor).

  4. OSM (zeige OSM Proteine) signaling via OSMR in synovial fibroblasts has the potential to contribute significantly to joint destruction in inflammatory arthritis.

  5. defects in OSM (zeige OSM Proteine) signaling promote the deterioration of high-fat diet-induced obesity and related metabolic disorders

  6. Data indicate that OSM (zeige OSM Proteine) receptor beta subunit (zeige POLG Proteine)-deficient (OSMRbeta(-/-)) mice exhibited phenotypic changes in adipose tissue macrophages (ATMs) to M1, increased proinflammatory cytokines in the adipose tissue, and systemic insulin (zeige INS Proteine) resistance.

  7. These data indicate that the transient RANKL (zeige TNFSF11 Proteine) induction by intermittent PTH (zeige PTH Proteine) administration, which is associated with its anabolic action, is changed to a prolonged induction in OSMR-deficient osteoblasts, resulting in bone destruction.

  8. Bone formation can be stimulated independently of bone resorption and provide new insights into OSMR signaling.

  9. Expression of oncostatin M receptor beta in a specific subset of nociceptive sensory neurons.

  10. Mice deficient in OSM (zeige OSM Proteine) receptor showed impaired liver regeneration with persistent parenchymal necrosis after carbon tetrachloride exposure. Recovery of liver mass from partial hepatectomy was also significantly delayed in OSMR(-/-) mice.

Oncostatin M Receptor (OSMR) Protein Überblick

Protein Überblick

This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Oncostatin M Receptor (OSMR)

  • oncostatin M receptor (OSMR)
  • oncostatin M receptor (Osmr)
  • OSMRB Protein
  • PLCA1 Protein

Bezeichner auf Proteinebene für Oncostatin M Receptor Proteine (OSMR)

IL-31 receptor subunit beta , IL-31R subunit beta , IL-31R-beta , IL-31RB , interleukin-31 receptor subunit beta , oncostatin-M specific receptor beta subunit , oncostatin-M-specific receptor subunit beta , oncostatin receptor , oncostatin-M specific receptor subunit beta , oncostatin M specific receptor

GENE ID SPEZIES
9180 Homo sapiens
489223 Canis lupus familiaris
18414 Mus musculus
310132 Rattus norvegicus
100356631 Oryctolagus cuniculus
100716168 Cavia porcellus
100519929 Sus scrofa
514720 Bos taurus
427446 Gallus gallus
101105948 Ovis aries
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