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anti-PTEN (PTEN) Antikörper

anti-Phosphatase and Tensin Homolog Antikörper (PTEN)
Auf finden Sie aktuell 0 Phosphatase and Tensin Homolog (PTEN) Antikörper von unterschiedlichen Herstellern. Insgesamt sind aktuell 0 PTEN Produkte verfügbar.
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus PTEN PTEN 19211 O08586
Anti-Ratte PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

Weitere Synonyme anzeigen

Weitere Antikörper gegen PTEN Interaktionspartner

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. PTEN mediates hepatic macrophage activation in liver fibrosis.

  2. miR (zeige MLXIP Antikörper)-718 modulates PI3K/Akt (zeige AKT1 Antikörper) signaling by directly down-regulating phosphatase and tensin homolog (PTEN), thereby promoting phosphorylation of Akt (zeige AKT1 Antikörper), which leads to a decrease in proinflammatory cytokine production.

  3. Downregulated miR (zeige MLXIP Antikörper)-152 induced impaired hepatic glycogenesis by targeting PTEN. PTEN participated in miR (zeige MLXIP Antikörper)-152-mediated glycogenesis in hepatocytes via regulation of the AKT (zeige AKT1 Antikörper)/GSK pathway

  4. The findings of this study suggest that deletion of Pten in the brain results in impaired bone mass and mineralization, which may contribute to weaker bones and thereby a higher fracture risk.

  5. phenotypic and genetic changes within the pre-neoplastic mammary epithelium of mice with and without stromal PTEN expression

  6. Data suggest that expression, processing, and activation of (that is, signal transduction via) Notch1 (neurogenic locus notch homolog protein 1 (zeige NOTCH1 Antikörper)), Pten (phosphatase and tensin homolog), and Akt1 (thymoma viral proto-oncogene 1) are involved in oogenesis; oogenesis proceeds via both recruitment of primordial follicles and proliferation of granulosa cells.

  7. this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK (zeige PBK Antikörper)/PTEN/Akt (zeige AKT1 Antikörper) signaling pathway

  8. miR (zeige MLXIP Antikörper)-21 overexpression contributes to liver regeneration and hepatocyte proliferation by targeting PTEN

  9. Liver-specific deletion of PTEN significantly ameliorates chronic ethanol-induced increases in hepatocellular damage.

  10. Immunofluorescence studies revealed the abnormal sprouting of mossy fibers in the DG of the Pten-cKO mice prior to the onset of seizures.

Human Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. This study indicates that miR (zeige MLXIP Antikörper)-543 promotes proliferation and invasion of NSCLC cell lines by PTEN. The miR (zeige MLXIP Antikörper)-543 may represent a potential therapeutic target for gefitinib-resistant NSCLC intervention.

  2. the present study was designed to explore whether PTEN was involved in APN (zeige ANPEP Antikörper)-induced osteogenic differentiation of human bone marrow mesenchymal stem cells, and the related mechanisms.

  3. Findings suggest that PTEN and DNMT3B possess common regulation features as well as certain ethnic differences in expression between Han women and Uygur women.

  4. pregulation of PTEN and LKB1 (zeige STK11 Antikörper) in concert with negative or low levels of activated Akt (zeige AKT1 Antikörper), mTOR (zeige FRAP1 Antikörper) and S6 indicates that PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) pathway may not play a significant role in pathogenesis of leiomyoma.

  5. miR (zeige MLXIP Antikörper)-29a may regulate the radiosensitivity of intestinal cell lines by targeting the PTEN gene

  6. FER1L4 not only showed downregulation in endometrial carcinoma tissues and cells, but also regulated PTEN expression and Akt (zeige AKT1 Antikörper) signaling, which might contribute to its inhibition on cell proliferation.

  7. CD164 (zeige CD164 Antikörper) expression may have affected the proliferation and apoptosis of human glioma cells via the PTEN/phosphoinositide 3-kinase/AKT (zeige AKT1 Antikörper) pathway.

  8. our study reveals a novel mechanism of crosstalk amongst SDHD (zeige SDHD Antikörper), PTEN and autophagy pathways and their potential roles in thyroid carcinogenesis

  9. partial knockdown of Pten rescues the toxicity observed in the NSC34 (G4C2)102 cellular gain-of-toxic function model of C9ORF72 (zeige C9ORF72 Antikörper)-ALS (zeige IGFALS Antikörper). Our data indicate that PTEN may provide a potential therapeutic target to ameliorate toxic effects of the (G4C2)n repeat.

  10. TUG1 could serve as a miR (zeige MLXIP Antikörper)-26a sponge in human glioma cells, contributing to the upregulation of PTEN. This study revealed a new TUG1/miR (zeige MLXIP Antikörper)-26a/PTEN regulatory mechanism and provided a further understanding of the tumor-suppressive role of TUG1 in glioma development.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. PTEN, FOXO3A (zeige FOXO3 Antikörper) and PKB (zeige AKT1 Antikörper) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. the miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 (zeige BMPR2 Antikörper) genes.

  2. miR (zeige MYLIP Antikörper)-26b participates in the inflammatory response of LPS (zeige IRF6 Antikörper)-stimulated bAMs by modulating the NF-kappaB (zeige NFKB1 Antikörper) pathway through targeting PTEN.

  3. Pten expression levels in the mammary glands of dairy cows, was investigated.

  4. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (zeige NOS3 Antikörper) activation in vascular endothelial cells.

  5. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  6. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (zeige DVL2 Antikörper).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen-Profil

Beschreibung des Gens

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) Antikörper
  • phosphatase and tensin homolog (PTEN) Antikörper
  • phosphatase and tensin homolog (pten) Antikörper
  • 10q23del Antikörper
  • 2310035O07Rik Antikörper
  • A130070J02Rik Antikörper
  • AI463227 Antikörper
  • B430203M17Rik Antikörper
  • BZS Antikörper
  • CWS1 Antikörper
  • DEC Antikörper
  • GLM2 Antikörper
  • MHAM Antikörper
  • Mmac Antikörper
  • MMAC1 Antikörper
  • PTEN1 Antikörper
  • PTENP1 Antikörper
  • TEP1 Antikörper

Bezeichner auf Proteinebene für PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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