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anti-PTEN (PTEN) Antikörper

anti-Phosphatase and Tensin Homolog Antikörper (PTEN)
Auf finden Sie aktuell 0 Phosphatase and Tensin Homolog (PTEN) Antikörper von unterschiedlichen Herstellern. Insgesamt sind aktuell 0 PTEN Produkte verfügbar.
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus PTEN PTEN 19211 O08586
Anti-Ratte PTEN PTEN 50557  
Anti-Human PTEN PTEN 5728 P60484

Weitere Synonyme anzeigen

Weitere Antikörper gegen PTEN Interaktionspartner

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. Inhibition of PLK1 (zeige PLK1 Antikörper) activity or overexpression of a non-phosphorylatable PLK1 (zeige PLK1 Antikörper) mutant reduces the polyploid cell population.

  2. These findings demonstrate an important role for Pten in maintenance of airway epithelial phenotype integrity.

  3. Data indicate that hydrogen sulfide (zeige SQRDL Antikörper) H(2)S inhibits Abeta (zeige APP Antikörper)-induced neuronal apoptosis by attenuating mitochondrial translocation of phosphatase and tensin (zeige TNS1 Antikörper) homologs deleted on chromosome 10 and that activation of PI3K/AKT (zeige AKT1 Antikörper) signaling pathway plays a critical role in H(2)S-mediated neuronal protection. Our findings provide a novel route into the molecular mechanisms of neuronal apoptosis in Alzheimer's disease.

  4. miR (zeige MLXIP Antikörper)-217inhibition can protectively antagonize high glucose-induced podocyte damage and insulin (zeige INS Antikörper) resistance by restoring the defective autophagy pathway via targeting PTEN

  5. that Pten, through the Dlg1 (zeige DLG1 Antikörper)-binding ability of its PDZ (zeige INADL Antikörper)-binding domain , accumulates phosphorylated Eg5 (zeige KIF11 Antikörper) at duplicated centrosomes to establish symmetrical bipolar spindles that properly segregate chromosomes

  6. PTEN mediates hepatic macrophage activation in liver fibrosis.

  7. miR (zeige MLXIP Antikörper)-718 modulates PI3K/Akt (zeige AKT1 Antikörper) signaling by directly down-regulating phosphatase and tensin homolog (PTEN), thereby promoting phosphorylation of Akt (zeige AKT1 Antikörper), which leads to a decrease in proinflammatory cytokine production.

  8. Downregulated miR (zeige MLXIP Antikörper)-152 induced impaired hepatic glycogenesis by targeting PTEN. PTEN participated in miR (zeige MLXIP Antikörper)-152-mediated glycogenesis in hepatocytes via regulation of the AKT (zeige AKT1 Antikörper)/GSK pathway

  9. The findings of this study suggest that deletion of Pten in the brain results in impaired bone mass and mineralization, which may contribute to weaker bones and thereby a higher fracture risk.

  10. phenotypic and genetic changes within the pre-neoplastic mammary epithelium of mice with and without stromal PTEN expression

Human Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. The miR (zeige MLXIP Antikörper)-19b-PTEN signaling pathway may serve as a novel therapeutic target in the context of ventilator-associated lung fibrosis.

  2. Results show that MiR (zeige MLXIP Antikörper)-20b binds to the 3'-UTR (zeige UTS2R Antikörper) of PTEN and their expression inversely correlates in esophageal cancer and cells.

  3. We show that the decrease in PI(4,5)P2 level under non-stimulated conditions inhibits PTEN activity leading to the aberrant activation of the oncoprotein Akt (zeige AKT1 Antikörper). As well as defining a novel mechanism of Akt (zeige AKT1 Antikörper) phosphorylation with important therapeutic consequences, we also demonstrate that differential expression levels of FGFR2 (zeige FGFR2 Antikörper), Plc11 and Grb2 (zeige GRB2 Antikörper) correlate with patient survival

  4. Inhibition of PLK1 (zeige PLK1 Antikörper) activity or overexpression of a non-phosphorylatable PLK1 (zeige PLK1 Antikörper) mutant reduces the polyploid cell population.

  5. In perspective of the crucial role PTEN plays in balancing proliferation and apoptosis, we propose PTEN as a valuable marker in the diagnosis, assessment of tumor grade, and disease stage in hepatocellular carcinoma patients

  6. PTEN nuclear expression increased with increasing mitotic rate in gastrointestinal stromal tumors.

  7. our findings demonstrated that dysregulation of miR (zeige MLXIP Antikörper)-19a plays critical roles in the osteosarcoma stem cells, at least in part via targeting the phosphatase and tensin homolog (PTEN) deleted on chromosome 10. Knockdown of miR (zeige MLXIP Antikörper)-19a may represent a potential strategy for the osteosarcoma treatment.

  8. our data suggest that microRNA-200c plays an oncogenic role in nasopharyngeal carcinoma by targeting PTEN

  9. Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer have been presented.

  10. we demonstrate that HOTAIR downregulates miR (zeige MLXIP Antikörper)-29b expression and attenuates its control on epigenetic regulation, leading to enhanced PTEN methylation, which contributes to the progression of liver fibrosis.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. PTEN, FOXO3A (zeige FOXO3 Antikörper) and PKB (zeige AKT1 Antikörper) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. the miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 (zeige BMPR2 Antikörper) genes.

  2. miR (zeige MYLIP Antikörper)-26b participates in the inflammatory response of LPS (zeige IRF6 Antikörper)-stimulated bAMs by modulating the NF-kappaB (zeige NFKB1 Antikörper) pathway through targeting PTEN.

  3. Pten expression levels in the mammary glands of dairy cows, was investigated.

  4. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (zeige NOS3 Antikörper) activation in vascular endothelial cells.

  5. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  6. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) Interaktionspartner

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (zeige DVL2 Antikörper).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN Antigen-Profil

Beschreibung des Gens

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) Antikörper
  • phosphatase and tensin homolog (PTEN) Antikörper
  • phosphatase and tensin homolog (pten) Antikörper
  • 10q23del Antikörper
  • 2310035O07Rik Antikörper
  • A130070J02Rik Antikörper
  • AI463227 Antikörper
  • B430203M17Rik Antikörper
  • BZS Antikörper
  • CWS1 Antikörper
  • DEC Antikörper
  • GLM2 Antikörper
  • MHAM Antikörper
  • Mmac Antikörper
  • MMAC1 Antikörper
  • PTEN1 Antikörper
  • PTENP1 Antikörper
  • TEP1 Antikörper

Bezeichner auf Proteinebene für PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
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