anti-MGMT (MGMT) Antikörper

Bezeichnung:
anti-O6-Methylguanine-DNA-Methyltransferase Antikörper (MGMT)
Auf www.antikoerper-online.de finden Sie aktuell 205 O6-Methylguanine-DNA-Methyltransferase (MGMT) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MGMT Kits (29) und MGMT Proteine (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 271 MGMT Produkte verfügbar.
Synonyme:
Agat, AGT, AI267024

Meistgesuchte Reaktivitäten zu anti-MGMT (MGMT) Antikörper

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anti-Human MGMT Antikörper:

anti-Mouse (Murine) MGMT Antikörper:

anti-Rat (Rattus) MGMT Antikörper:

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Am meisten referenzierte anti-MGMT Antikörper

  1. Human Monoclonal MGMT Primary Antibody für CyTOF, FACS - ABIN151202 : Kokkinakis, Ahmed, Delgado, Fruitwala, Mohiuddin, Albores-Saavedra: Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents. in Cancer research 1998 (PubMed)
    Zeige alle 19 Referenzen für 151202

  2. Human Monoclonal MGMT Primary Antibody für WB - ABIN1882266 : Tano, Shiota, Collier, Foote, Mitra: Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Zeige alle 5 Referenzen für 1882266

  3. Human Monoclonal MGMT Primary Antibody für WB - ABIN1882265 : Rydberg, Spurr, Karran: cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cells. in The Journal of biological chemistry 1990 (PubMed)
    Zeige alle 5 Referenzen für 1882265

  4. Human Monoclonal MGMT Primary Antibody für IHC (p), IHC - ABIN152115 : Takeshita, Inoshita, Taguchi, Okuda, Fukuhara, Oyama, Ohashi, Sano, Takeuchi, Yamada: High incidence of low O(6)-methylguanine DNA methyltransferase expression in invasive macroadenomas of Cushing's disease. in European journal of endocrinology 2009 (PubMed)
    Zeige alle 5 Referenzen für 152115

  5. Human Monoclonal MGMT Primary Antibody für FACS, IHC (p) - ABIN180357 : Harris, Potter, Remack, Brent: A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells. in Cancer research 1992 (PubMed)
    Zeige alle 4 Referenzen für 180357

  6. Human Polyclonal MGMT Primary Antibody für FACS, IHC (p) - ABIN391514 : Kim, Suh, Choi, Kang, Shin, Lee, Moon, Kim: Inactivation of O6-methylguanine-DNA methyltransferase in soft tissue sarcomas: association with K-ras mutations. in Human pathology 2009 (PubMed)
    Zeige alle 3 Referenzen für 391514

  7. Human Polyclonal MGMT Primary Antibody für IF (p), IHC (p) - ABIN730768 : Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive. in Journal of Alzheimer's disease : JAD 2014 (PubMed)

Weitere Antikörper gegen MGMT Interaktionspartner

Human O6-Methylguanine-DNA-Methyltransferase (MGMT) Interaktionspartner

  1. MGMT protein expression assessed by immunohistochemistry did not play an important role as a predictive marker for alkylating agents.

  2. Glioblastoma patients with high IFIT1 (zeige IFIT1 Antikörper) and low MGMT expression have an improved prognosis.

  3. Glioblastoma patients with high expression of hepatocyte growth factor (zeige HGF Antikörper) or unmethylated O(6)-methylguanine-DNA methyltransferase may benefit from onartuzumab plus bevacizumab chemotherapy.

  4. results demonstrate MGMT methylation is a reliable and independent prognostic factor in DAs (zeige ube3a Antikörper). Methylation of MGMT is associated with poor prognosis in patients with stage III DAs (zeige ube3a Antikörper)

  5. investigation of MGMT promoter methylation and in particular BRAF (zeige BRAF Antikörper) V600E mutations represent reliable additional tools to sustain differentiation of Giant Cell Glioblastoma (gcGBM) from Pleomorphic Xanthoastrocytoma (PXA) on a molecular basis. Based on these data specific BRAF (zeige BRAF Antikörper) kinase inhibitors could represent a promising agent in the therapy of PXA and their use should be emphasized.

  6. Efficacy of TMZ in adrenocortical carcinoma cells does not seem to be limited by low methylation of MGMT.

  7. MGMT is involved in gastric carcinogenesis via downregulation of MMP2 (zeige MMP2 Antikörper).

  8. Study suggests that treatment effects of upfront radiotherapy plus concomitant and maintenance temozolomide might offset some of the beneficial effects of cytoreductive surgery in case of a methylated MGMT promoter whereas this unfortunately seems not be true for unmethylated tumors

  9. our results suggest that an aberrant messenger RNA expression may be the outcome of CpG, CHG, and CHH methylation in O(6)-methylguanine-DNA methyltransferase, whereas outcome of CHG and CHH methylation in runt-related transcription factor 3 promoters along with risk factors such as consumption of tobacco, betel nut, and smoking habits in esophageal cancer from Northeast India

  10. Loss of O-6-methylguanine-DNA methyltransferase protein was very frequent in the incidence of esophageal cancer from North Indian patients, and methylation of the promoter region of O-6-methylguanine-DNA methyltransferase was significantly associated in its downregulation

Mouse (Murine) O6-Methylguanine-DNA-Methyltransferase (MGMT) Interaktionspartner

  1. Snell, GHKRO, and PAPPA (zeige PAPPA Antikörper)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT) and N-myc downstream-regulated gene 1 (NDRG1 (zeige NDRG1 Antikörper)).

  2. This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT, but not AAG (zeige C16orf35 Antikörper), as a key node in determining a carcinogenic threshold.

  3. Findings suggest that O6-methylguanine-DNA methyltransferase (MGMT)-mediated temozolomide resistance is associated with increased histone acetylation.

  4. Loss of MGMT expression and high Ezrin (zeige EZR Antikörper) protein expression leads to esophageal cancer.

  5. Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.

  6. ta indicate that Zik1 and Gja9 (zeige GJD2 Antikörper) demonstrated cancer-specific aberrant DNA methylation (zeige HELLS Antikörper), whereas, Cdkn2a/p16 (zeige CDKN2A Antikörper), Igfbp3 (zeige IGFBP3 Antikörper), Mgmt, Id4 (zeige ID4 Antikörper), and Cxcr4 (zeige CXCR4 Antikörper) were methylated in both the AOM (zeige COL2A1 Antikörper) tumors and normal colon mucosa.

  7. Roles of MGMT and MLH1 (zeige MLH1 Antikörper) proteins in alkylation-induced apoptosis and mutagenesis.

  8. Repression of MGMT is associated with precancerous conditions in hyperplastic mucosa adjacent to colon cancer

  9. GAMT (zeige GAMT Antikörper) and AGAT (zeige GATM Antikörper) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (zeige DMD Antikörper) muscle compared to C57

  10. MGMT-deficient cells would likely exhibit an increased mutational burden, but only following exposures to specific environmental mutagens such as the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

MGMT Antigen-Profil

Beschreibung des Gens

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a

Alternative names and synonyms associated with MGMT

  • O-6-methylguanine-DNA methyltransferase (MGMT) Antikörper
  • O-6-methylguanine-DNA methyltransferase (Mgmt) Antikörper
  • Agat Antikörper
  • AGT Antikörper
  • AI267024 Antikörper

Bezeichner auf Proteinebene für MGMT

6-O-methylguanine-DNA methyltransferase , O-6-methylguanine-DNA-alkyltransferase , O6-methylguanine-DNA methyltransferase , methylated-DNA--protein-cysteine methyltransferase , methylguanine-DNA methyltransferase , O-6-alkylguanine-DNA alkyltransferase , 0-6-methylguanine-DNA methyltransferase , O(6)-alkylguanine-DNA alkyltransferase , O6-alkylguanine-DNA alkyltransferase , O6-methylguanine-DNA methyltranferase , O6-alkylguanine-DNA-alkyltransferase , O6-methylguanine-DNA-methyltransferase

GENE ID SPEZIES
4255 Homo sapiens
17314 Mus musculus
25332 Rattus norvegicus
100733185 Cavia porcellus
100155050 Sus scrofa
616091 Bos taurus
442978 Canis lupus familiaris
423965 Gallus gallus
101106897 Ovis aries
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