anti-FADD (FADD) Antikörper

Bezeichnung:
anti-Fas (TNFRSF6)-Associated Via Death Domain Antikörper (FADD)
Auf www.antikoerper-online.de finden Sie aktuell 274 Fas (TNFRSF6)-Associated Via Death Domain (FADD) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FADD Kits (13) und FADD Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 325 FADD Produkte verfügbar.
Synonyme:
Mort1, Mort1/FADD, TNFRSF6

Meistgesuchte Reaktivitäten zu anti-FADD (FADD) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human FADD Antikörper:

anti-Mouse (Murine) FADD Antikörper:

anti-Rat (Rattus) FADD Antikörper:

Alle verfügbaren anti-FADD Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-FADD Antikörper

  1. Human Monoclonal FADD Primary Antibody für WB - ABIN395764 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Zeige alle 5 Referenzen für 395764

  2. Human Monoclonal FADD Primary Antibody für IF, IP - ABIN967944 : Chang, Xing, Pan, Algeciras-Schimnich, Barnhart, Yaish-Ohad, Peter, Yang: c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. in The EMBO journal 2002 (PubMed)
    Zeige alle 5 Referenzen für 967944

  3. Human Polyclonal FADD Primary Antibody für EIA, IHC (p) - ABIN358126 : Hsu, Shu, Pan, Goeddel: TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. in Cell 1996 (PubMed)
    Zeige alle 3 Referenzen für 358126

  4. Human Monoclonal FADD Primary Antibody für EIA, IHC (p) - ABIN317514 : Bannerman, Tupper, Kelly, Winn, Harlan: The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta. in The Journal of clinical investigation 2002 (PubMed)
    Zeige alle 3 Referenzen für 317514

  5. Human Polyclonal FADD Primary Antibody für IP, WB - ABIN222894 : Chen, Texada, Duggan, Liang, Reden, Kooragayala, Langford: Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 3 Referenzen für 222894

  6. Mouse (Murine) Polyclonal FADD Primary Antibody für WB - ABIN389559 : Zhang, Winoto: A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis. in Molecular and cellular biology 1996 (PubMed)
    Zeige alle 2 Referenzen für 389559

  7. Human Polyclonal FADD Primary Antibody für IHC (p), WB - ABIN669471 : Soni, Adebiyi: Early septic insult in neonatal pigs increases serum and urinary soluble Fas ligand and decreases kidney function without inducing significant renal apoptosis. in Renal failure 2016 (PubMed)

  8. Human Polyclonal FADD Primary Antibody für IF, IHC - ABIN1534444 : Chinnaiyan, ORourke, Tewari, Dixit: FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. in Cell 1995 (PubMed)

  9. Human Polyclonal FADD Primary Antibody für IHC, WB - ABIN2792110 : Thomas, Henson, Reed, Salsbury, Thorburn: Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen FADD Interaktionspartner

Human Fas (TNFRSF6)-Associated Via Death Domain (FADD) Interaktionspartner

  1. Caspase-8 can serve in two distinct roles in response to TRAIL receptor engagement, as a scaffold for assembly of a Caspase-8-FADD-RIPK1 "FADDosome" complex, leading to NFkappaB-dependent inflammation, or as a protease that promotes apoptosis.

  2. Using the tDED filament structure as a template, structural analyses reveal the interaction surfaces between FADD and caspase-8 (zeige CASP8 Antikörper) and the distinct mechanisms of regulation by cFLIP (zeige CFLAR Antikörper) and MC159 through comingling and capping, respectively.

  3. This study reveals an essential role of SUMOylated FADD in Drp1 (zeige CRMP1 Antikörper)- and caspase-10 (zeige CASP10 Antikörper)-dependent necrosis.

  4. In myelodysplastic syndrome, FADD expression is regulated by SPAG6 (zeige SPAG6 Antikörper) which influences its interaction with TRAIL death receptors.

  5. High levels of FADD and caspase-8 (zeige CASP8 Antikörper), but not caspase-3 (zeige CASP3 Antikörper), were associated with increased incidence of coronary events in subjects from the general population.

  6. Both Fas associated via death domain gene copy number amplification and high protein expression were significantly associated with lymph node metastasis and had the shortest disease-free survival and overall survival.

  7. FADD, as well as NEMO (zeige IKBKG Antikörper), is a substrate for LUBAC ubiquitin ligase (E3) complex, composed of the HOIP (zeige RNF31 Antikörper), HOIL-1L (zeige RBCK1 Antikörper), and SHARPIN (zeige SHARPIN Antikörper) subunits.

  8. autoinflammation-associated H443P nlrc4 (zeige NLRC4 Antikörper) mutant is altered in interaction with SUG1 (zeige PSMC5 Antikörper) and ubiquitinated proteins, triggering constitutive caspase-8 (zeige CASP8 Antikörper)-mediated cell death dependent on FADD but independent of Ser (zeige SIGLEC1 Antikörper)(533) phosphorylation.

  9. this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of FADD

  10. Authors identify non-canonical nuclear factor-kappaB (NF-kappaB (zeige NFKB1 Antikörper)) signaling up regulated and it was directly linked with the tumor necrosis with MT2A (zeige MT2 Antikörper) and pFADD genes. pFADD with MT2A (zeige MT2 Antikörper) can inhibit the apoptosis and promote proliferation, of colorectal cancer cells.

Mouse (Murine) Fas (TNFRSF6)-Associated Via Death Domain (FADD) Interaktionspartner

  1. The authors conclude that FADD is a master regulator of glucose and fat metabolism.

  2. Mice deficient in RIPK3 (zeige RIPK3 Antikörper) or doubly deficient in MLKL and FADD, but not MLKL alone, are more susceptible to influenza A virus than their wild-type counterparts, revealing an important role for RIPK3 (zeige RIPK3 Antikörper)-mediated apoptosis in antiviral immunity.

  3. Wild-type cells can execute apoptosis via both, the mitochondrial and the receptor-mediated pathway whereas FADD-deficient cells can only activate the intrinsic pathway. There is a difference in UVC radiation response between two cell lines indicating the role of FADD in the selection of cell death modality.

  4. This study reveals an essential role of SUMOylated FADD in Drp1 (zeige CRMP1 Antikörper)- and caspase-10 (zeige CASP10 Antikörper)-dependent necrosis.

  5. knockdown of cFLIPL and induced expression of FADD rapidly accumulate intracellular ROS (zeige ROS1 Antikörper) accompanied by JNK1 (zeige MAPK8 Antikörper) activation to substantiate apoptosis.

  6. A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.

  7. Deletion of FADD in macrophages and granulocytes results in RIP3 (zeige MPRIP Antikörper)- and MyD88 (zeige MYD88 Antikörper)-dependent systemic inflammation.

  8. A constitutively phosphoryl-mimicking mutation of Fas (zeige FAS Antikörper)-associated death domain (FADD-D) enhances Notch-1 (zeige NOTCH1 Antikörper) signaling and compromises Wnt (zeige WNT2 Antikörper) signaling in both cultured myoblasts and regenerating muscles.

  9. Beta amyloid-induced upregulation of death receptor 6 (zeige TNFRSF21 Antikörper) accelerates the toxic effect of N-terminal fragment of amyloid precursor protein (zeige APP Antikörper)

  10. Phosphorylation of FADD by the kinase CK1alpha (zeige CSNK1A1 Antikörper) promotes KRASG12D-induced lung cancer.

Pig (Porcine) Fas (TNFRSF6)-Associated Via Death Domain (FADD) Interaktionspartner

  1. FADD induces apoptosis

Cow (Bovine) Fas (TNFRSF6)-Associated Via Death Domain (FADD) Interaktionspartner

  1. mapping and sequencing of bovine FADD cDNA, and characterization of its expression in endothelial cells

FADD Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

Alternative names and synonyms associated with FADD

  • Fas (TNFRSF6)-associated via death domain (FADD) Antikörper
  • Fas (TNFRSF6)-associated via death domain (Fadd) Antikörper
  • Mort1 Antikörper
  • Mort1/FADD Antikörper
  • TNFRSF6 Antikörper

Bezeichner auf Proteinebene für FADD

Fas-associating death domain-containing protein , Fas-associating protein with death domain , growth-inhibiting gene 3 protein , mediator of receptor induced toxicity , mediator of receptor-induced toxicity , protein FADD , FAS-associated death domain protein , FAS-associating death domain-containing protein , Fas (TNF receptor superfamily, member 6) , Fas-associated via death domain

GENE ID SPEZIES
8772 Homo sapiens
14082 Mus musculus
266610 Rattus norvegicus
595129 Sus scrofa
493720 Bos taurus
611694 Canis lupus familiaris
Ausgewählte Anbieter für anti-FADD (FADD) Antikörper
Haben Sie etwas anderes gesucht?