anti-Caspase 6 (CASP6) Antikörper

anti-Caspase 6, Apoptosis-Related Cysteine Peptidase Antikörper (CASP6)
Auf finden Sie aktuell 316 Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Caspase 6 Kits (35) und Caspase 6 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 387 Caspase 6 Produkte verfügbar.
casp6, caspase-6, mCASP-6, MCH2, xCaspase-6, zgc:112960
Alle Antikörper anzeigen Gen GeneID UniProt
CASP6 12368 O08738
CASP6 83584  
CASP6 839 P55212

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Caspase 6 (CASP6) Antikörper

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anti-Mouse (Murine) Caspase 6 Antikörper:

anti-Rat (Rattus) Caspase 6 Antikörper:

anti-Human Caspase 6 Antikörper:

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Am meisten referenzierte anti-Caspase 6 Antikörper

  1. Human Monoclonal Caspase 6 Primary Antibody für WB - ABIN967553 : Cohen: Caspases: the executioners of apoptosis. in The Biochemical journal 1997 (PubMed)
    Zeige alle 5 Referenzen für 967553

  2. Human Polyclonal Caspase 6 Primary Antibody für EIA, IHC (p) - ABIN358091 : Kalinin, Kalinin, Aho, Uitto, Aho: Breaking the connection: caspase 6 disconnects intermediate filament-binding domain of periplakin from its actin-binding N-terminal region. in The Journal of investigative dermatology 2005 (PubMed)
    Zeige alle 5 Referenzen für 358091

  3. Human Monoclonal Caspase 6 Primary Antibody für WB - ABIN264405 : Orth, Chinnaiyan, Garg, Froelich, Dixit: The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A. in The Journal of biological chemistry 1996 (PubMed)
    Zeige alle 4 Referenzen für 264405

  4. Human Polyclonal Caspase 6 Primary Antibody für IHC (p), WB - ABIN388106 : MacLachlan, El-Deiry: Apoptotic threshold is lowered by p53 transactivation of caspase-6. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Zeige alle 3 Referenzen für 388106

  5. Human Polyclonal Caspase 6 Primary Antibody für IHC (p), WB - ABIN657756 : Würstle, Laussmann, Rehm: The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 657756

  6. Human Polyclonal Caspase 6 Primary Antibody für IHC, WB - ABIN223017 : Nikolaev, McLaughlin, OLeary, Tessier-Lavigne: APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. in Nature 2009 (PubMed)
    Zeige alle 2 Referenzen für 223017

  7. Human Polyclonal Caspase 6 Primary Antibody für IHC (p), WB - ABIN389525 : Horowitz, Patterson, Guillozet-Bongaarts, Reynolds, Carroll, Weintraub, Bennett, Cryns, Berry, Binder: Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)

  8. Human Polyclonal Caspase 6 Primary Antibody für IHC, ELISA - ABIN1536082 : Yashiro, Qiu, Hasegawa, Zhang, Matsuzaki, Hirakawa: An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells. in British journal of cancer 2011 (PubMed)

Weitere Antikörper gegen Caspase 6 Interaktionspartner

Mouse (Murine) Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Interaktionspartner

  1. caspase-6 could regulate breast cancer cell invasion by modulating MMP-2 (zeige MMP2 Antikörper) and MMP-9 (zeige MMP9 Antikörper) expression in 4T1 tumor-associated macrophages

  2. Casp6 is unlikely to be involved in colitis-associated tumors.

  3. p53 (zeige TP53 Antikörper) activity is an important upstream regulator of caspase-6 activity in muscle tissue.

  4. TNFalpha (zeige TNF Antikörper)-induced RIP1 (zeige RALBP1 Antikörper)-independent caspase-6 activation was involved in regulating the relationship between autophagy and necroptosis.

  5. CASP6 released from axonal terminals regulates microglial TNF-alpha (zeige TNF Antikörper) secretion, synaptic plasticity, and inflammatory pain.

  6. both Caspase-3 (zeige CASP3 Antikörper) and Caspase-6 are implicated in axon degeneration that occurs as a part of normal development.

  7. Casp6-/- neurons are protected against excitotoxicity, nerve growth factor deprivation and myelin-induced axonal degeneration. Furthermore, Casp6-deficient mice show an age-dependent increase in cortical and striatal volume.

  8. This study demonistrated that elimination of caspase-6 protein and activity in the BACHD mouse model does not prevent the production of a 586 aa Htt (zeige HTT Antikörper) proteolytic fragment in the brain.

  9. Neutrophil/macrophage contact activates CASP-6, producing interleukin-1 receptor-associated kinase-M (zeige IRAK3 Antikörper) (IRAK-M (zeige IRAK3 Antikörper)) cleavage and de-repression of alveolar macrophages; CASP-6 deletion protects mice from death caused by bacterial peritonitis.

  10. Lamin A/C (zeige LMNA Antikörper) and caspase-6 could be valuable tools in the knowledge of oocyte in vitro destiny

Human Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Interaktionspartner

  1. These data suggest that caspase-6 deactivating mutations may contribute to multifactorial carcinogenic transformations.

  2. Caspase-6 undergoes helix-strand transition upon substrate binding. Caspase-6 shows distinctive conformational dynamics in its 130's region Local pKa Values of Key Amino Acid Residues within the 130's Region Vary between the Unliganded (Helical) and the VEID-bound (Strand) States of Caspase-6 .

  3. Following specific binding to and internalization into HER2 (zeige ERBB2 Antikörper)-overexpressing tumor cells, the e23sFv-Fdt-casp6 protein induced tumor cell apoptosis and inhibited the proliferation of HER2 (zeige ERBB2 Antikörper)-overexpressing A172 and U251MG cells in vitro, but not in U87MG cells with undetectable HER2 (zeige ERBB2 Antikörper)

  4. Results identified novel members of the CASP6 interactome and demonstrate that a number of them are involved in key signaling pathways observed in neurodegenerative diseases.

  5. The ability of sox11 (zeige SOX11 Antikörper) to reduce effector caspase (zeige CASP3 Antikörper) activity was also reflected in its capacity to reduce cell death following toxic insult. Interestingly, other sox (zeige PIPOX Antikörper) proteins also had the ability to reduce caspase-6 activity but to a lesser extent than sox11 (zeige SOX11 Antikörper)

  6. Caspase-6 plays a role in activating caspase-3 (zeige CASP3 Antikörper) in Tau truncation.

  7. unmodified STAT1 (zeige STAT1 Antikörper) is cleaved at multiple sites by caspase-3 (zeige CASP3 Antikörper) and caspase-6 in malignant undifferentiated hematopoietic cells

  8. p53 (zeige TP53 Antikörper) activity is an important upstream regulator of caspase-6 activity in Huntington's disease.

  9. In this study, the crystal structure of a full-length CASP6 zymogen mutant, proCASP6H121A, was solved.

  10. Caspase-6 is likely important in most tissues during early development but is less involved in adult tissues

Caspase 6 (CASP6) Antigen-Profil

Beschreibung des Gens

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Alternative names and synonyms associated with Caspase 6 (CASP6)

  • caspase 6, apoptosis-related cysteine peptidase (casp6) Antikörper
  • caspase 6 (CASP6) Antikörper
  • caspase-6 (CpipJ_CPIJ017008) Antikörper
  • Caspase-6 (casp6) Antikörper
  • caspase 6 (Casp6) Antikörper
  • caspase 6 (LOC100341546) Antikörper
  • caspase 6, apoptosis-related cysteine peptidase (CASP6) Antikörper
  • caspase 6, apoptosis-related cysteine peptidase (Casp6) Antikörper
  • caspase-6-like (LOC100517293) Antikörper
  • casp6 Antikörper
  • caspase-6 Antikörper
  • mCASP-6 Antikörper
  • MCH2 Antikörper
  • xCaspase-6 Antikörper
  • zgc:112960 Antikörper

Bezeichner auf Proteinebene für CASP6

caspase-6 , caspase 6, apoptosis-related cysteine protease , caspase-6a , caspase 6 , Caspase-6 , CASP-6 , apoptotic protease Mch-2 , apoptotic protease MCH-2

397818 Xenopus laevis
496478 Xenopus (Silurana) tropicalis
552927 Danio rerio
768261 Felis catus
6050542 Culex quinquefasciatus
100305305 Oncorhynchus mykiss
12368 Mus musculus
83584 Rattus norvegicus
100341546 Oryctolagus cuniculus
839 Homo sapiens
538409 Bos taurus
487899 Canis lupus familiaris
395477 Gallus gallus
100713360 Cavia porcellus
101119820 Ovis aries
100517293 Sus scrofa
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