anti-Caspase 3 (CASP3) Antikörper

anti-Caspase 3, Apoptosis-Related Cysteine Peptidase Antikörper (CASP3)
Auf finden Sie aktuell 645 Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Antikörper von 43 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Caspase 3 Kits (98) und Caspase 3 Proteine (47) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 845 Caspase 3 Produkte verfügbar.
A830040C14Rik, AC-3, Apopain, Cas3, Casp 3, Casp3, caspase-3, caspase 3, CC3, CG7788, CG14902, CPP32, CPP32B, crice, Decay, Dmel\\CG7788, Dmel\\CG14902, drice, Drosophila executioner caspase related to Apopain/Yama, ice, Lice, mldy, SCA-1, xcpp32, Yama

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Am meisten referenzierte anti-Caspase 3 Antikörper

  1. Human Polyclonal Caspase 3 Primary Antibody für IHC, WB - ABIN222873 : Fernando, Kelly, Balazsi, Slack, Megeney: Caspase 3 activity is required for skeletal muscle differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Zeige alle 24 Referenzen für 222873

  2. Human Polyclonal Caspase 3 Primary Antibody für WB - ABIN222951 : Atkin, Farg, Turner, Tomas, Lysaght, Nunan, Rembach, Nagley, Beart, Cheema, Horne: Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. in The Journal of biological chemistry 2006 (PubMed)
    Zeige alle 8 Referenzen für 222951

  3. Human Polyclonal Caspase 3 Primary Antibody für FACS, IHC (p) - ABIN655271 : Würstle, Laussmann, Rehm: The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 655271

  4. Human Polyclonal Caspase 3 Primary Antibody für EIA, IHC (p) - ABIN359724 : Wright, Farquhar, Aletrari, Ladds, Hodgkin: Identification of caspase 3 motifs and critical aspartate residues in human phospholipase D1b and phospholipase D2a. in Biochemical and biophysical research communications 2008 (PubMed)
    Zeige alle 3 Referenzen für 359724

  5. Human Polyclonal Caspase 3 Primary Antibody für DB, IHC (p) - ABIN650861 : Mei, Yong, Liu, Shi, Meinkoth, Dreyfuss, Yang: tRNA binds to cytochrome c and inhibits caspase activation. in Molecular cell 2010 (PubMed)
    Zeige alle 2 Referenzen für 650861

  6. Cow (Bovine) Polyclonal Caspase 3 Primary Antibody für IHC, WB - ABIN2774596 : Selvakumar, Smith-Windsor, Bonham, Sharma: N-myristoyltransferase 2 expression in human colon cancer: cross-talk between the calpain and caspase system. in FEBS letters 2006 (PubMed)
    Zeige alle 2 Referenzen für 2774596

  7. Human Polyclonal Caspase 3 Primary Antibody für WB - ABIN783310 : Gervais, Xu, Robertson, Vaillancourt, Zhu, Huang, LeBlanc, Smith, Rigby, Shearman, Clarke, Zheng, Van Der Ploeg, Ruffolo, Thornberry, Xanthoudakis, Zamboni, Roy, Nicholson: Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. in Cell 1999 (PubMed)
    Zeige alle 2 Referenzen für 783310

  8. Human Polyclonal Caspase 3 Primary Antibody für ELISA, WB - ABIN1536103 : Tewari, Quan, ORourke, Desnoyers, Zeng, Beidler, Poirier, Salvesen, Dixit: Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. in Cell 1995 (PubMed)

  9. Human Monoclonal Caspase 3 Primary Antibody für IHC (p), WB - ABIN400729 : Cartault, Munier, Benko, Desguerre, Hanein, Boddaert, Bandiera, Vellayoudom, Krejbich-Trotot, Bintner, Hoarau, Girard, Génin, de Lonlay, Fourmaintraux, Naville, Rodriguez, Feingold, Renouil, Munnich, Westhof, Fähling, Lyonnet, Henrion-Caude: Mutation in a primate-conserved retrotransposon reveals a noncoding RNA as a mediator of infantile encephalopathy. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

Weitere Antikörper gegen Caspase 3 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila.

  2. drICE plays an important role in activating corpse clearance in dying cells, and that an additional function of effector caspases is required for the activation of corpse clearance as well as that for carrying out cell death.

  3. Both autophagy and caspase activity are induced by 20-hydroxyecdysone during the larval-prepupal transition.

  4. The cleaved DIAP1 (zeige DIAPH1 Antikörper) binds drICE, inhibits its protease activity, and also targets drICE for ubiquitylation.

  5. Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1 (zeige ACE Antikörper), and ice

  6. Data suggest that the cleaved-Caspase-3 antibody recognizes multiple proteins including DCP-1 (zeige ACE Antikörper) and likely DRICE, but also at least one additional unknown protein, all of which require DRONC for epitope exposure.

  7. The caspase effector DRICE is activated during apoptosis in both mid- and late oogenesis; however, active DRICE was found more ubiquitously and at a higher level during germline cell death in midoogenesis.

  8. examination of inhibition by DIAP1 (zeige DIAPH1 Antikörper)

  9. Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells.

  10. A double-mutant analysis between drICE and death caspase-1 (dcp-1), another effector caspase, reveals that some cells (type I) strictly require drICE for apoptosis, whereas other cells (type II) require either drICE or dcp-1 (zeige ACE Antikörper).

Mouse (Murine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. SERT (zeige SLC6A4 Antikörper) protects trophoblast cells against apoptotic cell death in caspase-3 independent pathway by terminating the 5-HT (zeige DDC Antikörper) signaling.

  2. Prolonged treatment of human PMNs or mice bone marrow derived neutrophils (BMDN) with nitric oxide led to enhanced reactive oxygen species generation, caspase-8 (zeige CASP8 Antikörper)/caspase-3 cleavage, reduced mitochondrial membrane potential and finally cellular apoptosis.

  3. Induction of apoptosis in epithelial cancer cells was accompanied by a switch from glycolysis to oxidative phosphorylation, cytosol acidification and caspase-3 activation.

  4. ULK1 (zeige ULK1 Antikörper) is a novel substrate of Caspase-3 and upregulation of ULK1 (zeige ULK1 Antikörper) drives autophagy initiation in leukemia cells.

  5. These results indicate that the caspase-3/p120 RasGAP stress-sensing module impacts on carcinogen-induced liver cancer incidence but not sufficiently so as to affect overall survival.

  6. report that mutating the caspase-3 consensus site in the EAAT2 (zeige SLC1A2 Antikörper) sequence with an aspartate to asparagine mutation

  7. These studies suggest a link between Bik (zeige BIK Antikörper)-mediated caspase activation and cleavage of viral proteins.

  8. melatonin could inhibit TLR4 (zeige TLR4 Antikörper) expression in hypoxic microglia followed by suppression of caspase3 activation leading to decrease in production of proinflammatory mediators

  9. A significant emergence of GFP-expressing PCs and interneurons in symptomatic, but not non-symptomatic, SCA1 (zeige ATXN1 Antikörper) mice 2 weeks after the MSC (zeige MSC Antikörper) injection.

  10. Conversely, treatment with LY294002 (a selective inhibitor of Akt1 (zeige AKT1 Antikörper)) reversed the effects of quercetin. In conclusion, these findings highlight the important role of quercetin in protecting against cognitive deficits and inhibiting neuronal apoptosis via the Akt (zeige AKT1 Antikörper) signaling pathway. We believe that quercetin might prove to be a useful therapeutic component in treating cerebral I/R diseases in the near future.

Human Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. Prolonged treatment of human PMNs or mice bone marrow derived neutrophils (BMDN) with nitric oxide led to enhanced reactive oxygen species generation, caspase-8 (zeige CASP8 Antikörper)/caspase-3 cleavage, reduced mitochondrial membrane potential and finally cellular apoptosis.

  2. cleaved caspase-3 and caspase-3/8/9 could be biomarkers for tumorigenesis in oral tongue squamous cell carcinoma patients.

  3. TT genotype of CASP3 rs4643701 polymorphisms showed risk in CAD (zeige CAD Antikörper). CASP3 rs4647601 creates a new exon splicing enhancer.

  4. These findings shed some light on how a tumor cell may avert apoptosis using Hsp60 (zeige HSPD1 Antikörper) and point to the anti-cancer potential of drugs, such as CubipyOXA, which interfere with Hsp60 (zeige HSPD1 Antikörper)/pC3 (zeige PCSK1 Antikörper) complex formation, and thus allow the apoptotic cascade to proceed.

  5. Here the authors show that in macrophages SipA induces increased caspase-3 activation early in infection.

  6. SASH1 (zeige SASH1 Antikörper) is cleaved by caspase-3 following Ultraviolet C-induced apoptosis.

  7. Caspase 3 activation in dying glioma cells unfavorably supported post-irradiation angiogenesis.

  8. Bcl-xL (zeige BCL2L1 Antikörper) is an exosomal caspase-3 substrate and that this processing is required for the uptake of exosomes by recipient cells.

  9. CASP3 is a direct target of specific Epstein-Barr virus BART (zeige BSND Antikörper) miRNAs.

  10. Data suggest that EV71 infection in enterocytes does not inhibit phosphorylation of STAT1 (zeige STAT1 Antikörper)/2 induced by IFN-beta (zeige IFNB1 Antikörper), but p-STAT1 (zeige STAT1 Antikörper)/2 transport into the nucleus is significantly blocked; EV71 infection in enterocytes down-regulates expression of KPNA1 (zeige KPNA1 Antikörper) and induces degradation of cellular KPNA1 (zeige KPNA1 Antikörper) via caspase-3. [EV17 = Enterovirus 71]

Cow (Bovine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. Over-expression of STC-1 (zeige STC1 Antikörper) up-regulated Bcl-2 (zeige BCL2 Antikörper) protein expression and slightly down-regulated caspase-3 production in the damaged cells. Findings from this study suggest that STC-1 (zeige STC1 Antikörper) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. Data suggest that Escherichia coli infections (here, administration of LPS (zeige IRF6 Antikörper)) provokes luteolysis in diestrus, non-lactating cows and up-regulation of expression of caspase 3 in corpus luteum but has no effect on luteinization in the following cycle.

  3. Data suggest that activation of caspase-3 is likely involved in both spontaneous and induced apoptosis in bovine pre-implantation embryos.

  4. mRNA expression of Bax (zeige BAX Antikörper), Bcl-2 (zeige BCL2 Antikörper), caspase-3 and-7 cannot be used as a reliable apoptosis detection method.

  5. the capacity for blastocysts to undergo further development is related to degree of group II caspase activity

  6. Treatment of mammary epithelial cells with serotonin 1B and serotonin 2A receptor antagonists increased caspase-3 activity.

Pig (Porcine) Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. This study demonstrated that LAMPs from M. hyopneumoniae can induce apoptosis in St. Jude porcine lung epithelial cell line through the activation of caspase 3, caspase 8 (zeige CASP8 Antikörper), cyt c (zeige CYCS Antikörper), Bax (zeige BAX Antikörper), and p38 MAPK (zeige MAPK14 Antikörper).

  2. Caspase-3 (CC3) was shown to be more abundant in early-cleaving and more developmentally competent embryos compared to late-cleaving and less developmentally competent embryos.

  3. Results suggest that zearalenone induces apoptosis and necrosis of porcine granulosa cells in a dose-dependent manner via a caspase-3- and caspase-9 (zeige CASP9 Antikörper)-dependent mitochondrial pathway.

  4. FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (zeige MMP9 Antikörper) and MMP-2 (zeige MMP2 Antikörper), caspase-3 and BDNF (zeige BDNF Antikörper)

  5. both caspase-3-dependent and -independent pathways of programmed cell death increased upon Salmonella typhimurium infection.

  6. clonidine administration prior to hypoxia prevents the hypoxia-induced increase in the activity of caspase-3 in the cerebral cortex.

  7. Suppressive effect of FSH (zeige BRD2 Antikörper) and LH on p53 (zeige TP53 Antikörper) expression and caspase-3 activity with parallel increase in bcl-2 (zeige BCL2 Antikörper) expression and increased P production was observed

  8. Ischemic preconditioning exerts a powerful protective effect against hepatic ischemia-reperfusion injury in the early phase of reperfusion, which may be mediated by preservation of mitochondrial structure and inhibition of caspase-3 activity.

Rabbit Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 expression as well as low Bcl-2 (zeige BCL2 Antikörper) expression.

  2. This study revealed that the 810-nm low-level laser can improve cartilage structure, prevent articular cartilage degradation and significantly decrease the expression of caspase-3 in this surgery-induced osteoarthritis model.

  3. Morphine hypoxic preconditioning can protect rabbits against acute kidney hypoxic/reoxygenation injury by decreasing expression of caspase-3.

  4. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 (zeige BCL2 Antikörper) and down-regulating the activation of caspase-3.

  5. High frequency oscillatory ventilation combined with exogenous pulmonary surfactant can decrease the concentration of caspase-3 and p73 (zeige ARHGAP24 Antikörper) rabbit with acute respiratory failure.

Xenopus laevis Caspase 3, Apoptosis-Related Cysteine Peptidase (CASP3) Interaktionspartner

  1. Hyperosmotic Shock Engages Two Positive Feedback Loops through Caspase-3-dependent Proteolysis of JNK1 (zeige MAPK8 Antikörper)-2 and Bid (zeige BID Antikörper).

  2. in the developing diencephalon, Caspase3 acts downstream of Barhl2 (zeige BARHL2 Antikörper) in limiting neuroepithelial cell proliferation by inhibiting beta-catenin (zeige CTNNB1 Antikörper) activation.

  3. PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53 (zeige TP53 Antikörper)-dependent and p53 (zeige TP53 Antikörper)-independent apoptosis during development.

Caspase 3 (CASP3) Antigen-Profil

Beschreibung des Gens

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Alternative names and synonyms associated with Caspase 3 (CASP3)

  • caspase 3, apoptosis-related cysteine peptidase (CASP3) Antikörper
  • death executioner caspase related to Apopain/Yama (decay) Antikörper
  • CG7788 gene product from transcript CG7788-RA (Ice) Antikörper
  • caspase 3 (Casp3) Antikörper
  • caspase 3, apoptosis-related cysteine peptidase (Casp3) Antikörper
  • caspase 3, apoptosis-related cysteine peptidase (casp3) Antikörper
  • A830040C14Rik Antikörper
  • AC-3 Antikörper
  • Apopain Antikörper
  • Cas3 Antikörper
  • Casp 3 Antikörper
  • Casp3 Antikörper
  • caspase-3 Antikörper
  • caspase 3 Antikörper
  • CC3 Antikörper
  • CG7788 Antikörper
  • CG14902 Antikörper
  • CPP32 Antikörper
  • CPP32B Antikörper
  • crice Antikörper
  • Decay Antikörper
  • Dmel\\CG7788 Antikörper
  • Dmel\\CG14902 Antikörper
  • drice Antikörper
  • Drosophila executioner caspase related to Apopain/Yama Antikörper
  • ice Antikörper
  • Lice Antikörper
  • mldy Antikörper
  • SCA-1 Antikörper
  • xcpp32 Antikörper
  • Yama Antikörper

Bezeichner auf Proteinebene für CASP3

Caspase-3-like protein , caspase-3 , CG14902-PA , Caspase-3 , caspase 3 , caspase-3 protein , cleaved caspase 3 , decay-PA , CG7788-PA , Ice-PA , drice , interleukin-1beta-converting enzyme , CASP-3 , CPP-32 , SCA-1 , SREBP cleavage activity 1 , caspase 3, apoptosis related cysteine protease , cysteine protease CPP32 , protein Yama , CPP32beta , Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease) , Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease) , IRP , apopain , yama protein , PARP cleavage protease , caspase 3, apoptosis-related cysteine protease , procaspase3

100034083 Equus caballus
42008 Drosophila melanogaster
43514 Drosophila melanogaster
12367 Mus musculus
25402 Rattus norvegicus
836 Homo sapiens
408016 Bos taurus
403567 Canis lupus familiaris
397244 Sus scrofa
443031 Ovis aries
100008840 Oryctolagus cuniculus
395476 Gallus gallus
100718309 Cavia porcellus
493932 Felis catus
397720 Xenopus laevis
461669 Pan troglodytes
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