PTK7 Antikörper

Produktnummer ABIN969374

Produktdetails anti-PTK7 Antikörper

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PTK7 expressed in E. coli.

Klon: 4F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-PTK7 Antikörper (ABIN969374)

Shin, Maeng, Jung, Min, Kwon, Lee: "Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis." in: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 793-8, (2008) (PubMed).

Details zu PTK7

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Andere Bezeichnung: PTK7 (PTK7 Produkte)

Synonyme: PTK7 antikoerper, CCK-4 antikoerper, CCK4 antikoerper, Srf antikoerper, 8430404F20Rik antikoerper, chz antikoerper, mPTK7/CCK4 antikoerper, KLG antikoerper, protein tyrosine kinase 7 (inactive) antikoerper, protein tyrosine kinase 7 antikoerper, PTK7 protein tyrosine kinase 7 antikoerper, PTK7 antikoerper, Ptk7 antikoerper

Hintergrund:

Description: Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

Aliases: CCK4, PTK7

Molekulargewicht: 118 kDa

Gen-ID: 5754

HGNC: 5754

Pathways: RTK Signalweg, Tube Formation