MYL2 Antikörper
Kurzübersicht für MYL2 Antikörper (ABIN969302)
Target
Alle MYL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- MYL2 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of MYL2 expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 14, Issue 5, pp. 339-50, (2004) (PubMed).
: "Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells." in: Oncogene, Vol. 21, Issue 38, pp. 5852-60, (2002) (PubMed).
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- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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Andere Bezeichnung
- MYL2
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Hintergrund
- MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
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Molekulargewicht
- 19 kDa
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Gen-ID
- 4633
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UniProt
- P10916
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Pathways
- Myometrial Relaxation and Contraction
Target
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