MYL2 Antikörper

Produktnummer ABIN969302

Produktdetails anti-MYL2 Antikörper

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MYL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of MYL2 expressed in E. coli.

Klon: 7C9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-MYL2 Antikörper (ABIN969302)

Sachdev, Raychowdhury, Sarkar: "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 14, Issue 5, pp. 339-50, (2004) (PubMed).

Ueda, Murata-Hori, Tatsuka, Hosoya: "Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells." in: Oncogene, Vol. 21, Issue 38, pp. 5852-60, (2002) (PubMed).

Details zu MYL2

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Andere Bezeichnung: MYL2 (MYL2 Produkte)

Synonyme: CMH10 antikoerper, MLC2 antikoerper, 2410014J02Rik antikoerper, MLC-2 antikoerper, Mlc2 antikoerper, MLC-2v antikoerper, Mlc2v antikoerper, Mylpc antikoerper, Mlc-2 antikoerper, myl2 antikoerper, zgc:136848 antikoerper, XMLC2 antikoerper, cmh10 antikoerper, mlc2 antikoerper, G2 antikoerper, MLC-2A antikoerper, MLC2V antikoerper, myosin light chain 2 antikoerper, myosin light chain, phosphorylatable, fast skeletal muscle antikoerper, myosin, light polypeptide 2, regulatory, cardiac, slow antikoerper, myosin, light chain 2b, regulatory, cardiac, slow antikoerper, myosin light chain 2 S homeolog antikoerper, myosin, light chain 2, regulatory, cardiac, slow antikoerper, MYL2 antikoerper, Mylpf antikoerper, Myl2 antikoerper, myl2b antikoerper, myl2.S antikoerper

Hintergrund:

Description: MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Aliases: MLC2, CMH10, DKFZp779C0562

Molekulargewicht: 19 kDa

Gen-ID: 4633

HGNC: 4633

Pathways: Myometrial Relaxation and Contraction