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UBE2I Antikörper (AA 26-156)

UBE2I Reaktivität: Human, Maus, Ratte, Huhn, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 50-Ubc9 unconjugated
Produktnummer ABIN968154
  • Target Alle UBE2I Antikörper anzeigen
    UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
    Bindungsspezifität
    • 12
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 26-156
    Reaktivität
    • 76
    • 34
    • 33
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn, Hund
    Wirt
    • 63
    • 12
    • 2
    Maus
    Klonalität
    • 53
    • 24
    Monoklonal
    Konjugat
    • 37
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser UBE2I Antikörper ist unkonjugiert
    Applikation
    • 53
    • 31
    • 27
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Hund, Ratte (Rattus), Maus, Huhn
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human Ubc9 aa. 26-156
    Klon
    50-Ubc9
    Isotyp
    IgG2a
    Top Product
    Discover our top product UBE2I Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

    Buschmann, Lerner, Lee, Ronai: "The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40389-95, (2001) (PubMed).

    Kovalenko, Plug, Haaf, Gonda, Ashley, Ward, Radding, Golub: "Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 7, pp. 2958-63, (1996) (PubMed).

  • Target
    UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
    Andere Bezeichnung
    Ubc9 (UBE2I Produkte)
    Synonyme
    C358B7.1 antikoerper, P18 antikoerper, UBC9 antikoerper, ubc9 antikoerper, ube2ia antikoerper, zUbc9 antikoerper, 5830467E05Rik antikoerper, F830028O17Rik antikoerper, Ubce2i antikoerper, Ubce9 antikoerper, UbcE2A antikoerper, ubce9 antikoerper, T13J8.70 antikoerper, T13J8_70 antikoerper, UBIQUITIN-PROTEIN LIGASE antikoerper, ubiquitin conjugating enzyme 9 antikoerper, ubiquitin conjugating enzyme E2 I antikoerper, ubiquitin-conjugating enzyme E2Ib antikoerper, ubiquitin-conjugating enzyme E2L antikoerper, ubiquitin-conjugating enzyme E2I antikoerper, ubiquitin conjugating enzyme E2I S homeolog antikoerper, ubiquitin conjugating enzyme 9 antikoerper, SUMO-conjugating enzyme UBC9 antikoerper, UBE2I antikoerper, ube2ib antikoerper, UBE2L antikoerper, Ube2i antikoerper, ube2i.S antikoerper, UBC9 antikoerper, ubc-9 antikoerper, LOC108703134 antikoerper
    Hintergrund
    Progression of the mammalian cell cycle is primarily regulated by phosphorylation/dephosphorylation and synthesis/degradation of many key proteins. Ubiquitin, a soluble protein of 76 amino acids, is enzymatically attached to an e-NH2-Lys in a target protein. Ubiquitination is a hallmark for rapid protein degradation of the target protein in the proteosome (a cytoplasmic complex of proteases). Human homologs of the yeast ubiquitin-conjugating enzymes (Ubc) have been reported, including Ubc9. Ubc9 is 158 amino acids with an apparent molecular weight of 18kDa. Although ubiquitously expressed, the highest levels of Ubc9 are found in testis and thymus. Ubc9 was localized to the synaptonemal complex in male mouse sex chromosomes. Furthermore, Ubc9 interacts with the recombination protein Rad51, thus suggesting an important role for Ubc9 during meiosis.
    Molekulargewicht
    18 kDa
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
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