WIF1 Antikörper

Produktnummer ABIN967258

Dieser Maus Monoklonal Antikörper detektiert spezifisch WIF1 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für WIF1 Antikörper (ABIN967258)

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WIF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: 1G5

Produktdetails anti-WIF1 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human WIF1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-WIF1 Antikörper (ABIN967258)

Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." in: BMC cancer, Vol. 9, pp. 217, (2009) (PubMed).

Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." in: Cancer research, Vol. 69, Issue 22, pp. 8603-10, (2009) (PubMed).

Details zu WIF1

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Andere Bezeichnung: WIF1

Hintergrund: The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Synonyms: WIF-1, WIF

Molekulargewicht: 42kDa

Gen-ID: 11197

Pathways: WNT Signalweg, Positive Regulation of fat Cell Differentiation