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Keratin 7/17 Antikörper

KRT7/17 Reaktivität: Human, Rind (Kuh), Schwein WB, IP, ICC, IHC (p) Wirt: Maus Monoclonal C-46 unconjugated
Produktnummer ABIN94296
  • Target Alle Keratin 7/17 (KRT7/17) Antikörper anzeigen
    Keratin 7/17 (KRT7/17)
    Reaktivität
    Human, Rind (Kuh), Schwein
    Wirt
    • 4
    Maus
    Klonalität
    • 4
    Monoklonal
    Konjugat
    • 4
    Dieser Keratin 7/17 Antikörper ist unkonjugiert
    Applikation
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    The antibody C-46 reacts with cytokeratin peptides 7 and 17 (54 and 46 kDa). Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues.
    Keine Kreuzreaktivität
    Maus, Kaninchen, Ratte
    Kreuzreaktivität (Details)
    Porcine, Human, Bovine
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Cytoskeleton preparation of HeLa human cervix carcinoma cell line.
    Klon
    C-46
    Isotyp
    IgG1
  • Applikationshinweise
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, pretreatment: 0,1 % pepsin, 30 min, 37 °C, incubation 4 °C overnight, chromogen DAB, positive tissue: pancreas.
    Western blotting: Recommended dilution: 1-2 μg/mL, positive control: HeLa cells.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Vojt?sek, Stasková, Nenutil, Bártková, Kovarík, Rejthar, Bártek: "A panel of monoclonal antibodies to keratin no. 7: characterization and value in tumor diagnosis." in: Neoplasma, Vol. 37, Issue 3, pp. 333-42, (1990) (PubMed).

  • Target
    Keratin 7/17 (KRT7/17)
    Andere Bezeichnung
    Cytokeratin 7+17 (KRT7/17 Produkte)
    Synonyme
    KRT7 antikoerper, CK7 antikoerper, keratin 7 antikoerper, KRT7 antikoerper
    Hintergrund
    Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.,K7, K17, CK7, CD17, CK17, CYK7, CYK17, KRT7, KRT17, SCL, K2C7
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