COL1A1 Antikörper (C-Term)

Produktnummer ABIN929420

Der Kaninchen Polyklonal anti-COL1A1 Antikörper wird verwendet zum Nachweis von COL1A1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für COL1A1 Antikörper (C-Term) (ABIN929420)

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COL1A1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: COL1 A1 antibody was raised in rabbit using the C terminal of COL1 1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

COL1A1 Blocking Peptide, (ABIN938780), is also available for use as a blocking control in assays to test for specificity of this COL1A1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu COL1A1

Target: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Andere Bezeichnung: COL1A1

Hintergrund: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Synonyms: Polyclonal COL1A1 antibody, Anti-COL1A1 antibody, collagen, type I, alpha 1 antibody, OI4 antibody.

Pathways: Sensory Perception of Sound, Autophagie, Growth Factor Binding