PFKM Antikörper (C-Term)

Produktnummer ABIN926683

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PFKM in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PFKM Antikörper (C-Term) (ABIN926683)

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PFKM Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: PFKM antibody was raised in rabbit using the C terminal of PFKM as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

PFKM Blocking Peptide, (ABIN5615327), is also available for use as a blocking control in assays to test for specificity of this PFKM antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PFKM

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Andere Bezeichnung: PFKM

Hintergrund: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. Synonyms: Polyclonal PFKM antibody, Anti-PFKM antibody, phosphofructokinase, muscle antibody, GSD7 antibody, MGC8699 antibody, PFK-1 antibody, PFK1 antibody, PFKA antibody, PFKX antibody.

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effekt