TLR11 Antikörper (Internal Region)

Produktnummer ABIN920631

Der Kaninchen Polyklonal anti-TLR11 Antikörper (ABIN920631) detektiert spezifisch TLR11 in WB und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für TLR11 Antikörper (Internal Region) (ABIN920631)

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Produktdetails anti-TLR11 Antikörper

Bindungsspezifität: Internal Region

Produktmerkmale: Positive Control: RAW26.7 cell lysate. Located in membrane.

Aufreinigung: Antigen Immunoaffinity purified

Immunogen: Rabbit polyclonal TLR11 antibody was raised against a peptide corresponding to 16 amino acids near the middle of mouse TLR11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: use at 0.5-2 µg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.02% sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Hintergrund: Toll-like receptors (TRLs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TRL11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacterial, and mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. Synonyms:

Molekulargewicht: 106 kDa

Pathways: Activation of Innate immune Response