CACNA1A Antikörper (AA 1401-1500) (AbBy Fluor® 647)

Produktnummer ABIN886090

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CACNA1A in IF (cc) und IF (p). Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für CACNA1A Antikörper (AA 1401-1500) (AbBy Fluor® 647) (ABIN886090)

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1A Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CACNA1A Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 1401-1500

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACNA1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CACNA1A

Target: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Andere Bezeichnung: CACNA1A/Cav2.1

Hintergrund:

Synonyms: APCA, BI, Brain calcium channel 1, Brain calcium channel I, Cach4, Cacn3, Cacna1a, Cacnl1a4, Calcium channel alpha 1A subunit, Calcium channel L type alpha 1 polypeptide, Calcium channel L type alpha-1 polypeptide isoform 4, Calcium channel voltage dependent, P/Q type alpha 1A subunit, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, RAT brain class A, RBA-I, SCA6, Voltage-dependent P/Q-type calcium channel alpha-1A subunit, Voltage-gated calcium channel alpha subunit Cav2.1, CAC1A_HUMAN.

Background: Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

Gen-ID: 773

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process