Tamalin/GRASP Antikörper (AA 814-818)

Produktnummer ABIN871663

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Tamalin/GRASP in WB. Es zeigt Reaktivität gegenüber Proben von Maus, Ratte und Human.

Kurzübersicht für Tamalin/GRASP Antikörper (AA 814-818) (ABIN871663)

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Reaktivität: Maus, Ratte, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tamalin/GRASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Tamalin/GRASP Antikörper

Bindungsspezifität: AA 814-818

Spezifität: The antibody detects endogenous level of total GRASP protein.

Aufreinigung: Affinity purified

Immunogen: Peptide sequence around AA 814-818 (Q-E-I-V-R ) derived from Rat GRASP. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Tamalin/GRASP

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Andere Bezeichnung: GRASP

Hintergrund: GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid protein encoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipper region and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.

Molekulargewicht: 95 kDa

Gen-ID: 56850

NCBI Accession: NP_064522

UniProt: Q9JHZ4