Tamalin/GRASP Antikörper (C-Term)

Produktnummer ABIN372659

Produktdetails anti-Tamalin/GRASP Antikörper

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte, Human, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tamalin/GRASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody is specific for the ~95k GRASP protein.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Canine, Human and Mouse.
Species reactivity (tested):Rat.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu Tamalin/GRASP

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Andere Bezeichnung: GRASP (GRASP Produkte)

Synonyme: GRASP antikoerper, tamalin antikoerper, TAMALIN antikoerper, general receptor for phosphoinositides 1 associated scaffold protein antikoerper, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein antikoerper, GRASP antikoerper, grasp antikoerper, Grasp antikoerper

Hintergrund: PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).Synonyms: GRP1-associated scaffold protein, General receptor for phosphoinositides 1-associated scaffold protein

Gen-ID: 192254

NCBI Accession: NP_620249

UniProt: Q8R4T5