SOCS3 Antikörper

Produktnummer ABIN2732331

Der Maus Monoklonal anti-SOCS3 Antikörper wird verwendet zum Nachweis von SOCS3 in Proben von Human. Er wurde validiert für WB, IHC, IF und FACS.

Kurzübersicht für SOCS3 Antikörper (ABIN2732331)

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOCS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 5D4

Produktdetails anti-SOCS3 Antikörper

Produktmerkmale: Homo sapiens suppressor of cytokine signaling 3 (SOCS3)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SOCS3

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Andere Bezeichnung: SOCS3

Hintergrund: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Molekulargewicht: 24.6 kDa

Gen-ID: 9021

NCBI Accession: NM_003955

HGNC: 9021

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C