FXYD1 Antikörper (pSer88) (Cy5.5)

Produktnummer ABIN800768

Der Kaninchen Polyklonal anti-FXYD1 Antikörper wird verwendet zum Nachweis von FXYD1 in Proben von Human. Er wurde validiert für WB, IF (cc) und IF (p).

Kurzübersicht für FXYD1 Antikörper (pSer88) (Cy5.5) (ABIN800768)

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FXYD1 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-FXYD1 Antikörper (Cy5.5)

Bindungsspezifität: pSer88

Homologie: Human,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FXYD1 around the phosphorylation site of Ser88

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FXYD1

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Andere Bezeichnung: FXYD1

Hintergrund:

Synonyms: FXYD1 phospho S88, FXYD1 phospho Ser88, p-FXYD1 phospho S88, FXYD domain containing ion transport regulator 1, Phospholemman, PLM, fxyd1, PLM_HUMAN, FXYD domain-containing ion transport regulator 1.

Background: PLM (FXYD1)is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. PLM may be phosphorylated by several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity.

Gen-ID: 5348