POLG2 Antikörper (N-Term)
Kurzübersicht für POLG2 Antikörper (N-Term) (ABIN786524)
Target
Alle POLG2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- KSHAELEGNG EHPEAPGSGE GSEALLEICQ RRHFLSGSKQ QLSRDSLLSG
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against POLG2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 485 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
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Andere Bezeichnung
- POLG2
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Hintergrund
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This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Alias Symbols: HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB
Protein Interaction Partner: PARP1, SUMO1,
Protein Size: 485 -
Molekulargewicht
- 53 kDa
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Gen-ID
- 11232
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NCBI Accession
- NM_007215, NP_009146
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UniProt
- Q9UHN1
Target
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