S100A8 Antikörper (Middle Region)

Produktnummer ABIN786406

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch S100A8 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für S100A8 Antikörper (Middle Region) (ABIN786406)

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-S100A8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: QYIRKKGADV WFKELDINTD GAVNFQEFLI LVIKMGVAAH KKSHEESHKE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against S100A8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 93 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu S100A8

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Andere Bezeichnung: S100A8

Hintergrund: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
Alias Symbols: 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF, P8
Protein Interaction Partner: NCF2, TUBGCP3, SUMO2, S100A8, BECN1, BAG3, SRP1, SEC27, CDC34, CDC53, TRAF3IP1, PAXIP1, ESR1, APP, SHC1, COPS5, TFAP4, CDK2, SIRT7, UBC, CDKN1A, POT1, TERF2, TERF1, S100A9, SLX1B, DMWD, PDCD11, LRIF1, CEACAM3, KLC2, RAB17, IGSF21, CHGB, C14orf1, UNC119, P
Protein Size: 93

Molekulargewicht: 10 kDa

Gen-ID: 6279

NCBI Accession: NM_002964, NP_002955

UniProt: P05109

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine