XRCC3 Antikörper (Middle Region)

Produktnummer ABIN786381

Der Kaninchen Polyklonal anti-XRCC3 Antikörper (ABIN786381) detektiert spezifisch XRCC3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Hund, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für XRCC3 Antikörper (Middle Region) (ABIN786381)

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Reaktivität: Human, Maus, Hund, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-XRCC3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LAVQFPRQHG GLEAGAVYIC TEDAFPHKRL QQLMAQQPRL RTDVPGELLQ

Homologie: Cow: 83%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against XRCC3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 346 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu XRCC3

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Andere Bezeichnung: XRCC3

Hintergrund: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alias Symbols: CMM6
Protein Interaction Partner: SWSAP1, ZSWIM7, UBC, FANCG, BRCA2, ZNHIT3, RAD51D, RAD51C, RAD51,
Protein Size: 346

Molekulargewicht: 38 kDa

Gen-ID: 7517

NCBI Accession: NM_005432, NP_005423

UniProt: O43542

Pathways: DNA Reparatur